Stephen. Lyle, et.al., Dicer cooperates with p53 to suppress DNA damage and skin carcinogenesis in mice., PloS one, 2014, 9

http://rdf.ncbi.nlm.nih.gov/pubmed/24979267

Stephen. Lyle, et.al., Dicer cooperates with p53 to suppress DNA damage and skin carcinogenesis in mice., PloS one, 2014, 9

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal hair follicle morphology_Dicer1<tm1Snj>/Dicer1<tm1Snj>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(KRT5-cre/PGR)1Der/0
  http://metadb.riken.jp/0000377I129P2OlaHsd129S7SvEvBrdC57BL6NFVBNICRDicer1tm1SnjDicer1tm1SnjTrp53tm1BrnTrp53tm1BrnTgKRT5crePGR1Der0TgKRT5crePGR1DerTrp53tm1BrnDicer1tm1Snj
• abnormal hair follicle morphology_Dicer1<tm1Snj>/Dicer1<tm1Snj>,Tg(KRT5-cre/PGR)1Der/0
  http://metadb.riken.jp/0000377I129S7SvEvBrdC57BL6FVBICRDicer1tm1SnjDicer1tm1SnjTgKRT5crePGR1Der0TgKRT5crePGR1DerDicer1tm1Snj
• decreased hair follicle number_Dicer1<tm1Snj>/Dicer1<tm1Snj>,Tg(KRT5-cre/PGR)1Der/0
  http://metadb.riken.jp/0000379I129S7SvEvBrdC57BL6FVBICRDicer1tm1SnjDicer1tm1SnjTgKRT5crePGR1Der0TgKRT5crePGR1DerDicer1tm1Snj
• abnormal hair cycle_Dicer1<tm1Snj>/Dicer1<tm1Snj>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(KRT5-cre/PGR)1Der/0
  http://metadb.riken.jp/0000427I129P2OlaHsd129S7SvEvBrdC57BL6NFVBNICRDicer1tm1SnjDicer1tm1SnjTrp53tm1BrnTrp53tm1BrnTgKRT5crePGR1Der0TgKRT5crePGR1DerTrp53tm1BrnDicer1tm1Snj
• abnormal epidermal layer morphology_Dicer1<tm1Snj>/Dicer1<tm1Snj>,Tg(KRT5-cre/PGR)1Der/0
  http://metadb.riken.jp/0001216I129S7SvEvBrdC57BL6FVBICRDicer1tm1SnjDicer1tm1SnjTgKRT5crePGR1Der0TgKRT5crePGR1DerDicer1tm1Snj
• thick epidermis_Dicer1<tm1Snj>/Dicer1<tm1Snj>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(KRT5-cre/PGR)1Der/0
  http://metadb.riken.jp/0001219I129P2OlaHsd129S7SvEvBrdC57BL6NFVBNICRDicer1tm1SnjDicer1tm1SnjTrp53tm1BrnTrp53tm1BrnTgKRT5crePGR1Der0TgKRT5crePGR1DerTrp53tm1BrnDicer1tm1Snj
他20件を見る
• thick epidermis_Dicer1<tm1Snj>/Dicer1<tm1Snj>,Tg(KRT5-cre/PGR)1Der/0
  http://metadb.riken.jp/0001219I129S7SvEvBrdC57BL6FVBICRDicer1tm1SnjDicer1tm1SnjTgKRT5crePGR1Der0TgKRT5crePGR1DerDicer1tm1Snj
• abnormal epidermis stratum basale morphology_Dicer1<tm1Snj>/Dicer1<tm1Snj>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(KRT5-cre/PGR)1Der/0
  http://metadb.riken.jp/0001231I129P2OlaHsd129S7SvEvBrdC57BL6NFVBNICRDicer1tm1SnjDicer1tm1SnjTrp53tm1BrnTrp53tm1BrnTgKRT5crePGR1Der0TgKRT5crePGR1DerTrp53tm1BrnDicer1tm1Snj
• loss of vibrissae_Dicer1<tm1Snj>/Dicer1<tm1Snj>,Tg(KRT5-cre/PGR)1Der/0
  http://metadb.riken.jp/0001280I129S7SvEvBrdC57BL6FVBICRDicer1tm1SnjDicer1tm1SnjTgKRT5crePGR1Der0TgKRT5crePGR1DerDicer1tm1Snj
• premature death_Dicer1<tm1Snj>/Dicer1<tm1Snj>,Trp53<tm1Brn>/Trp53<+>,Tg(KRT5-cre/PGR)1Der/0
  http://metadb.riken.jp/0002083I129P2OlaHsd129S7SvEvBrdC57BL6NFVBNICRDicer1tm1SnjDicer1tm1SnjTrp53tm1BrnTrp53TgKRT5crePGR1Der0Trp53Dicer1tm1SnjTgKRT5crePGR1DerTrp53tm1Brn
• premature death_Dicer1<tm1Snj>/Dicer1<tm1Snj>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(KRT5-cre/PGR)1Der/0
  http://metadb.riken.jp/0002083I129P2OlaHsd129S7SvEvBrdC57BL6NFVBNICRDicer1tm1SnjDicer1tm1SnjTrp53tm1BrnTrp53tm1BrnTgKRT5crePGR1Der0TgKRT5crePGR1DerTrp53tm1BrnDicer1tm1Snj
• premature death_Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(KRT5-cre/PGR)1Der/0
  http://metadb.riken.jp/0002083I129P2OlaHsdC57BL6NFVBNICRTrp53tm1BrnTrp53tm1BrnTgKRT5crePGR1Der0Trp53tm1BrnTgKRT5crePGR1Der
• premature death_Dicer1<tm1Snj>/Dicer1<tm1Snj>,Tg(KRT5-cre/PGR)1Der/0
  http://metadb.riken.jp/0002083I129S7SvEvBrdC57BL6FVBICRDicer1tm1SnjDicer1tm1SnjTgKRT5crePGR1Der0TgKRT5crePGR1DerDicer1tm1Snj
• hair follicle degeneration_Dicer1<tm1Snj>/Dicer1<tm1Snj>,Tg(KRT5-cre/PGR)1Der/0
  http://metadb.riken.jp/0003413I129S7SvEvBrdC57BL6FVBICRDicer1tm1SnjDicer1tm1SnjTgKRT5crePGR1Der0TgKRT5crePGR1DerDicer1tm1Snj
• abnormal hair shaft morphology_Dicer1<tm1Snj>/Dicer1<tm1Snj>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(KRT5-cre/PGR)1Der/0
  http://metadb.riken.jp/0003809I129P2OlaHsd129S7SvEvBrdC57BL6NFVBNICRDicer1tm1SnjDicer1tm1SnjTrp53tm1BrnTrp53tm1BrnTgKRT5crePGR1Der0TgKRT5crePGR1DerTrp53tm1BrnDicer1tm1Snj
• increased basal cell carcinoma incidence_Dicer1<tm1Snj>/Dicer1<tm1Snj>,Trp53<tm1Brn>/Trp53<+>,Tg(KRT5-cre/PGR)1Der/0
  http://metadb.riken.jp/0004208I129P2OlaHsd129S7SvEvBrdC57BL6NFVBNICRDicer1tm1SnjDicer1tm1SnjTrp53tm1BrnTrp53TgKRT5crePGR1Der0Trp53Dicer1tm1SnjTgKRT5crePGR1DerTrp53tm1Brn
• cachexia_Dicer1<tm1Snj>/Dicer1<tm1Snj>,Tg(KRT5-cre/PGR)1Der/0
  http://metadb.riken.jp/0005150I129S7SvEvBrdC57BL6FVBICRDicer1tm1SnjDicer1tm1SnjTgKRT5crePGR1Der0TgKRT5crePGR1DerDicer1tm1Snj
• abnormal skin physiology_Dicer1<tm1Snj>/Dicer1<tm1Snj>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(KRT5-cre/PGR)1Der/0
  http://metadb.riken.jp/0005501I129P2OlaHsd129S7SvEvBrdC57BL6NFVBNICRDicer1tm1SnjDicer1tm1SnjTrp53tm1BrnTrp53tm1BrnTgKRT5crePGR1Der0TgKRT5crePGR1DerTrp53tm1BrnDicer1tm1Snj
• abnormal skin physiology_Dicer1<tm1Snj>/Dicer1<tm1Snj>,Tg(KRT5-cre/PGR)1Der/0
  http://metadb.riken.jp/0005501I129S7SvEvBrdC57BL6FVBICRDicer1tm1SnjDicer1tm1SnjTgKRT5crePGR1Der0TgKRT5crePGR1DerDicer1tm1Snj
• progressive hair loss_Dicer1<tm1Snj>/Dicer1<tm1Snj>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(KRT5-cre/PGR)1Der/0
  http://metadb.riken.jp/0009004I129P2OlaHsd129S7SvEvBrdC57BL6NFVBNICRDicer1tm1SnjDicer1tm1SnjTrp53tm1BrnTrp53tm1BrnTgKRT5crePGR1Der0TgKRT5crePGR1DerTrp53tm1BrnDicer1tm1Snj
• progressive hair loss_Dicer1<tm1Snj>/Dicer1<tm1Snj>,Tg(KRT5-cre/PGR)1Der/0
  http://metadb.riken.jp/0009004I129S7SvEvBrdC57BL6FVBICRDicer1tm1SnjDicer1tm1SnjTgKRT5crePGR1Der0TgKRT5crePGR1DerDicer1tm1Snj
• hypergranulosis_Dicer1<tm1Snj>/Dicer1<tm1Snj>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(KRT5-cre/PGR)1Der/0
  http://metadb.riken.jp/0009600I129P2OlaHsd129S7SvEvBrdC57BL6NFVBNICRDicer1tm1SnjDicer1tm1SnjTrp53tm1BrnTrp53tm1BrnTgKRT5crePGR1Der0TgKRT5crePGR1DerTrp53tm1BrnDicer1tm1Snj
• increased skin squamous cell carcinoma incidence_Dicer1<tm1Snj>/Dicer1<tm1Snj>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(KRT5-cre/PGR)1Der/0
  http://metadb.riken.jp/0009704I129P2OlaHsd129S7SvEvBrdC57BL6NFVBNICRDicer1tm1SnjDicer1tm1SnjTrp53tm1BrnTrp53tm1BrnTgKRT5crePGR1Der0TgKRT5crePGR1DerTrp53tm1BrnDicer1tm1Snj
• increased skin squamous cell carcinoma incidence_Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(KRT5-cre/PGR)1Der/0
  http://metadb.riken.jp/0009704I129P2OlaHsdC57BL6NFVBNICRTrp53tm1BrnTrp53tm1BrnTgKRT5crePGR1Der0Trp53tm1BrnTgKRT5crePGR1Der
• increased skin tumor incidence_Dicer1<tm1Snj>/Dicer1<tm1Snj>,Trp53<tm1Brn>/Trp53<+>,Tg(KRT5-cre/PGR)1Der/0
  http://metadb.riken.jp/0010300I129P2OlaHsd129S7SvEvBrdC57BL6NFVBNICRDicer1tm1SnjDicer1tm1SnjTrp53tm1BrnTrp53TgKRT5crePGR1Der0Trp53Dicer1tm1SnjTgKRT5crePGR1DerTrp53tm1Brn
• increased skin tumor incidence_Dicer1<tm1Snj>/Dicer1<tm1Snj>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(KRT5-cre/PGR)1Der/0
  http://metadb.riken.jp/0010300I129P2OlaHsd129S7SvEvBrdC57BL6NFVBNICRDicer1tm1SnjDicer1tm1SnjTrp53tm1BrnTrp53tm1BrnTgKRT5crePGR1Der0TgKRT5crePGR1DerTrp53tm1BrnDicer1tm1Snj