Takashi. Yamaguchi, et.al., A genetically engineered mouse model developing rapid progressive pancreatic ductal adenocarcinoma., The Journal of pathology, 2014, 234

http://rdf.ncbi.nlm.nih.gov/pubmed/25042889

Takashi. Yamaguchi, et.al., A genetically engineered mouse model developing rapid progressive pancreatic ductal adenocarcinoma., The Journal of pathology, 2014, 234

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal pancreatic duct morphology_Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0009143I129S4SvJaeC57BL6FVBNKrastm4TyjKrasTgPdx1cre6Tuv0TgPdx1cre6TuvKrastm4TyjKras
• increased pancreatic intraepithelial neoplasia incidence_Kras<tm4Tyj>/Kras<+>,Tg(CAG-Bgeo,-tsA58T)T26Ichi/0,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0009152I129P2OlaHsd129S4SvJaeC57BL6FVBNKrastm4TyjKrasTgCAGBgeotsA58TT26Ichi0TgPdx1cre6Tuv0TgPdx1cre6TuvKrastm4TyjKrasTgCAGBgeotsA58TT26Ichi
• hemorrhagic ascites_Kras<tm4Tyj>/Kras<+>,Tg(CAG-Bgeo,-tsA58T)T26Ichi/0,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0013184I129P2OlaHsd129S4SvJaeC57BL6FVBNKrastm4TyjKrasTgCAGBgeotsA58TT26Ichi0TgPdx1cre6Tuv0TgPdx1cre6TuvKrastm4TyjKrasTgCAGBgeotsA58TT26Ichi
• increased pancreatic intraepithelial neoplasia incidence_Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0009152I129S4SvJaeC57BL6FVBNKrastm4TyjKrasTgPdx1cre6Tuv0TgPdx1cre6TuvKrastm4TyjKras
• increased pancreatic ductal adenocarcinoma incidence_Kras<tm4Tyj>/Kras<+>,Tg(CAG-Bgeo,-tsA58T)T26Ichi/0,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0009151I129P2OlaHsd129S4SvJaeC57BL6FVBNKrastm4TyjKrasTgCAGBgeotsA58TT26Ichi0TgPdx1cre6Tuv0TgPdx1cre6TuvKrastm4TyjKrasTgCAGBgeotsA58TT26Ichi
• pancreatic acinar-to-ductal metaplasia_Kras<tm4Tyj>/Kras<+>,Tg(CAG-Bgeo,-tsA58T)T26Ichi/0,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0013221I129P2OlaHsd129S4SvJaeC57BL6FVBNKrastm4TyjKrasTgCAGBgeotsA58TT26Ichi0TgPdx1cre6Tuv0TgPdx1cre6TuvKrastm4TyjKrasTgCAGBgeotsA58TT26Ichi
• abnormal pancreatic acinar cell morphology_Tg(CAG-Bgeo,-tsA58T)T26Ichi/0,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0009146I129P2OlaHsdC57BL6FVBNTgCAGBgeotsA58TT26Ichi0TgPdx1cre6Tuv0TgCAGBgeotsA58TT26IchiTgPdx1cre6Tuv
• premature death_Tg(CAG-Bgeo,-tsA58T)T26Ichi/0,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0002083I129P2OlaHsdC57BL6FVBNTgCAGBgeotsA58TT26Ichi0TgPdx1cre6Tuv0TgCAGBgeotsA58TT26IchiTgPdx1cre6Tuv
• abnormal pancreatic duct morphology_Tg(CAG-Bgeo,-tsA58T)T26Ichi/0,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0009143I129P2OlaHsdC57BL6FVBNTgCAGBgeotsA58TT26Ichi0TgPdx1cre6Tuv0TgCAGBgeotsA58TT26IchiTgPdx1cre6Tuv
• postnatal lethality, complete penetrance_Kras<tm4Tyj>/Kras<+>,Tg(CAG-Bgeo,-tsA58T)T26Ichi/0,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0011085I129P2OlaHsd129S4SvJaeC57BL6FVBNKrastm4TyjKrasTgCAGBgeotsA58TT26Ichi0TgPdx1cre6Tuv0TgPdx1cre6TuvKrastm4TyjKrasTgCAGBgeotsA58TT26Ichi