Jianbin. Huang, et.al., Angiotensin-converting enzyme-induced activation of local angiotensin signaling is required for ascending aortic aneurysms in fibulin-4-deficient mice., Science translational medicine, 2013, 5

http://rdf.ncbi.nlm.nih.gov/pubmed/23636094

Jianbin. Huang, et.al., Angiotensin-converting enzyme-induced activation of local angiotensin signaling is required for ascending aortic aneurysms in fibulin-4-deficient mice., Science translational medicine, 2013, 5

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal aorta smooth muscle morphology_Efemp2<tm1.1Hiya>/Efemp2<tm1.2Hiya>,Tg(Tagln-cre)1Her/0
  http://metadb.riken.jp/0009865I129S6SvEvTacC57BL6SJLEfemp2tm11HiyaEfemp2tm12HiyaTgTaglncre1Her0TgTaglncre1HerEfemp2tm12HiyaEfemp2tm11Hiya
• increased aorta wall thickness_Agtr2<tm1Tin>/Y,Efemp2<tm1.1Hiya>/Efemp2<tm1.2Hiya>,Tg(Tagln-cre)1Her/0
  http://metadb.riken.jp/0010996I129P2OlaHsd129S6SvEvTacC57BL6SJLAgtr2tm1TinYEfemp2tm11HiyaEfemp2tm12HiyaTgTaglncre1Her0TgTaglncre1HerAgtr2tm1TinEfemp2tm12HiyaEfemp2tm11Hiya
• abnormal aorta wall morphology_Efemp2<tm1.1Hiya>/Efemp2<tm1.2Hiya>,Tg(Tagln-cre)1Her/0
  http://metadb.riken.jp/0009866I129S6SvEvTacC57BL6SJLEfemp2tm11HiyaEfemp2tm12HiyaTgTaglncre1Her0TgTaglncre1HerEfemp2tm12HiyaEfemp2tm11Hiya
• increased pulse pressure_Efemp2<tm1.1Hiya>/Efemp2<tm1.2Hiya>,Tg(Tagln-cre)1Her/0
  http://metadb.riken.jp/0006265I129S6SvEvTacC57BL6SJLEfemp2tm11HiyaEfemp2tm12HiyaTgTaglncre1Her0TgTaglncre1HerEfemp2tm12HiyaEfemp2tm11Hiya
• abnormal blood vessel physiology_Efemp2<tm1.1Hiya>/Efemp2<tm1.2Hiya>,Tg(Tagln-cre)1Her/0
  http://metadb.riken.jp/0000249I129S6SvEvTacC57BL6SJLEfemp2tm11HiyaEfemp2tm12HiyaTgTaglncre1Her0TgTaglncre1HerEfemp2tm12HiyaEfemp2tm11Hiya
• ascending aorta aneurysm_Agtr2<tm1Tin>/Y,Efemp2<tm1.1Hiya>/Efemp2<tm1.2Hiya>,Tg(Tagln-cre)1Her/0
  http://metadb.riken.jp/0010661I129P2OlaHsd129S6SvEvTacC57BL6SJLAgtr2tm1TinYEfemp2tm11HiyaEfemp2tm12HiyaTgTaglncre1Her0TgTaglncre1HerAgtr2tm1TinEfemp2tm12HiyaEfemp2tm11Hiya
• decreased systemic arterial diastolic blood pressure_Efemp2<tm1.1Hiya>/Efemp2<tm1.2Hiya>,Tg(Tagln-cre)1Her/0
  http://metadb.riken.jp/0006263I129S6SvEvTacC57BL6SJLEfemp2tm11HiyaEfemp2tm12HiyaTgTaglncre1Her0TgTaglncre1HerEfemp2tm12HiyaEfemp2tm11Hiya
• ascending aorta dilation_Efemp2<tm1.1Hiya>/Efemp2<tm1.2Hiya>,Tg(Tagln-cre)1Her/0
  http://metadb.riken.jp/0010470I129S6SvEvTacC57BL6SJLEfemp2tm11HiyaEfemp2tm12HiyaTgTaglncre1Her0TgTaglncre1HerEfemp2tm12HiyaEfemp2tm11Hiya
• ascending aorta aneurysm_Efemp2<tm1.1Hiya>/Efemp2<tm1.2Hiya>,Tg(Tagln-cre)1Her/0
  http://metadb.riken.jp/0010661I129S6SvEvTacC57BL6SJLEfemp2tm11HiyaEfemp2tm12HiyaTgTaglncre1Her0TgTaglncre1HerEfemp2tm12HiyaEfemp2tm11Hiya
• abnormal ascending aorta morphology_Efemp2<tm1.1Hiya>/Efemp2<tm1.2Hiya>,Tg(Tagln-cre)1Her/0
  http://metadb.riken.jp/0009867I129S6SvEvTacC57BL6SJLEfemp2tm11HiyaEfemp2tm12HiyaTgTaglncre1Her0TgTaglncre1HerEfemp2tm12HiyaEfemp2tm11Hiya
• increased aorta wall thickness_Agtr1a<tm1Unc>/Agtr1a<tm1Unc>,Efemp2<tm1.1Hiya>/Efemp2<tm1.2Hiya>,Tg(Tagln-cre)1Her/0
  http://metadb.riken.jp/0010996I129P2OlaHsd129S6SvEvTacC57BL6SJLAgtr1atm1UncAgtr1atm1UncEfemp2tm11HiyaEfemp2tm12HiyaTgTaglncre1Her0TgTaglncre1HerEfemp2tm12HiyaAgtr1atm1UncEfemp2tm11Hiya
• abnormal aorta smooth muscle morphology_Agtr2<tm1Tin>/Y,Efemp2<tm1.1Hiya>/Efemp2<tm1.2Hiya>,Tg(Tagln-cre)1Her/0
  http://metadb.riken.jp/0009865I129P2OlaHsd129S6SvEvTacC57BL6SJLAgtr2tm1TinYEfemp2tm11HiyaEfemp2tm12HiyaTgTaglncre1Her0TgTaglncre1HerAgtr2tm1TinEfemp2tm12HiyaEfemp2tm11Hiya