Whitney E. Purtha, et.al., Spontaneous mutation of the Dock2 gene in Irf5-/- mice complicates interpretation of type I interferon production and antibody responses., Proceedings of the National Academy of Sciences of the United States of America, 2012, 109

http://rdf.ncbi.nlm.nih.gov/pubmed/22431588

Whitney E. Purtha, et.al., Spontaneous mutation of the Dock2 gene in Irf5-/- mice complicates interpretation of type I interferon production and antibody responses., Proceedings of the National Academy of Sciences of the United States of America, 2012, 109

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Dock2<m1Hsd>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5319388

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased follicular B cell number_Dock2<m1Hsd>/Dock2<m1Hsd>,Irf5<tm1Ttg>/Irf5<tm1Ttg>
  http://metadb.riken.jp/0008174B6NHsdCgIrf5tm1TtgDock2m1HsdDock2m1HsdDock2m1HsdIrf5tm1TtgIrf5tm1TtgIrf5tm1TtgDock2m1Hsd
• abnormal response to infection_Dock2<m1Hsd>/Dock2<m1Hsd>,Irf5<tm1Ttg>/Irf5<tm1Ttg>
  http://metadb.riken.jp/0005025B6NHsdCgIrf5tm1TtgDock2m1HsdDock2m1HsdDock2m1HsdIrf5tm1TtgIrf5tm1TtgIrf5tm1TtgDock2m1Hsd
• abnormal B cell differentiation_Dock2<m1Hsd>/Dock2<m1Hsd>,Irf5<tm1Ttg>/Irf5<tm1Ttg>
  http://metadb.riken.jp/0002144B6NHsdCgIrf5tm1TtgDock2m1HsdDock2m1HsdDock2m1HsdIrf5tm1TtgIrf5tm1TtgIrf5tm1TtgDock2m1Hsd
• decreased interferon-alpha secretion_Irf5<tm1Ttg>/Irf5<tm1Ttg>
  http://metadb.riken.jp/0008563B6129P2Irf5tm1TtgIrf5tm1TtgIrf5tm1TtgIrf5tm1Ttg
• decreased plasmacytoid dendritic cell number_Dock2<m1Hsd>/Dock2<m1Hsd>,Irf5<tm1Ttg>/Irf5<tm1Ttg>
  http://metadb.riken.jp/0008124B6NHsdCgIrf5tm1TtgDock2m1HsdDock2m1HsdDock2m1HsdIrf5tm1TtgIrf5tm1TtgIrf5tm1TtgDock2m1Hsd
• increased plasmacytoid dendritic cell number_Dock2<m1Hsd>/Dock2<m1Hsd>,Irf5<tm1Ttg>/Irf5<tm1Ttg>
  http://metadb.riken.jp/0008524B6NHsdCgIrf5tm1TtgDock2m1HsdDock2m1HsdDock2m1HsdIrf5tm1TtgIrf5tm1TtgIrf5tm1TtgDock2m1Hsd
• decreased interferon-alpha secretion_Dock2<m1Hsd>/Dock2<m1Hsd>,Irf5<tm1Ttg>/Irf5<tm1Ttg>
  http://metadb.riken.jp/0008563B6NHsdCgIrf5tm1TtgDock2m1HsdDock2m1HsdDock2m1HsdIrf5tm1TtgIrf5tm1TtgIrf5tm1TtgDock2m1Hsd
• decreased interleukin-6 secretion_Irf5<tm1Ttg>/Irf5<tm1Ttg>
  http://metadb.riken.jp/0008706B6129P2Irf5tm1TtgIrf5tm1TtgIrf5tm1TtgIrf5tm1Ttg
• absent marginal zone B cells_Dock2<m1Hsd>/Dock2<m1Hsd>,Irf5<tm1Ttg>/Irf5<tm1Ttg>
  http://metadb.riken.jp/0008183B6NHsdCgIrf5tm1TtgDock2m1HsdDock2m1HsdDock2m1HsdIrf5tm1TtgIrf5tm1TtgIrf5tm1TtgDock2m1Hsd
• increased immature B cell number_Dock2<m1Hsd>/Dock2<m1Hsd>,Irf5<tm1Ttg>/Irf5<tm1Ttg>
  http://metadb.riken.jp/0008214B6NHsdCgIrf5tm1TtgDock2m1HsdDock2m1HsdDock2m1HsdIrf5tm1TtgIrf5tm1TtgIrf5tm1TtgDock2m1Hsd
• decreased tumor necrosis factor secretion_Irf5<tm1Ttg>/Irf5<tm1Ttg>
  http://metadb.riken.jp/0008561B6129P2Irf5tm1TtgIrf5tm1TtgIrf5tm1TtgIrf5tm1Ttg
• decreased splenocyte number_Dock2<m1Hsd>/Dock2<m1Hsd>,Irf5<tm1Ttg>/Irf5<tm1Ttg>
  http://metadb.riken.jp/0009339B6NHsdCgIrf5tm1TtgDock2m1HsdDock2m1HsdDock2m1HsdIrf5tm1TtgIrf5tm1TtgIrf5tm1TtgDock2m1Hsd
• abnormal response to infection_Irf5<tm1Ttg>/Irf5<tm1Ttg>
  http://metadb.riken.jp/0005025B6129P2Irf5tm1TtgIrf5tm1TtgIrf5tm1TtgIrf5tm1Ttg
• increased B cell number_Dock2<m1Hsd>/Dock2<m1Hsd>,Irf5<tm1Ttg>/Irf5<tm1Ttg>
  http://metadb.riken.jp/0005014B6NHsdCgIrf5tm1TtgDock2m1HsdDock2m1HsdDock2m1HsdIrf5tm1TtgIrf5tm1TtgIrf5tm1TtgDock2m1Hsd

class

http://purl.org/net/cito/citesAsAuthority

• Dock2<m1Hsd>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5319388