Angela K. Odle, et.al., Adipocyte versus pituitary leptin in the regulation of pituitary hormones: somatotropes develop normally in the absence of circulating leptin., Endocrinology, 2014, 155

http://rdf.ncbi.nlm.nih.gov/pubmed/25116704

Angela K. Odle, et.al., Adipocyte versus pituitary leptin in the regulation of pituitary hormones: somatotropes develop normally in the absence of circulating leptin., Endocrinology, 2014, 155

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Lep<tm1.1Gvcao>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5707692
• Lep<tm1.2Gvcao>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5707695

class

http://purl.org/net/cito/citesAsAuthority

• Lep<tm1.1Gvcao>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5707692
• Lep<tm1.2Gvcao>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5707695

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• male infertility_Lep<tm1.2Gvcao>/Lep<tm1.2Gvcao>
  http://metadb.riken.jp/0001925I129S4SvJaeSorFVBNJFVBNTacLeptm12GvcaoLeptm12GvcaoLeptm12Gvcao
• increased body weight_Lep<tm1.2Gvcao>/Lep<tm1.2Gvcao>
  http://metadb.riken.jp/0001260I129S4SvJaeSorFVBNJFVBNTacLeptm12GvcaoLeptm12GvcaoLeptm12Gvcao
• decreased circulating follicle stimulating hormone level_Lep<tm1.2Gvcao>/Lep<tm1.2Gvcao>
  http://metadb.riken.jp/0002790I129S4SvJaeSorFVBNJFVBNTacLeptm12GvcaoLeptm12GvcaoLeptm12Gvcao
• decreased circulating prolactin level_Lep<tm1.1Gvcao>/Lep<tm1.1Gvcao>,Tg(Adipoq-cre)1Evdr/0
  http://metadb.riken.jp/0005121I129S4SvJaeSorC57BL6JFVBNTacLeptm11GvcaoLeptm11GvcaoTgAdipoqcre1Evdr0Leptm11GvcaoTgAdipoqcre1Evdr
• decreased circulating follicle stimulating hormone level_Lep<tm1.1Gvcao>/Lep<tm1.1Gvcao>,Tg(Adipoq-cre)1Evdr/0
  http://metadb.riken.jp/0002790I129S4SvJaeSorC57BL6JFVBNTacLeptm11GvcaoLeptm11GvcaoTgAdipoqcre1Evdr0Leptm11GvcaoTgAdipoqcre1Evdr
• increased pituitary hormone level_Lep<tm1.1Gvcao>/Lep<tm1.1Gvcao>,Tg(Adipoq-cre)1Evdr/0
  http://metadb.riken.jp/0003973I129S4SvJaeSorC57BL6JFVBNTacLeptm11GvcaoLeptm11GvcaoTgAdipoqcre1Evdr0Leptm11GvcaoTgAdipoqcre1Evdr
• infertility_Lep<tm1.1Gvcao>/Lep<tm1.1Gvcao>,Tg(Adipoq-cre)1Evdr/0
  http://metadb.riken.jp/0001924I129S4SvJaeSorC57BL6JFVBNTacLeptm11GvcaoLeptm11GvcaoTgAdipoqcre1Evdr0Leptm11GvcaoTgAdipoqcre1Evdr
• decreased pituitary hormone level_Lep<tm1.2Gvcao>/Lep<tm1.2Gvcao>
  http://metadb.riken.jp/0003972I129S4SvJaeSorFVBNJFVBNTacLeptm12GvcaoLeptm12GvcaoLeptm12Gvcao
• decreased circulating leptin level_Lep<tm1.1Gvcao>/Lep<tm1.1Gvcao>,Tg(Adipoq-cre)1Evdr/0
  http://metadb.riken.jp/0005668I129S4SvJaeSorC57BL6JFVBNTacLeptm11GvcaoLeptm11GvcaoTgAdipoqcre1Evdr0Leptm11GvcaoTgAdipoqcre1Evdr
• infertility_Lep<tm1.2Gvcao>/Lep<tm1.2Gvcao>
  http://metadb.riken.jp/0001924I129S4SvJaeSorFVBNJFVBNTacLeptm12GvcaoLeptm12GvcaoLeptm12Gvcao
• decreased somatotroph cell number_Lep<tm1.2Gvcao>/Lep<tm1.2Gvcao>
  http://metadb.riken.jp/0008329I129S4SvJaeSorFVBNJFVBNTacLeptm12GvcaoLeptm12GvcaoLeptm12Gvcao
• decreased circulating prolactin level_Lep<tm1.2Gvcao>/Lep<tm1.2Gvcao>
  http://metadb.riken.jp/0005121I129S4SvJaeSorFVBNJFVBNTacLeptm12GvcaoLeptm12GvcaoLeptm12Gvcao
• female infertility_Lep<tm1.2Gvcao>/Lep<tm1.2Gvcao>
  http://metadb.riken.jp/0001926I129S4SvJaeSorFVBNJFVBNTacLeptm12GvcaoLeptm12GvcaoLeptm12Gvcao
• female infertility_Lep<tm1.1Gvcao>/Lep<tm1.1Gvcao>,Tg(Adipoq-cre)1Evdr/0
  http://metadb.riken.jp/0001926I129S4SvJaeSorC57BL6JFVBNTacLeptm11GvcaoLeptm11GvcaoTgAdipoqcre1Evdr0Leptm11GvcaoTgAdipoqcre1Evdr
• male infertility_Lep<tm1.1Gvcao>/Lep<tm1.1Gvcao>,Tg(Adipoq-cre)1Evdr/0
  http://metadb.riken.jp/0001925I129S4SvJaeSorC57BL6JFVBNTacLeptm11GvcaoLeptm11GvcaoTgAdipoqcre1Evdr0Leptm11GvcaoTgAdipoqcre1Evdr
• decreased circulating growth hormone level_Lep<tm1.1Gvcao>/Lep<tm1.1Gvcao>,Tg(Adipoq-cre)1Evdr/0
  http://metadb.riken.jp/0005120I129S4SvJaeSorC57BL6JFVBNTacLeptm11GvcaoLeptm11GvcaoTgAdipoqcre1Evdr0Leptm11GvcaoTgAdipoqcre1Evdr
• obese_Lep<tm1.1Gvcao>/Lep<tm1.1Gvcao>,Tg(Adipoq-cre)1Evdr/0
  http://metadb.riken.jp/0001261I129S4SvJaeSorC57BL6JFVBNTacLeptm11GvcaoLeptm11GvcaoTgAdipoqcre1Evdr0Leptm11GvcaoTgAdipoqcre1Evdr
• decreased circulating leptin level_Lep<tm1.2Gvcao>/Lep<tm1.2Gvcao>
  http://metadb.riken.jp/0005668I129S4SvJaeSorFVBNJFVBNTacLeptm12GvcaoLeptm12GvcaoLeptm12Gvcao
• obese_Lep<tm1.2Gvcao>/Lep<tm1.2Gvcao>
  http://metadb.riken.jp/0001261I129S4SvJaeSorFVBNJFVBNTacLeptm12GvcaoLeptm12GvcaoLeptm12Gvcao
• decreased circulating luteinizing hormone level_Lep<tm1.1Gvcao>/Lep<tm1.1Gvcao>,Tg(Adipoq-cre)1Evdr/0
  http://metadb.riken.jp/0002773I129S4SvJaeSorC57BL6JFVBNTacLeptm11GvcaoLeptm11GvcaoTgAdipoqcre1Evdr0Leptm11GvcaoTgAdipoqcre1Evdr