Si-Eun. Yoo, et.al., Gpx4 ablation in adult mice results in a lethal phenotype accompanied by neuronal loss in brain., Free radical biology & medicine, 2012, 52

http://rdf.ncbi.nlm.nih.gov/pubmed/22401858

Si-Eun. Yoo, et.al., Gpx4 ablation in adult mice results in a lethal phenotype accompanied by neuronal loss in brain., Free radical biology & medicine, 2012, 52

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gpx4<tm1.1Qra>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5425616

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• cachexia_Gpx4<tm1.1Qra>/Gpx4<tm1.1Qra>,Gt(ROSA)26Sor<tm1(cre/ERT)Nat>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0005150I129S1Sv129S6SvEvTac129X1SvJC57BL6SJLGpx4tm11QraGpx4tm11QraGtROSA26Sortm1creERTNatGtROSA26SorGtROSA26SorGtROSA26Sortm1creERTNatGpx4tm11Qra
• lethality, complete penetrance_Gpx4<tm1.1Qra>/Gpx4<tm1.1Qra>,Gt(ROSA)26Sor<tm1(cre/ERT)Nat>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0011400I129S1Sv129S6SvEvTac129X1SvJC57BL6SJLGpx4tm11QraGpx4tm11QraGtROSA26Sortm1creERTNatGtROSA26SorGtROSA26SorGtROSA26Sortm1creERTNatGpx4tm11Qra
• neurodegeneration_Gpx4<tm1.1Qra>/Gpx4<tm1.1Qra>,Gt(ROSA)26Sor<tm1(cre/ERT)Nat>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0002229I129S1Sv129S6SvEvTac129X1SvJC57BL6SJLGpx4tm11QraGpx4tm11QraGtROSA26Sortm1creERTNatGtROSA26SorGtROSA26SorGtROSA26Sortm1creERTNatGpx4tm11Qra
• lethargy_Gpx4<tm1.1Qra>/Gpx4<tm1.1Qra>,Gt(ROSA)26Sor<tm1(cre/ERT)Nat>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0005202I129S1Sv129S6SvEvTac129X1SvJC57BL6SJLGpx4tm11QraGpx4tm11QraGtROSA26Sortm1creERTNatGtROSA26SorGtROSA26SorGtROSA26Sortm1creERTNatGpx4tm11Qra
• abnormal cellular respiration_Gpx4<tm1.1Qra>/Gpx4<tm1.1Qra>,Gt(ROSA)26Sor<tm1(cre/ERT)Nat>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0010954I129S1Sv129S6SvEvTac129X1SvJC57BL6SJLGpx4tm11QraGpx4tm11QraGtROSA26Sortm1creERTNatGtROSA26SorGtROSA26SorGtROSA26Sortm1creERTNatGpx4tm11Qra
• astrocytosis_Gpx4<tm1.1Qra>/Gpx4<tm1.1Qra>,Gt(ROSA)26Sor<tm1(cre/ERT)Nat>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0003354I129S1Sv129S6SvEvTac129X1SvJC57BL6SJLGpx4tm11QraGpx4tm11QraGtROSA26Sortm1creERTNatGtROSA26SorGtROSA26SorGtROSA26Sortm1creERTNatGpx4tm11Qra
• increased hepatocyte apoptosis_Gpx4<tm1.1Qra>/Gpx4<tm1.1Qra>,Gt(ROSA)26Sor<tm1(cre/ERT)Nat>/Gt(ROSA)26Sor<+>
  http://metadb.riken.jp/0003887I129S1Sv129S6SvEvTac129X1SvJC57BL6SJLGpx4tm11QraGpx4tm11QraGtROSA26Sortm1creERTNatGtROSA26SorGtROSA26SorGtROSA26Sortm1creERTNatGpx4tm11Qra

class

http://purl.org/net/cito/citesAsAuthority

• Gpx4<tm1.1Qra>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5425616