Christopher. Jakobs, et.al., AIM2 Drives Joint Inflammation in a Self-DNA Triggered Model of Chronic Polyarthritis., PloS one, 2015, 10

http://rdf.ncbi.nlm.nih.gov/pubmed/26114879

Christopher. Jakobs, et.al., AIM2 Drives Joint Inflammation in a Self-DNA Triggered Model of Chronic Polyarthritis., PloS one, 2015, 10

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Aim2<tm1.1Arte>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5823429
• Aim2<tm1.2Arte>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5823433

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• enlarged spleen_Dnase2a<tm1Osa>/Dnase2a<tm1Osa>,Ifnar1<tm1Agt>/Ifnar1<tm1Agt>
  http://metadb.riken.jp/0000691I129S1Sv129S2SvPas129X1SvJC57BL6Dnase2atm1OsaDnase2atm1OsaIfnar1tm1AgtIfnar1tm1AgtIfnar1tm1AgtDnase2atm1Osa
• increased circulating interleukin-10 level_Aim2<tm1.2Arte>/Aim2<tm1.2Arte>,Dnase2a<tm1Osa>/Dnase2a<tm1Osa>,Ifnar1<tm1Agt>/Ifnar1<tm1Agt>
  http://metadb.riken.jp/0008593I129BALBcC57BL6C57BL6JAim2tm12ArteAim2tm12ArteDnase2atm1OsaDnase2atm1OsaIfnar1tm1AgtIfnar1tm1AgtAim2tm12ArteDnase2atm1OsaIfnar1tm1Agt
• increased circulating tumor necrosis factor level_Aim2<tm1.2Arte>/Aim2<tm1.2Arte>,Dnase2a<tm1Osa>/Dnase2a<tm1Osa>,Ifnar1<tm1Agt>/Ifnar1<tm1Agt>
  http://metadb.riken.jp/0008553I129BALBcC57BL6C57BL6JAim2tm12ArteAim2tm12ArteDnase2atm1OsaDnase2atm1OsaIfnar1tm1AgtIfnar1tm1AgtAim2tm12ArteDnase2atm1OsaIfnar1tm1Agt
• increased spleen weight_Dnase2a<tm1Osa>/Dnase2a<tm1Osa>,Ifnar1<tm1Agt>/Ifnar1<tm1Agt>
  http://metadb.riken.jp/0004952I129S1Sv129S2SvPas129X1SvJC57BL6Dnase2atm1OsaDnase2atm1OsaIfnar1tm1AgtIfnar1tm1AgtIfnar1tm1AgtDnase2atm1Osa
• increased circulating interleukin-10 level_Dnase2a<tm1Osa>/Dnase2a<tm1Osa>,Ifnar1<tm1Agt>/Ifnar1<tm1Agt>
  http://metadb.riken.jp/0008593I129S1Sv129S2SvPas129X1SvJC57BL6Dnase2atm1OsaDnase2atm1OsaIfnar1tm1AgtIfnar1tm1AgtIfnar1tm1AgtDnase2atm1Osa
• increased circulating tumor necrosis factor level_Dnase2a<tm1Osa>/Dnase2a<tm1Osa>,Ifnar1<tm1Agt>/Ifnar1<tm1Agt>
  http://metadb.riken.jp/0008553I129S1Sv129S2SvPas129X1SvJC57BL6Dnase2atm1OsaDnase2atm1OsaIfnar1tm1AgtIfnar1tm1AgtIfnar1tm1AgtDnase2atm1Osa
• increased autoantibody level_Aim2<tm1.2Arte>/Aim2<tm1.2Arte>,Dnase2a<tm1Osa>/Dnase2a<tm1Osa>,Ifnar1<tm1Agt>/Ifnar1<tm1Agt>
  http://metadb.riken.jp/0003725I129BALBcC57BL6C57BL6JAim2tm12ArteAim2tm12ArteDnase2atm1OsaDnase2atm1OsaIfnar1tm1AgtIfnar1tm1AgtAim2tm12ArteDnase2atm1OsaIfnar1tm1Agt
• abnormal spleen morphology_Aim2<tm1.2Arte>/Aim2<tm1.2Arte>,Dnase2a<tm1Osa>/Dnase2a<tm1Osa>,Ifnar1<tm1Agt>/Ifnar1<tm1Agt>
  http://metadb.riken.jp/0000689I129BALBcC57BL6C57BL6JAim2tm12ArteAim2tm12ArteDnase2atm1OsaDnase2atm1OsaIfnar1tm1AgtIfnar1tm1AgtAim2tm12ArteDnase2atm1OsaIfnar1tm1Agt
• joint inflammation_Dnase2a<tm1Osa>/Dnase2a<tm1Osa>,Ifnar1<tm1Agt>/Ifnar1<tm1Agt>
  http://metadb.riken.jp/0002933I129S1Sv129S2SvPas129X1SvJC57BL6Dnase2atm1OsaDnase2atm1OsaIfnar1tm1AgtIfnar1tm1AgtIfnar1tm1AgtDnase2atm1Osa
• rheumatoid arthritis_Dnase2a<tm1Osa>/Dnase2a<tm1Osa>,Ifnar1<tm1Agt>/Ifnar1<tm1Agt>
  http://metadb.riken.jp/0003561I129S1Sv129S2SvPas129X1SvJC57BL6Dnase2atm1OsaDnase2atm1OsaIfnar1tm1AgtIfnar1tm1AgtIfnar1tm1AgtDnase2atm1Osa
• increased autoantibody level_Dnase2a<tm1Osa>/Dnase2a<tm1Osa>,Ifnar1<tm1Agt>/Ifnar1<tm1Agt>
  http://metadb.riken.jp/0003725I129S1Sv129S2SvPas129X1SvJC57BL6Dnase2atm1OsaDnase2atm1OsaIfnar1tm1AgtIfnar1tm1AgtIfnar1tm1AgtDnase2atm1Osa
• enlarged spleen_Aim2<tm1.2Arte>/Aim2<tm1.2Arte>,Dnase2a<tm1Osa>/Dnase2a<tm1Osa>,Ifnar1<tm1Agt>/Ifnar1<tm1Agt>
  http://metadb.riken.jp/0000691I129BALBcC57BL6C57BL6JAim2tm12ArteAim2tm12ArteDnase2atm1OsaDnase2atm1OsaIfnar1tm1AgtIfnar1tm1AgtAim2tm12ArteDnase2atm1OsaIfnar1tm1Agt
• increased spleen weight_Aim2<tm1.2Arte>/Aim2<tm1.2Arte>,Dnase2a<tm1Osa>/Dnase2a<tm1Osa>,Ifnar1<tm1Agt>/Ifnar1<tm1Agt>
  http://metadb.riken.jp/0004952I129BALBcC57BL6C57BL6JAim2tm12ArteAim2tm12ArteDnase2atm1OsaDnase2atm1OsaIfnar1tm1AgtIfnar1tm1AgtAim2tm12ArteDnase2atm1OsaIfnar1tm1Agt
• rheumatoid arthritis_Aim2<tm1.2Arte>/Aim2<tm1.2Arte>,Dnase2a<tm1Osa>/Dnase2a<tm1Osa>,Ifnar1<tm1Agt>/Ifnar1<tm1Agt>
  http://metadb.riken.jp/0003561I129BALBcC57BL6C57BL6JAim2tm12ArteAim2tm12ArteDnase2atm1OsaDnase2atm1OsaIfnar1tm1AgtIfnar1tm1AgtAim2tm12ArteDnase2atm1OsaIfnar1tm1Agt
• abnormal spleen morphology_Dnase2a<tm1Osa>/Dnase2a<tm1Osa>,Ifnar1<tm1Agt>/Ifnar1<tm1Agt>
  http://metadb.riken.jp/0000689I129S1Sv129S2SvPas129X1SvJC57BL6Dnase2atm1OsaDnase2atm1OsaIfnar1tm1AgtIfnar1tm1AgtIfnar1tm1AgtDnase2atm1Osa

class

http://purl.org/net/cito/citesAsAuthority

• Aim2<tm1.1Arte>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5823429
• Aim2<tm1.2Arte>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5823433