Yinming. Liang, et.al., The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells., Nature immunology, 2013, 14

http://rdf.ncbi.nlm.nih.gov/pubmed/23793062

Yinming. Liang, et.al., The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells., Nature immunology, 2013, 14

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Carmil2<bas>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5547539
• Lat<tm8Mal>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5547536

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• enlarged thymus_Carmil2<bas>/Carmil2<bas>
  http://metadb.riken.jp/0000709IC3HeBFeJC57BL6Carmil2basCarmil2basCarmil2bas
• enlarged thymus_Cd28<tm1Mak>/Cd28<tm1Mak>
  http://metadb.riken.jp/0000709I129S2SvPasCd28tm1MakCd28tm1MakCd28tm1Mak
• decreased regulatory T cell number_Carmil2<bas>/Carmil2<bas>
  http://metadb.riken.jp/0004974IC3HeBFeJC57BL6Carmil2basCarmil2basCarmil2bas
• abnormal immune system morphology_Lat<tm8Mal>/Lat<tm8Mal>
  http://metadb.riken.jp/0000685IC57BL6Lattm8MalLattm8MalLattm8Mal
• increased T-helper 2 cell number_Lat<tm8Mal>/Lat<tm8Mal>
  http://metadb.riken.jp/0008090IC57BL6Lattm8MalLattm8MalLattm8Mal
• decreased interferon-gamma secretion_Cd28<tm1Mak>/Cd28<tm1Mak>
  http://metadb.riken.jp/0008567I129S2SvPasCd28tm1MakCd28tm1MakCd28tm1Mak
• decreased T cell proliferation_Carmil2<bas>/Carmil2<tm1a(KOMP)Mbp>
  http://metadb.riken.jp/0005095IC3HeBFeJC57BL6C57BL6NCarmil2basCarmil2tm1aKOMPMbpCarmil2tm1aKOMPMbpCarmil2bas
• abnormal lymphopoiesis_Lat<tm8Mal>/Lat<tm8Mal>
  http://metadb.riken.jp/0002401IC57BL6Lattm8MalLattm8MalLattm8Mal
• decreased interleukin-2 secretion_Carmil2<bas>/Carmil2<bas>
  http://metadb.riken.jp/0008688IC3HeBFeJC57BL6Carmil2basCarmil2basCarmil2bas
• decreased regulatory T cell number_Cd80<tm1Shr>/Cd80<tm1Shr>,Cd86<tm2Shr>/Cd86<tm2Shr>
  http://metadb.riken.jp/0004974I129S4SvJaeCd80tm1ShrCd80tm1ShrCd86tm2ShrCd86tm2ShrCd80tm1ShrCd86tm2Shr
• abnormal immune system physiology_Lat<tm8Mal>/Lat<tm8Mal>
  http://metadb.riken.jp/0001790IC57BL6Lattm8MalLattm8MalLattm8Mal
• decreased interleukin-2 secretion_Cd28<tm1Mak>/Cd28<tm1Mak>
  http://metadb.riken.jp/0008688I129S2SvPasCd28tm1MakCd28tm1MakCd28tm1Mak
• decreased T cell proliferation_Carmil2<bas>/Carmil2<bas>
  http://metadb.riken.jp/0005095IC3HeBFeJC57BL6Carmil2basCarmil2basCarmil2bas
• abnormal B cell number_Lat<tm8Mal>/Lat<tm8Mal>
  http://metadb.riken.jp/0002458IC57BL6Lattm8MalLattm8MalLattm8Mal
• decreased regulatory T cell number_Carmil2<bas>/Carmil2<tm1a(KOMP)Mbp>
  http://metadb.riken.jp/0004974IC3HeBFeJC57BL6C57BL6NCarmil2basCarmil2tm1aKOMPMbpCarmil2tm1aKOMPMbpCarmil2bas
• decreased T cell proliferation_Cd28<tm1Mak>/Cd28<tm1Mak>
  http://metadb.riken.jp/0005095I129S2SvPasCd28tm1MakCd28tm1MakCd28tm1Mak
• decreased interferon-gamma secretion_Carmil2<bas>/Carmil2<bas>
  http://metadb.riken.jp/0008567IC3HeBFeJC57BL6Carmil2basCarmil2basCarmil2bas
• decreased regulatory T cell number_Cd28<tm1Mak>/Cd28<tm1Mak>
  http://metadb.riken.jp/0004974I129S2SvPasCd28tm1MakCd28tm1MakCd28tm1Mak
• decreased interleukin-2 secretion_Carmil2<bas>/Carmil2<tm1a(KOMP)Mbp>
  http://metadb.riken.jp/0008688IC3HeBFeJC57BL6C57BL6NCarmil2basCarmil2tm1aKOMPMbpCarmil2tm1aKOMPMbpCarmil2bas

class

http://purl.org/net/cito/citesAsAuthority

• Carmil2<bas>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5547539
• Lat<tm8Mal>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5547536