Jeff C. Liu, et.al., Combined deletion of Pten and p53 in mammary epithelium accelerates triple-negative breast cancer with dependency on eEF2K., EMBO molecular medicine, 2014, 6

http://rdf.ncbi.nlm.nih.gov/pubmed/25330770

Jeff C. Liu, et.al., Combined deletion of Pten and p53 in mammary epithelium accelerates triple-negative breast cancer with dependency on eEF2K., EMBO molecular medicine, 2014, 6

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased mammary gland tumor incidence_Pten<tm2Mak>/Pten<tm2Mak>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Wap-cre)11738Mam/0
  http://metadb.riken.jp/0010299I129P2OlaHsdC57BL6FVBNSJLPtentm2MakPtentm2MakTrp53tm1BrnTrp53tm1BrnTgWapcre11738Mam0TgWapcre11738MamTrp53tm1BrnPtentm2Mak
• increased spindle cell carcinoma incidence_Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(MMTV-cre)#Tfln/0
  http://metadb.riken.jp/0010367I129P2OlaHsdC57BL6FVBNTrp53tm1BrnTrp53tm1BrnTgMMTVcreTfln0TgMMTVcreTflnTrp53tm1Brn
• increased mammary gland tumor incidence_Pten<tm2Mak>/Pten<tm2Mak>,Tg(Wap-cre)11738Mam/0
  http://metadb.riken.jp/0010299I129P2OlaHsdC57BL6FVBNSJLPtentm2MakPtentm2MakTgWapcre11738Mam0Ptentm2MakTgWapcre11738Mam
• increased mammary adenocarcinoma incidence_Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(MMTV-cre)#Tfln/0
  http://metadb.riken.jp/0001883I129P2OlaHsdC57BL6FVBNTrp53tm1BrnTrp53tm1BrnTgMMTVcreTfln0TgMMTVcreTflnTrp53tm1Brn
• increased mammary gland tumor incidence in breeding females_Pten<tm2Mak>/Pten<tm2Mak>,Tg(MMTV-cre)#Tfln/0
  http://metadb.riken.jp/0012570I129P2OlaHsdC57BL6FVBNPtentm2MakPtentm2MakTgMMTVcreTfln0Ptentm2MakTgMMTVcreTfln
• increased mammary adenocarcinoma incidence_Pten<tm2Mak>/Pten<tm2Mak>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Wap-cre)11738Mam/0
  http://metadb.riken.jp/0001883I129P2OlaHsdC57BL6FVBNSJLPtentm2MakPtentm2MakTrp53tm1BrnTrp53tm1BrnTgWapcre11738Mam0TgWapcre11738MamTrp53tm1BrnPtentm2Mak
• increased mammary gland tumor incidence_Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(MMTV-cre)#Tfln/0
  http://metadb.riken.jp/0010299I129P2OlaHsdC57BL6FVBNTrp53tm1BrnTrp53tm1BrnTgMMTVcreTfln0TgMMTVcreTflnTrp53tm1Brn
• increased spindle cell carcinoma incidence_Pten<tm2Mak>/Pten<tm2Mak>,Tg(MMTV-cre)#Tfln/0
  http://metadb.riken.jp/0010367I129P2OlaHsdC57BL6FVBNPtentm2MakPtentm2MakTgMMTVcreTfln0Ptentm2MakTgMMTVcreTfln
• increased mammary adenocarcinoma incidence_Pten<tm2Mak>/Pten<tm2Mak>,Tg(Wap-cre)11738Mam/0
  http://metadb.riken.jp/0001883I129P2OlaHsdC57BL6FVBNSJLPtentm2MakPtentm2MakTgWapcre11738Mam0Ptentm2MakTgWapcre11738Mam
• increased mammary gland tumor incidence_Pten<tm2Mak>/Pten<tm2Mak>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(MMTV-cre)#Tfln/0
  http://metadb.riken.jp/0010299I129P2OlaHsdC57BL6FVBNPtentm2MakPtentm2MakTrp53tm1BrnTrp53tm1BrnTgMMTVcreTfln0Trp53tm1BrnPtentm2MakTgMMTVcreTfln
• increased mammary gland tumor incidence_Pten<tm2Mak>/Pten<tm2Mak>,Tg(MMTV-cre)#Tfln/0
  http://metadb.riken.jp/0010299I129P2OlaHsdC57BL6FVBNPtentm2MakPtentm2MakTgMMTVcreTfln0Ptentm2MakTgMMTVcreTfln
• increased mammary adenocarcinoma incidence_Pten<tm2Mak>/Pten<tm2Mak>,Tg(MMTV-cre)#Tfln/0
  http://metadb.riken.jp/0001883I129P2OlaHsdC57BL6FVBNPtentm2MakPtentm2MakTgMMTVcreTfln0Ptentm2MakTgMMTVcreTfln
• increased myoepithelioma incidence_Pten<tm2Mak>/Pten<tm2Mak>,Tg(Wap-cre)11738Mam/0
  http://metadb.riken.jp/0012043I129P2OlaHsdC57BL6FVBNSJLPtentm2MakPtentm2MakTgWapcre11738Mam0Ptentm2MakTgWapcre11738Mam
• increased mammary gland tumor incidence in breeding females_Pten<tm2Mak>/Pten<tm2Mak>,Tg(Wap-cre)11738Mam/0
  http://metadb.riken.jp/0012570I129P2OlaHsdC57BL6FVBNSJLPtentm2MakPtentm2MakTgWapcre11738Mam0Ptentm2MakTgWapcre11738Mam
• increased myoepithelioma incidence_Pten<tm2Mak>/Pten<tm2Mak>,Tg(MMTV-cre)#Tfln/0
  http://metadb.riken.jp/0012043I129P2OlaHsdC57BL6FVBNPtentm2MakPtentm2MakTgMMTVcreTfln0Ptentm2MakTgMMTVcreTfln
• increased spindle cell carcinoma incidence_Pten<tm2Mak>/Pten<tm2Mak>,Tg(Wap-cre)11738Mam/0
  http://metadb.riken.jp/0010367I129P2OlaHsdC57BL6FVBNSJLPtentm2MakPtentm2MakTgWapcre11738Mam0Ptentm2MakTgWapcre11738Mam
• increased spindle cell carcinoma incidence_Pten<tm2Mak>/Pten<tm2Mak>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(MMTV-cre)#Tfln/0
  http://metadb.riken.jp/0010367I129P2OlaHsdC57BL6FVBNPtentm2MakPtentm2MakTrp53tm1BrnTrp53tm1BrnTgMMTVcreTfln0Trp53tm1BrnPtentm2MakTgMMTVcreTfln
• increased myoepithelioma incidence_Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(MMTV-cre)#Tfln/0
  http://metadb.riken.jp/0012043I129P2OlaHsdC57BL6FVBNTrp53tm1BrnTrp53tm1BrnTgMMTVcreTfln0TgMMTVcreTflnTrp53tm1Brn
• increased myoepithelioma incidence_Pten<tm2Mak>/Pten<tm2Mak>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Wap-cre)11738Mam/0
  http://metadb.riken.jp/0012043I129P2OlaHsdC57BL6FVBNSJLPtentm2MakPtentm2MakTrp53tm1BrnTrp53tm1BrnTgWapcre11738Mam0TgWapcre11738MamTrp53tm1BrnPtentm2Mak
• increased myoepithelioma incidence_Pten<tm2Mak>/Pten<tm2Mak>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(MMTV-cre)#Tfln/0
  http://metadb.riken.jp/0012043I129P2OlaHsdC57BL6FVBNPtentm2MakPtentm2MakTrp53tm1BrnTrp53tm1BrnTgMMTVcreTfln0Trp53tm1BrnPtentm2MakTgMMTVcreTfln
• increased mammary adenocarcinoma incidence_Pten<tm2Mak>/Pten<tm2Mak>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(MMTV-cre)#Tfln/0
  http://metadb.riken.jp/0001883I129P2OlaHsdC57BL6FVBNPtentm2MakPtentm2MakTrp53tm1BrnTrp53tm1BrnTgMMTVcreTfln0Trp53tm1BrnPtentm2MakTgMMTVcreTfln
• increased spindle cell carcinoma incidence_Pten<tm2Mak>/Pten<tm2Mak>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Wap-cre)11738Mam/0
  http://metadb.riken.jp/0010367I129P2OlaHsdC57BL6FVBNSJLPtentm2MakPtentm2MakTrp53tm1BrnTrp53tm1BrnTgWapcre11738Mam0TgWapcre11738MamTrp53tm1BrnPtentm2Mak

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased mammary adenocarcinoma incidence in RBRC02301
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020392
• increased mammary gland tumor incidence in RBRC02301
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020391
• increased spindle cell carcinoma incidence in RBRC02301
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020394
• increased mammary gland tumor incidence in breeding females in RBRC02301
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020393
• increased myoepithelioma incidence in RBRC02301
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020395