Paul R. Mittelstadt, et.al., Thymocyte responsiveness to endogenous glucocorticoids is required for immunological fitness., The Journal of clinical investigation, 2012, 122

http://rdf.ncbi.nlm.nih.gov/pubmed/22653054

Paul R. Mittelstadt, et.al., Thymocyte responsiveness to endogenous glucocorticoids is required for immunological fitness., The Journal of clinical investigation, 2012, 122

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Nr3c1<tm1.1Jda>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5447468

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased double-positive T cell number_Nr3c1<tm1.1Jda>/Nr3c1<tm1.1Jda>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0005092B6CgNr3c1tm11JdaTgLckcre548JxmNr3c1tm11JdaNr3c1tm11JdaTgLckcre548Jxm0Nr3c1tm11JdaTgLckcre548Jxm
• decreased thymocyte apoptosis_Nr3c1<tm1.1Jda>/Nr3c1<tm1.1Jda>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0009542B6CgNr3c1tm11JdaTgLckcre548JxmNr3c1tm11JdaNr3c1tm11JdaTgLckcre548Jxm0Nr3c1tm11JdaTgLckcre548Jxm
• decreased single-positive T cell number_Nr3c1<tm1.1Jda>/Nr3c1<tm1.1Jda>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0008083B6CgNr3c1tm11JdaTgLckcre548JxmNr3c1tm11JdaNr3c1tm11JdaTgLckcre548Jxm0Nr3c1tm11JdaTgLckcre548Jxm
• decreased double-positive T cell number_Nr3c1<tm1.1Jda>/Nr3c1<tm1.1Jda>,Rag2<tm1.1Cgn>/Rag2<tm1.1Cgn>,Tg(Lck-cre)548Jxm/0,Tg(TcrAND)53Hed/0
  http://metadb.riken.jp/0005092B6CgRag2tm11CgnNr3c1tm11JdaTgLckcre548JxmTgTcrAND53HedNr3c1tm11JdaNr3c1tm11JdaRag2tm11CgnRag2tm11CgnTgLckcre548Jxm0TgTcrAND53Hed0Rag2tm11CgnTgLckcre548JxmNr3c1tm11JdaTgTcrAND53Hed
• decreased thymocyte apoptosis_Nr3c1<tm1.1Jda>/Nr3c1<+>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0009542B6CgNr3c1tm11JdaTgLckcre548JxmNr3c1tm11JdaNr3c1TgLckcre548Jxm0Nr3c1Nr3c1tm11JdaTgLckcre548Jxm
• decreased CD8-positive, alpha-beta T cell number_Nr3c1<tm1.1Jda>/Nr3c1<tm1.1Jda>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0008079B6CgNr3c1tm11JdaTgLckcre548JxmNr3c1tm11JdaNr3c1tm11JdaTgLckcre548Jxm0Nr3c1tm11JdaTgLckcre548Jxm
• decreased double-positive T cell number_Nr3c1<tm1.1Jda>/Nr3c1<tm1.1Jda>,Tcra<tm1Mom>/Tcra<tm1Mom>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0005092B6CgTcratm1MomNr3c1tm11JdaTgLckcre548JxmNr3c1tm11JdaNr3c1tm11JdaTcratm1MomTcratm1MomTgLckcre548Jxm0Nr3c1tm11JdaTgLckcre548JxmTcratm1Mom
• thymus hypoplasia_Nr3c1<tm1.1Jda>/Nr3c1<tm1.1Jda>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0001823B6CgNr3c1tm11JdaTgLckcre548JxmNr3c1tm11JdaNr3c1tm11JdaTgLckcre548Jxm0Nr3c1tm11JdaTgLckcre548Jxm
• abnormal humoral immune response_Nr3c1<tm1.1Jda>/Nr3c1<tm1.1Jda>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0001800B6CgNr3c1tm11JdaTgLckcre548JxmNr3c1tm11JdaNr3c1tm11JdaTgLckcre548Jxm0Nr3c1tm11JdaTgLckcre548Jxm
• decreased CD4-positive, alpha beta T cell number_Nr3c1<tm1.1Jda>/Nr3c1<tm1.1Jda>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0008075B6CgNr3c1tm11JdaTgLckcre548JxmNr3c1tm11JdaNr3c1tm11JdaTgLckcre548Jxm0Nr3c1tm11JdaTgLckcre548Jxm

class

http://purl.org/net/cito/citesAsAuthority

• Nr3c1<tm1.1Jda>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5447468