Matthew J. Cecchini, et.al., A retinoblastoma allele that is mutated at its common E2F interaction site inhibits cell proliferation in gene-targeted mice., Molecular and cellular biology, 2014, 34

http://rdf.ncbi.nlm.nih.gov/pubmed/24662053

Matthew J. Cecchini, et.al., A retinoblastoma allele that is mutated at its common E2F interaction site inhibits cell proliferation in gene-targeted mice., Molecular and cellular biology, 2014, 34

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Rb1<tm2.1Fad>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5614046

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal enterocyte proliferation_Rb1<tm2Brn>/Rb1<tm2Brn>,Tg(Cyp1a1-cre)1Dwi/0
  http://metadb.riken.jp/0008883I129C57BL6CBARb1tm2BrnRb1tm2BrnTgCyp1a1cre1Dwi0TgCyp1a1cre1DwiRb1tm2Brn
• skeletal muscle atrophy_Rb1<tm2.1Fad>/Rb1<tm2.1Fad>
  http://metadb.riken.jp/0009417I129C57BL6Rb1tm21FadRb1tm21FadRb1tm21Fad
• postnatal lethality, incomplete penetrance_E2f1<tm1Meg>/E2f1<tm1Meg>,Rb1<tm2.1Fad>/Rb1<tm2.1Fad>
  http://metadb.riken.jp/0011086I129S4SvJaeC57BL6E2f1tm1MegE2f1tm1MegRb1tm21FadRb1tm21FadRb1tm21FadE2f1tm1Meg
• mammary gland duct hyperplasia_Rb1<tm2.1Fad>/Rb1<tm2.1Fad>
  http://metadb.riken.jp/0001885I129C57BL6Rb1tm21FadRb1tm21FadRb1tm21Fad
• respiratory distress_Rb1<tm2.1Fad>/Rb1<tm2.1Fad>
  http://metadb.riken.jp/0001954I129C57BL6Rb1tm21FadRb1tm21FadRb1tm21Fad
• neonatal lethality, incomplete penetrance_Rb1<tm2.1Fad>/Rb1<tm2.1Fad>
  http://metadb.riken.jp/0011088I129C57BL6Rb1tm21FadRb1tm21FadRb1tm21Fad
• postnatal lethality, incomplete penetrance_Rb1<tm1Tyj>/Rb1<+>
  http://metadb.riken.jp/0011086I129S2SvPasRb1tm1TyjRb1Rb1tm1TyjRb1
• increased pituitary gland tumor incidence_Rb1<tm1Tyj>/Rb1<+>
  http://metadb.riken.jp/0010320I129S2SvPasRb1tm1TyjRb1Rb1tm1TyjRb1

class

http://purl.org/net/cito/citesAsAuthority

• Rb1<tm2.1Fad>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5614046