Aae. Suzuki, et.al., RhoA is essential for maintaining normal megakaryocyte ploidy and platelet generation., PloS one, 2013, 8

http://rdf.ncbi.nlm.nih.gov/pubmed/23935982

Aae. Suzuki, et.al., RhoA is essential for maintaining normal megakaryocyte ploidy and platelet generation., PloS one, 2013, 8

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Rhoa<tm1Csab>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5548162

class

http://purl.org/net/cito/citesAsAuthority

• Rhoa<tm1Csab>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5548162

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal megakaryocyte morphology_Itga2b<tm1(GFP/cre)Emam>/Itga2b<tm1(GFP/cre)Emam>,Rhoa<tm1Csab>/Rhoa<tm1Csab>,Tg(ITGA2B)3Mako/0,Tg(Pf4-icre)Q3Rsko/0
  http://metadb.riken.jp/0002417I129S6SvEvTacC57BL6Itga2btm1GFPcreEmamItga2btm1GFPcreEmamRhoatm1CsabRhoatm1CsabTgITGA2B3Mako0TgPf4icreQ3Rsko0TgITGA2B3MakoRhoatm1CsabItga2btm1GFPcreEmamTgPf4icreQ3Rsko
• abnormal megakaryocyte differentiation_Itga2b<tm1(GFP/cre)Emam>/Itga2b<tm1(GFP/cre)Emam>,Rhoa<tm1Csab>/Rhoa<tm1Csab>,Tg(ITGA2B)3Mako/0,Tg(Pf4-icre)Q3Rsko/0
  http://metadb.riken.jp/0000229I129S6SvEvTacC57BL6Itga2btm1GFPcreEmamItga2btm1GFPcreEmamRhoatm1CsabRhoatm1CsabTgITGA2B3Mako0TgPf4icreQ3Rsko0TgITGA2B3MakoRhoatm1CsabItga2btm1GFPcreEmamTgPf4icreQ3Rsko
• thrombocytopenia_Rhoa<tm1Csab>/Rhoa<tm1Csab>,Tg(Pf4-icre)Q3Rsko/0
  http://metadb.riken.jp/0003179IC57BL6Rhoatm1CsabRhoatm1CsabTgPf4icreQ3Rsko0TgPf4icreQ3RskoRhoatm1Csab
• decreased megakaryocyte cell number_Itga2b<tm1(GFP/cre)Emam>/Itga2b<tm1(GFP/cre)Emam>,Rhoa<tm1Csab>/Rhoa<tm1Csab>,Tg(ITGA2B)3Mako/0,Tg(Pf4-icre)Q3Rsko/0
  http://metadb.riken.jp/0008255I129S6SvEvTacC57BL6Itga2btm1GFPcreEmamItga2btm1GFPcreEmamRhoatm1CsabRhoatm1CsabTgITGA2B3Mako0TgPf4icreQ3Rsko0TgITGA2B3MakoRhoatm1CsabItga2btm1GFPcreEmamTgPf4icreQ3Rsko
• no abnormal phenotype detected_Rhoa<tm1Csab>/Rhoa<tm1Csab>
  http://metadb.riken.jp/0002169NSRhoatm1CsabRhoatm1CsabRhoatm1Csab
• increased mean platelet volume_Rhoa<tm1Csab>/Rhoa<tm1Csab>,Tg(Pf4-icre)Q3Rsko/0
  http://metadb.riken.jp/0002599IC57BL6Rhoatm1CsabRhoatm1CsabTgPf4icreQ3Rsko0TgPf4icreQ3RskoRhoatm1Csab