Jingqiang. Wang, et.al., B-Raf activation cooperates with PTEN loss to drive c-Myc expression in advanced prostate cancer., Cancer research, 2012, 72

http://rdf.ncbi.nlm.nih.gov/pubmed/22836754

Jingqiang. Wang, et.al., B-Raf activation cooperates with PTEN loss to drive c-Myc expression in advanced prostate cancer., Cancer research, 2012, 72

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased metastatic potential_Braf<tm1Mmcm>/Braf<tm1Mmcm>,Nkx3-1<tm4(cre/ERT2)Mms>/Nkx3-1<+>,Pten<tm1Hwu>/Pten<+>
  http://metadb.riken.jp/0001272I129P2OlaHsd129S4SvJae129S6SvEvTacC57BL6Braftm1MmcmBraftm1MmcmNkx31tm4creERT2MmsNkx31Ptentm1HwuPtenNkx31PtenPtentm1HwuNkx31tm4creERT2MmsBraftm1Mmcm
• premature death_Braf<tm1Mmcm>/Braf<tm1Mmcm>,Nkx3-1<tm4(cre/ERT2)Mms>/Nkx3-1<+>,Pten<tm1Hwu>/Pten<+>
  http://metadb.riken.jp/0002083I129P2OlaHsd129S4SvJae129S6SvEvTacC57BL6Braftm1MmcmBraftm1MmcmNkx31tm4creERT2MmsNkx31Ptentm1HwuPtenNkx31PtenPtentm1HwuNkx31tm4creERT2MmsBraftm1Mmcm
• increased prostate intraepithelial neoplasia incidence_Braf<tm1Mmcm>/Braf<tm1Mmcm>,Nkx3-1<tm4(cre/ERT2)Mms>/Nkx3-1<+>,Pten<tm1Hwu>/Pten<+>
  http://metadb.riken.jp/0009219I129P2OlaHsd129S4SvJae129S6SvEvTacC57BL6Braftm1MmcmBraftm1MmcmNkx31tm4creERT2MmsNkx31Ptentm1HwuPtenNkx31PtenPtentm1HwuNkx31tm4creERT2MmsBraftm1Mmcm
• increased prostate intraepithelial neoplasia incidence_Nkx3-1<tm4(cre/ERT2)Mms>/Nkx3-1<+>,Pten<tm1Hwu>/Pten<tm1Hwu>
  http://metadb.riken.jp/0009219I129S4SvJae129S6SvEvTacC57BL6Nkx31tm4creERT2MmsNkx31Ptentm1HwuPtentm1HwuNkx31tm4creERT2MmsPtentm1HwuNkx31
• increased prostate gland adenocarcinoma incidence_Braf<tm1Mmcm>/Braf<tm1Mmcm>,Nkx3-1<tm4(cre/ERT2)Mms>/Nkx3-1<+>,Pten<tm1Hwu>/Pten<+>
  http://metadb.riken.jp/0009220I129P2OlaHsd129S4SvJae129S6SvEvTacC57BL6Braftm1MmcmBraftm1MmcmNkx31tm4creERT2MmsNkx31Ptentm1HwuPtenNkx31PtenPtentm1HwuNkx31tm4creERT2MmsBraftm1Mmcm
• increased prostate gland tumor incidence_Braf<tm1Mmcm>/Braf<tm1Mmcm>,Nkx3-1<tm4(cre/ERT2)Mms>/Nkx3-1<+>,Pten<tm1Hwu>/Pten<+>
  http://metadb.riken.jp/0010357I129P2OlaHsd129S4SvJae129S6SvEvTacC57BL6Braftm1MmcmBraftm1MmcmNkx31tm4creERT2MmsNkx31Ptentm1HwuPtenNkx31PtenPtentm1HwuNkx31tm4creERT2MmsBraftm1Mmcm