Janssen. Daly, et.al., Altered Ig hypermutation pattern and frequency in complementary mouse models of DNA polymerase ζ activity., Journal of immunology (Baltimore, Md. : 1950), 2012, 188

http://rdf.ncbi.nlm.nih.gov/pubmed/22547703

Janssen. Daly, et.al., Altered Ig hypermutation pattern and frequency in complementary mouse models of DNA polymerase ζ activity., Journal of immunology (Baltimore, Md. : 1950), 2012, 188

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Rev3l<tm1.1Kunk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5442607
• Rev3l<tm1.1Diaz>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5442606

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal class switch recombination_Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>,Cd19<tm1(cre)Cgn>/Cd19<+>,Rev3l<tm1.1Diaz>/Rev3l<tm1.1Diaz>
  http://metadb.riken.jp/0004816I129P2OlaHsd129X1SvJBALBcC57BL6C57BL6NTacGtROSA26Sortm1EYFPCosGtROSA26SorCd19tm1creCgnCd19Rev3ltm11DiazRev3ltm11DiazCd19GtROSA26SorRev3ltm11DiazCd19tm1creCgnGtROSA26Sortm1EYFPCos
• decreased B cell proliferation_Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>,Cd19<tm1(cre)Cgn>/Cd19<+>,Rev3l<tm1.1Diaz>/Rev3l<tm1.1Diaz>
  http://metadb.riken.jp/0005093I129P2OlaHsd129X1SvJBALBcC57BL6C57BL6NTacGtROSA26Sortm1EYFPCosGtROSA26SorCd19tm1creCgnCd19Rev3ltm11DiazRev3ltm11DiazCd19GtROSA26SorRev3ltm11DiazCd19tm1creCgnGtROSA26Sortm1EYFPCos
• abnormal somatic hypermutation frequency_Rev3l<tm1.1Kunk>/Rev3l<tm1.1Kunk>
  http://metadb.riken.jp/0004815IC57BL6Rev3ltm11KunkRev3ltm11KunkRev3ltm11Kunk
• abnormal somatic hypermutation frequency_Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>,Cd19<tm1(cre)Cgn>/Cd19<+>,Rev3l<tm1.1Diaz>/Rev3l<tm1.1Diaz>
  http://metadb.riken.jp/0004815I129P2OlaHsd129X1SvJBALBcC57BL6C57BL6NTacGtROSA26Sortm1EYFPCosGtROSA26SorCd19tm1creCgnCd19Rev3ltm11DiazRev3ltm11DiazCd19GtROSA26SorRev3ltm11DiazCd19tm1creCgnGtROSA26Sortm1EYFPCos

class

http://purl.org/net/cito/citesAsAuthority

• Rev3l<tm1.1Kunk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5442607
• Rev3l<tm1.1Diaz>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5442606