Neeraj. Jain, et.al., Conditional N-WASP knockout in mouse brain implicates actin cytoskeleton regulation in hydrocephalus pathology., Experimental neurology, 2014, 254

http://rdf.ncbi.nlm.nih.gov/pubmed/24462670

Neeraj. Jain, et.al., Conditional N-WASP knockout in mouse brain implicates actin cytoskeleton regulation in hydrocephalus pathology., Experimental neurology, 2014, 254

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Wasl<tm1.1Ttha>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5620949

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal spine curvature_Wasl<tm1.1Ttha>/Wasl<tm1.1Ttha>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0004174IC57BL6SJLWasltm11TthaWasltm11TthaTgNescre1Kag0Wasltm11TthaTgNescre1Kag
• domed cranium_Wasl<tm1.1Ttha>/Wasl<tm1.1Ttha>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0000440IC57BL6SJLWasltm11TthaWasltm11TthaTgNescre1Kag0Wasltm11TthaTgNescre1Kag
• abnormal gait_Wasl<tm1.1Ttha>/Wasl<tm1.1Ttha>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0001406IC57BL6SJLWasltm11TthaWasltm11TthaTgNescre1Kag0Wasltm11TthaTgNescre1Kag
• increased brain size_Wasl<tm1.1Ttha>/Wasl<tm1.1Ttha>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0005238IC57BL6SJLWasltm11TthaWasltm11TthaTgNescre1Kag0Wasltm11TthaTgNescre1Kag
• abnormal septum of telencephalon morphology_Wasl<tm1.1Ttha>/Wasl<tm1.1Ttha>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0012003IC57BL6SJLWasltm11TthaWasltm11TthaTgNescre1Kag0Wasltm11TthaTgNescre1Kag
• abnormal brain vasculature morphology_Wasl<tm1.1Ttha>/Wasl<tm1.1Ttha>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0004950IC57BL6SJLWasltm11TthaWasltm11TthaTgNescre1Kag0Wasltm11TthaTgNescre1Kag
• abnormal postnatal subventricular zone morphology_Wasl<tm1.1Ttha>/Wasl<tm1.1Ttha>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0004275IC57BL6SJLWasltm11TthaWasltm11TthaTgNescre1Kag0Wasltm11TthaTgNescre1Kag
• obstructive hydrocephaly_Wasl<tm1.1Ttha>/Wasl<tm1.1Ttha>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0000917IC57BL6SJLWasltm11TthaWasltm11TthaTgNescre1Kag0Wasltm11TthaTgNescre1Kag
• no abnormal phenotype detected_Wasl<tm1.1Ttha>/Wasl<+>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0002169IC57BL6SJLWasltm11TthaWaslTgNescre1Kag0WaslTgNescre1KagWasltm11Ttha
• postnatal lethality, complete penetrance_Wasl<tm1.1Ttha>/Wasl<tm1.1Ttha>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0011085IC57BL6SJLWasltm11TthaWasltm11TthaTgNescre1Kag0Wasltm11TthaTgNescre1Kag
• hydroencephaly_Wasl<tm1.1Ttha>/Wasl<tm1.1Ttha>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0001891IC57BL6SJLWasltm11TthaWasltm11TthaTgNescre1Kag0Wasltm11TthaTgNescre1Kag
• enlarged brain ventricles_Wasl<tm1.1Ttha>/Wasl<tm1.1Ttha>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0011380IC57BL6SJLWasltm11TthaWasltm11TthaTgNescre1Kag0Wasltm11TthaTgNescre1Kag
• kyphosis_Wasl<tm1.1Ttha>/Wasl<tm1.1Ttha>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0000160IC57BL6SJLWasltm11TthaWasltm11TthaTgNescre1Kag0Wasltm11TthaTgNescre1Kag
• absent hippocampus_Wasl<tm1.1Ttha>/Wasl<tm1.1Ttha>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0000809IC57BL6SJLWasltm11TthaWasltm11TthaTgNescre1Kag0Wasltm11TthaTgNescre1Kag
• absent brain ependyma motile cilia_Wasl<tm1.1Ttha>/Wasl<tm1.1Ttha>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0011057IC57BL6SJLWasltm11TthaWasltm11TthaTgNescre1Kag0Wasltm11TthaTgNescre1Kag
• decreased body weight_Wasl<tm1.1Ttha>/Wasl<tm1.1Ttha>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0001262IC57BL6SJLWasltm11TthaWasltm11TthaTgNescre1Kag0Wasltm11TthaTgNescre1Kag
• dilated fourth ventricle_Wasl<tm1.1Ttha>/Wasl<tm1.1Ttha>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0000829IC57BL6SJLWasltm11TthaWasltm11TthaTgNescre1Kag0Wasltm11TthaTgNescre1Kag
• abnormal brain ependyma morphology_Wasl<tm1.1Ttha>/Wasl<tm1.1Ttha>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0010152IC57BL6SJLWasltm11TthaWasltm11TthaTgNescre1Kag0Wasltm11TthaTgNescre1Kag
• thin cerebral cortex_Wasl<tm1.1Ttha>/Wasl<tm1.1Ttha>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0006254IC57BL6SJLWasltm11TthaWasltm11TthaTgNescre1Kag0Wasltm11TthaTgNescre1Kag
• abnormal dorsal striatum morphology_Wasl<tm1.1Ttha>/Wasl<tm1.1Ttha>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0004102IC57BL6SJLWasltm11TthaWasltm11TthaTgNescre1Kag0Wasltm11TthaTgNescre1Kag
• postnatal growth retardation_Wasl<tm1.1Ttha>/Wasl<tm1.1Ttha>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0001732IC57BL6SJLWasltm11TthaWasltm11TthaTgNescre1Kag0Wasltm11TthaTgNescre1Kag
• decreased body size_Wasl<tm1.1Ttha>/Wasl<tm1.1Ttha>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0001265IC57BL6SJLWasltm11TthaWasltm11TthaTgNescre1Kag0Wasltm11TthaTgNescre1Kag
• dilated lateral ventricles_Wasl<tm1.1Ttha>/Wasl<tm1.1Ttha>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0000825IC57BL6SJLWasltm11TthaWasltm11TthaTgNescre1Kag0Wasltm11TthaTgNescre1Kag
• cerebral aqueductal stenosis_Wasl<tm1.1Ttha>/Wasl<tm1.1Ttha>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0002958IC57BL6SJLWasltm11TthaWasltm11TthaTgNescre1Kag0Wasltm11TthaTgNescre1Kag
• abnormal cerebral aqueduct morphology_Wasl<tm1.1Ttha>/Wasl<tm1.1Ttha>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0005537IC57BL6SJLWasltm11TthaWasltm11TthaTgNescre1Kag0Wasltm11TthaTgNescre1Kag
• enlarged cranium_Wasl<tm1.1Ttha>/Wasl<tm1.1Ttha>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0000439IC57BL6SJLWasltm11TthaWasltm11TthaTgNescre1Kag0Wasltm11TthaTgNescre1Kag
• lethargy_Wasl<tm1.1Ttha>/Wasl<tm1.1Ttha>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0005202IC57BL6SJLWasltm11TthaWasltm11TthaTgNescre1Kag0Wasltm11TthaTgNescre1Kag
• abnormal choroid plexus morphology_Wasl<tm1.1Ttha>/Wasl<tm1.1Ttha>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0000820IC57BL6SJLWasltm11TthaWasltm11TthaTgNescre1Kag0Wasltm11TthaTgNescre1Kag
• decreased corpus callosum size_Wasl<tm1.1Ttha>/Wasl<tm1.1Ttha>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0000781IC57BL6SJLWasltm11TthaWasltm11TthaTgNescre1Kag0Wasltm11TthaTgNescre1Kag
• astrocytosis_Wasl<tm1.1Ttha>/Wasl<tm1.1Ttha>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0003354IC57BL6SJLWasltm11TthaWasltm11TthaTgNescre1Kag0Wasltm11TthaTgNescre1Kag
• abnormal cerebral cortex morphology_Wasl<tm1.1Ttha>/Wasl<tm1.1Ttha>,Tg(Nes-cre)1Kag/0
  http://metadb.riken.jp/0000788IC57BL6SJLWasltm11TthaWasltm11TthaTgNescre1Kag0Wasltm11TthaTgNescre1Kag

class

http://purl.org/net/cito/citesAsAuthority

• Wasl<tm1.1Ttha>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5620949