Haoqiang. Ying, et.al., Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism., Cell, 2012, 149

http://rdf.ncbi.nlm.nih.gov/pubmed/22541435

Haoqiang. Ying, et.al., Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism., Cell, 2012, 149

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-Kras*G12D)#Rdp
  http://metadb.riken.jp/db/mgi_rdf/MGI:5648530

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased pancreatic ductal adenocarcinoma incidence_Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>/Gt(ROSA)26Sor<+>,Ptf1a<tm1.1(cre)Cvw>/Ptf1a<+>,Tg(tetO-Kras*G12D)#Rdp/0,Trp53<tm1Brn>/Trp53<+>
  http://metadb.riken.jp/0009151I129P2OlaHsd129S1Sv129X1SvJC57BL6FVBNGtROSA26Sortm1rtTAEGFPNagyGtROSA26SorPtf1atm11creCvwPtf1aTgtetOKrasG12DRdp0Trp53tm1BrnTrp53Ptf1atm11creCvwTrp53GtROSA26Sortm1rtTAEGFPNagyGtROSA26SorTgtetOKrasG12DRdpTrp53tm1BrnPtf1a
• increased pancreatic intraepithelial neoplasia incidence_Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>/Gt(ROSA)26Sor<+>,Ptf1a<tm1.1(cre)Cvw>/Ptf1a<+>,Tg(tetO-Kras*G12D)#Rdp/0
  http://metadb.riken.jp/0009152I129S1Sv129X1SvJC57BL6FVBNGtROSA26Sortm1rtTAEGFPNagyGtROSA26SorPtf1atm11creCvwPtf1aTgtetOKrasG12DRdp0GtROSA26SorPtf1aTgtetOKrasG12DRdpPtf1atm11creCvwGtROSA26Sortm1rtTAEGFPNagy
• pancreatic acinar-to-ductal metaplasia_Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>/Gt(ROSA)26Sor<+>,Ptf1a<tm1.1(cre)Cvw>/Ptf1a<+>,Tg(tetO-Kras*G12D)#Rdp/0
  http://metadb.riken.jp/0013221I129S1Sv129X1SvJC57BL6FVBNGtROSA26Sortm1rtTAEGFPNagyGtROSA26SorPtf1atm11creCvwPtf1aTgtetOKrasG12DRdp0GtROSA26SorPtf1aTgtetOKrasG12DRdpPtf1atm11creCvwGtROSA26Sortm1rtTAEGFPNagy
• increased pancreatic ductal adenocarcinoma incidence_Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>/Gt(ROSA)26Sor<+>,Ptf1a<tm1.1(cre)Cvw>/Ptf1a<+>,Tg(tetO-Kras*G12D)#Rdp/0
  http://metadb.riken.jp/0009151I129S1Sv129X1SvJC57BL6FVBNGtROSA26Sortm1rtTAEGFPNagyGtROSA26SorPtf1atm11creCvwPtf1aTgtetOKrasG12DRdp0GtROSA26SorPtf1aTgtetOKrasG12DRdpPtf1atm11creCvwGtROSA26Sortm1rtTAEGFPNagy
• increased pancreatic ductal adenocarcinoma incidence_Gt(ROSA)26Sor<tm1(rtTA,EGFP)Nagy>/Gt(ROSA)26Sor<+>,Ptf1a<tm1.1(cre)Cvw>/Ptf1a<+>,Tg(tetO-Kras*G12D)#Rdp/0,Trp53<tm1Brn>/Trp53<tm1Brn>
  http://metadb.riken.jp/0009151I129P2OlaHsd129S1Sv129X1SvJC57BL6FVBNGtROSA26Sortm1rtTAEGFPNagyGtROSA26SorPtf1atm11creCvwPtf1aTgtetOKrasG12DRdp0Trp53tm1BrnTrp53tm1BrnPtf1atm11creCvwGtROSA26Sortm1rtTAEGFPNagyPtf1aTrp53tm1BrnTgtetOKrasG12DRdpGtROSA26Sor

class

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-Kras*G12D)#Rdp
  http://metadb.riken.jp/db/mgi_rdf/MGI:5648530