Andrey N. Kuzmichev, et.al., Sox2 acts through Sox21 to regulate transcription in pluripotent and differentiated cells., Current biology : CB, 2012, 22

http://rdf.ncbi.nlm.nih.gov/pubmed/22902753

Andrey N. Kuzmichev, et.al., Sox2 acts through Sox21 to regulate transcription in pluripotent and differentiated cells., Current biology : CB, 2012, 22

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Col1a1<tm1(tetO-SOX2)Mjm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5508552

class

http://purl.org/net/cito/citesAsAuthority

• Col1a1<tm1(tetO-SOX2)Mjm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5508552

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• ectopic Paneth cells_Col1a1<tm1(tetO-SOX2)Mjm>/Col1a1<+>,Gt(ROSA)26Sor<tm1(tTA)Roos>/Gt(ROSA)26Sor<+>,Lgr5<tm1(cre/ERT2)Cle>/Lgr5<+>
  http://metadb.riken.jp/0014077I129P2OlaHsd129S4SvJaeC57BL6DBA2JCol1a1tm1tetOSOX2MjmCol1a1GtROSA26Sortm1tTARoosGtROSA26SorLgr5tm1creERT2CleLgr5Lgr5tm1creERT2CleGtROSA26SorLgr5Col1a1Col1a1tm1tetOSOX2MjmGtROSA26Sortm1tTARoos
• abnormal intestine physiology_Col1a1<tm1(tetO-SOX2)Mjm>/Col1a1<+>,Gt(ROSA)26Sor<tm1(tTA)Roos>/Gt(ROSA)26Sor<+>,Lgr5<tm1(cre/ERT2)Cle>/Lgr5<+>
  http://metadb.riken.jp/0010155I129P2OlaHsd129S4SvJaeC57BL6DBA2JCol1a1tm1tetOSOX2MjmCol1a1GtROSA26Sortm1tTARoosGtROSA26SorLgr5tm1creERT2CleLgr5Lgr5tm1creERT2CleGtROSA26SorLgr5Col1a1Col1a1tm1tetOSOX2MjmGtROSA26Sortm1tTARoos
• abnormal small intestine crypts of Lieberkuhn morphology_Col1a1<tm2(tetO-Pou5f1)Jae>/Col1a1<+>,Gt(ROSA)26Sor<tm1(tTA)Roos>/Gt(ROSA)26Sor<+>,Lgr5<tm1(cre/ERT2)Cle>/Lgr5<+>
  http://metadb.riken.jp/0004841I129P2OlaHsd129S4SvJaeC57BL6DBA2JCol1a1tm2tetOPou5f1JaeCol1a1GtROSA26Sortm1tTARoosGtROSA26SorLgr5tm1creERT2CleLgr5GtROSA26Sortm1tTARoosCol1a1tm2tetOPou5f1JaeCol1a1Lgr5tm1creERT2CleGtROSA26SorLgr5
• increased cell proliferation_Col1a1<tm2(tetO-Pou5f1)Jae>/Col1a1<+>,Gt(ROSA)26Sor<tm1(tTA)Roos>/Gt(ROSA)26Sor<+>,Lgr5<tm1(cre/ERT2)Cle>/Lgr5<+>
  http://metadb.riken.jp/0000351I129P2OlaHsd129S4SvJaeC57BL6DBA2JCol1a1tm2tetOPou5f1JaeCol1a1GtROSA26Sortm1tTARoosGtROSA26SorLgr5tm1creERT2CleLgr5GtROSA26Sortm1tTARoosCol1a1tm2tetOPou5f1JaeCol1a1Lgr5tm1creERT2CleGtROSA26SorLgr5
• abnormal ileum crypts of Lieberkuhn morphology_Col1a1<tm1(tetO-SOX2)Mjm>/Col1a1<+>,Gt(ROSA)26Sor<tm1(tTA)Roos>/Gt(ROSA)26Sor<+>,Lgr5<tm1(cre/ERT2)Cle>/Lgr5<+>
  http://metadb.riken.jp/0013481I129P2OlaHsd129S4SvJaeC57BL6DBA2JCol1a1tm1tetOSOX2MjmCol1a1GtROSA26Sortm1tTARoosGtROSA26SorLgr5tm1creERT2CleLgr5Lgr5tm1creERT2CleGtROSA26SorLgr5Col1a1Col1a1tm1tetOSOX2MjmGtROSA26Sortm1tTARoos
• abnormal intestine physiology_Col1a1<tm2(tetO-Pou5f1)Jae>/Col1a1<+>,Gt(ROSA)26Sor<tm1(tTA)Roos>/Gt(ROSA)26Sor<+>,Lgr5<tm1(cre/ERT2)Cle>/Lgr5<+>
  http://metadb.riken.jp/0010155I129P2OlaHsd129S4SvJaeC57BL6DBA2JCol1a1tm2tetOPou5f1JaeCol1a1GtROSA26Sortm1tTARoosGtROSA26SorLgr5tm1creERT2CleLgr5GtROSA26Sortm1tTARoosCol1a1tm2tetOPou5f1JaeCol1a1Lgr5tm1creERT2CleGtROSA26SorLgr5
• increased cell proliferation_Col1a1<tm1(tetO-SOX2)Mjm>/Col1a1<+>,Gt(ROSA)26Sor<tm1(tTA)Roos>/Gt(ROSA)26Sor<+>,Lgr5<tm1(cre/ERT2)Cle>/Lgr5<+>
  http://metadb.riken.jp/0000351I129P2OlaHsd129S4SvJaeC57BL6DBA2JCol1a1tm1tetOSOX2MjmCol1a1GtROSA26Sortm1tTARoosGtROSA26SorLgr5tm1creERT2CleLgr5Lgr5tm1creERT2CleGtROSA26SorLgr5Col1a1Col1a1tm1tetOSOX2MjmGtROSA26Sortm1tTARoos