Bart A. Westerman, et.al., GFAP-Cre-mediated transgenic activation of Bmi1 results in pituitary tumors., PloS one, 2012, 7

http://rdf.ncbi.nlm.nih.gov/pubmed/22574128

Bart A. Westerman, et.al., GFAP-Cre-mediated transgenic activation of Bmi1 results in pituitary tumors., PloS one, 2012, 7

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm2(CMV-Bmi1,EGFP)Nki>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4398914

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased carcinoma incidence_Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Gfap-cre)2Brn/0
  http://metadb.riken.jp/0002038I129129P2OlaHsdFVBNRb1tm2BrnRb1tm2BrnTrp53tm1BrnTrp53tm1BrnTgGfapcre2Brn0Rb1tm2BrnTgGfapcre2BrnTrp53tm1Brn
• premature death_Gt(ROSA)26Sor<tm1(CAG-Bmi1,-EGFP)Nki>/Gt(ROSA)26Sor<+>,Tg(Gfap-cre)2Brn/0
  http://metadb.riken.jp/0002083EI129P2OlaHsdFVBNorI129P2OlaHsdC57BL6FVBNGtROSA26Sortm1CAGBmi1EGFPNkiGtROSA26SorTgGfapcre2Brn0GtROSA26Sortm1CAGBmi1EGFPNkiTgGfapcre2BrnGtROSA26Sor
• increased pituitary gland tumor incidence_Rb1<tm2Brn>/Rb1<tm2Brn>,Tg(Gfap-cre)2Brn/0
  http://metadb.riken.jp/0010320I129FVBNRb1tm2BrnRb1tm2BrnTgGfapcre2Brn0TgGfapcre2BrnRb1tm2Brn
• premature death_Rb1<tm2Brn>/Rb1<tm2Brn>,Tg(Gfap-cre)2Brn/0
  http://metadb.riken.jp/0002083I129FVBNRb1tm2BrnRb1tm2BrnTgGfapcre2Brn0TgGfapcre2BrnRb1tm2Brn
• increased tumor incidence_Gt(ROSA)26Sor<tm1(CAG-Bmi1,-EGFP)Nki>/Gt(ROSA)26Sor<+>,Tg(Gfap-cre)2Brn/0
  http://metadb.riken.jp/0002020EI129P2OlaHsdFVBNorI129P2OlaHsdC57BL6FVBNGtROSA26Sortm1CAGBmi1EGFPNkiGtROSA26SorTgGfapcre2Brn0GtROSA26Sortm1CAGBmi1EGFPNkiTgGfapcre2BrnGtROSA26Sor
• increased medulloblastoma incidence_Gt(ROSA)26Sor<tm1(CAG-Bmi1,-EGFP)Nki>/Gt(ROSA)26Sor<+>,Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Gfap-cre)2Brn/0
  http://metadb.riken.jp/0006283EI129129P2OlaHsdFVBNorI129129P2OlaHsdC57BL6FVBNGtROSA26Sortm1CAGBmi1EGFPNkiGtROSA26SorRb1tm2BrnRb1tm2BrnTrp53tm1BrnTrp53tm1BrnTgGfapcre2Brn0Rb1tm2BrnGtROSA26Sortm1CAGBmi1EGFPNkiTrp53tm1BrnTgGfapcre2BrnGtROSA26Sor
• increased carcinoma incidence_Rb1<tm2Brn>/Rb1<tm2Brn>,Tg(Gfap-cre)2Brn/0
  http://metadb.riken.jp/0002038I129FVBNRb1tm2BrnRb1tm2BrnTgGfapcre2Brn0TgGfapcre2BrnRb1tm2Brn
• increased pituitary gland tumor incidence_Gt(ROSA)26Sor<tm1(CAG-Bmi1,-EGFP)Nki>/Gt(ROSA)26Sor<+>,Tg(Gfap-cre)2Brn/0
  http://metadb.riken.jp/0010320EI129P2OlaHsdFVBNorI129P2OlaHsdC57BL6FVBNGtROSA26Sortm1CAGBmi1EGFPNkiGtROSA26SorTgGfapcre2Brn0GtROSA26Sortm1CAGBmi1EGFPNkiTgGfapcre2BrnGtROSA26Sor
• increased pituitary gland tumor incidence_Gt(ROSA)26Sor<tm1(CAG-Bmi1,-EGFP)Nki>/Gt(ROSA)26Sor<+>,Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Gfap-cre)2Brn/0
  http://metadb.riken.jp/0010320EI129129P2OlaHsdFVBNorI129129P2OlaHsdC57BL6FVBNGtROSA26Sortm1CAGBmi1EGFPNkiGtROSA26SorRb1tm2BrnRb1tm2BrnTrp53tm1BrnTrp53tm1BrnTgGfapcre2Brn0Rb1tm2BrnGtROSA26Sortm1CAGBmi1EGFPNkiTrp53tm1BrnTgGfapcre2BrnGtROSA26Sor
• premature death_Gt(ROSA)26Sor<tm1(CAG-Bmi1,-EGFP)Nki>/Gt(ROSA)26Sor<+>,Rb1<tm2Brn>/Rb1<tm2Brn>,Tg(Gfap-cre)2Brn/0
  http://metadb.riken.jp/0002083EI129129P2OlaHsdFVBNorI129129P2OlaHsdC57BL6FVBNGtROSA26Sortm1CAGBmi1EGFPNkiGtROSA26SorRb1tm2BrnRb1tm2BrnTgGfapcre2Brn0GtROSA26SorTgGfapcre2BrnGtROSA26Sortm1CAGBmi1EGFPNkiRb1tm2Brn
• increased medulloblastoma incidence_Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Gfap-cre)2Brn/0
  http://metadb.riken.jp/0006283I129129P2OlaHsdFVBNRb1tm2BrnRb1tm2BrnTrp53tm1BrnTrp53tm1BrnTgGfapcre2Brn0Rb1tm2BrnTgGfapcre2BrnTrp53tm1Brn
• increased carcinoma incidence_Gt(ROSA)26Sor<tm1(CAG-Bmi1,-EGFP)Nki>/Gt(ROSA)26Sor<+>,Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Gfap-cre)2Brn/0
  http://metadb.riken.jp/0002038EI129129P2OlaHsdFVBNorI129129P2OlaHsdC57BL6FVBNGtROSA26Sortm1CAGBmi1EGFPNkiGtROSA26SorRb1tm2BrnRb1tm2BrnTrp53tm1BrnTrp53tm1BrnTgGfapcre2Brn0Rb1tm2BrnGtROSA26Sortm1CAGBmi1EGFPNkiTrp53tm1BrnTgGfapcre2BrnGtROSA26Sor
• increased pituitary gland tumor incidence_Gt(ROSA)26Sor<tm1(CAG-Bmi1,-EGFP)Nki>/Gt(ROSA)26Sor<+>,Rb1<tm2Brn>/Rb1<tm2Brn>,Tg(Gfap-cre)2Brn/0
  http://metadb.riken.jp/0010320EI129129P2OlaHsdFVBNorI129129P2OlaHsdC57BL6FVBNGtROSA26Sortm1CAGBmi1EGFPNkiGtROSA26SorRb1tm2BrnRb1tm2BrnTgGfapcre2Brn0GtROSA26SorTgGfapcre2BrnGtROSA26Sortm1CAGBmi1EGFPNkiRb1tm2Brn
• increased pituitary gland tumor incidence_Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Gfap-cre)2Brn/0
  http://metadb.riken.jp/0010320I129129P2OlaHsdFVBNRb1tm2BrnRb1tm2BrnTrp53tm1BrnTrp53tm1BrnTgGfapcre2Brn0Rb1tm2BrnTgGfapcre2BrnTrp53tm1Brn
• increased mammary gland tumor incidence_Gt(ROSA)26Sor<tm1(CAG-Bmi1,-EGFP)Nki>/Gt(ROSA)26Sor<+>,Tg(Gfap-cre)2Brn/0
  http://metadb.riken.jp/0010299EI129P2OlaHsdFVBNorI129P2OlaHsdC57BL6FVBNGtROSA26Sortm1CAGBmi1EGFPNkiGtROSA26SorTgGfapcre2Brn0GtROSA26Sortm1CAGBmi1EGFPNkiTgGfapcre2BrnGtROSA26Sor
• increased papilloma incidence_Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Gfap-cre)2Brn/0
  http://metadb.riken.jp/0002014I129129P2OlaHsdFVBNRb1tm2BrnRb1tm2BrnTrp53tm1BrnTrp53tm1BrnTgGfapcre2Brn0Rb1tm2BrnTgGfapcre2BrnTrp53tm1Brn

class

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm2(CMV-Bmi1,EGFP)Nki>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4398914