Monique C M. Balemans, et.al., Hippocampal dysfunction in the Euchromatin histone methyltransferase 1 heterozygous knockout mouse model for Kleefstra syndrome., Human molecular genetics, 2013, 22

http://rdf.ncbi.nlm.nih.gov/pubmed/23175442

Monique C M. Balemans, et.al., Hippocampal dysfunction in the Euchromatin histone methyltransferase 1 heterozygous knockout mouse model for Kleefstra syndrome., Human molecular genetics, 2013, 22

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal associative learning_Ehmt1<tm1Yshk>/Ehmt1<+>
  http://metadb.riken.jp/0002062IC57BL6JC57BL6NCrljCBAJNCrljEhmt1tm1YshkEhmt1Ehmt1tm1YshkEhmt1
• abnormal response to novel object_Ehmt1<tm1Yshk>/Ehmt1<+>
  http://metadb.riken.jp/0003461IC57BL6JC57BL6NCrljCBAJNCrljEhmt1tm1YshkEhmt1Ehmt1tm1YshkEhmt1
• impaired cued conditioning behavior_Ehmt1<tm1Yshk>/Ehmt1<+>
  http://metadb.riken.jp/0009456IC57BL6JC57BL6NCrljCBAJNCrljEhmt1tm1YshkEhmt1Ehmt1tm1YshkEhmt1
• impaired synaptic plasticity_Ehmt1<tm1Yshk>/Ehmt1<+>
  http://metadb.riken.jp/0001900IC57BL6JC57BL6NCrljCBAJNCrljEhmt1tm1YshkEhmt1Ehmt1tm1YshkEhmt1
• abnormal miniature excitatory postsynaptic currents_Ehmt1<tm1Yshk>/Ehmt1<+>
  http://metadb.riken.jp/0004753IC57BL6JC57BL6NCrljCBAJNCrljEhmt1tm1YshkEhmt1Ehmt1tm1YshkEhmt1
• enhanced paired-pulse facilitation_Ehmt1<tm1Yshk>/Ehmt1<+>
  http://metadb.riken.jp/0002919IC57BL6JC57BL6NCrljCBAJNCrljEhmt1tm1YshkEhmt1Ehmt1tm1YshkEhmt1
• abnormal object recognition memory_Ehmt1<tm1Yshk>/Ehmt1<+>
  http://metadb.riken.jp/0001458IC57BL6JC57BL6NCrljCBAJNCrljEhmt1tm1YshkEhmt1Ehmt1tm1YshkEhmt1
• impaired contextual conditioning behavior_Ehmt1<tm1Yshk>/Ehmt1<+>
  http://metadb.riken.jp/0009454IC57BL6JC57BL6NCrljCBAJNCrljEhmt1tm1YshkEhmt1Ehmt1tm1YshkEhmt1
• abnormal dendritic spine morphology_Ehmt1<tm1Yshk>/Ehmt1<+>
  http://metadb.riken.jp/0009936IC57BL6JC57BL6NCrljCBAJNCrljEhmt1tm1YshkEhmt1Ehmt1tm1YshkEhmt1
• abnormal hippocampus pyramidal cell morphology_Ehmt1<tm1Yshk>/Ehmt1<+>
  http://metadb.riken.jp/0009940IC57BL6JC57BL6NCrljCBAJNCrljEhmt1tm1YshkEhmt1Ehmt1tm1YshkEhmt1
• abnormal dendrite morphology_Ehmt1<tm1Yshk>/Ehmt1<+>
  http://metadb.riken.jp/0008143IC57BL6JC57BL6NCrljCBAJNCrljEhmt1tm1YshkEhmt1Ehmt1tm1YshkEhmt1
• abnormal sensory capabilities/reflexes/nociception_Ehmt1<tm1Yshk>/Ehmt1<+>
  http://metadb.riken.jp/0002067IC57BL6JC57BL6NCrljCBAJNCrljEhmt1tm1YshkEhmt1Ehmt1tm1YshkEhmt1
• increased startle reflex_Ehmt1<tm1Yshk>/Ehmt1<+>
  http://metadb.riken.jp/0001488IC57BL6JC57BL6NCrljCBAJNCrljEhmt1tm1YshkEhmt1Ehmt1tm1YshkEhmt1

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• impaired cued conditioning behavior in RBRC01422
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002718
• enhanced paired-pulse facilitation in RBRC01422
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002712
• impaired synaptic plasticity in RBRC01422
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002707
• abnormal sensory capabilities/reflexes/nociception in RBRC01422
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002709
• abnormal dendritic spine morphology in RBRC01422
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002719
• abnormal dendrite morphology in RBRC01422
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002716
• abnormal response to novel object in RBRC01422
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002713
• abnormal associative learning in RBRC01422
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002708
• abnormal miniature excitatory postsynaptic currents in RBRC01422
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002715
• increased startle reflex in RBRC01422
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002705
• abnormal hippocampus pyramidal cell morphology in RBRC01422
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002720
• impaired contextual conditioning behavior in RBRC01422
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002717
• abnormal object recognition memory in RBRC01422
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002704