increased circulating tumor necrosis factor level_Dnase2a<tm1Osa>/Dnase2a<tm1Osa>,Ifnar1<tm1Agt>/Ifnar1<tm1Agt>

http://metadb.riken.jp/0008553I129S1Sv129S2SvPas129X1SvJC57BL6Dnase2atm1OsaDnase2atm1OsaIfnar1tm1AgtIfnar1tm1AgtIfnar1tm1AgtDnase2atm1Osa

increased circulating tumor necrosis factor level_Dnase2a<tm1Osa>/Dnase2a<tm1Osa>,Ifnar1<tm1Agt>/Ifnar1<tm1Agt>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• interferon (alpha and beta) receptor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:107658
• deoxyribonuclease II alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:1329019

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Dnase2a<tm1Osa>/Dnase2a<tm1Osa>,Ifnar1<tm1Agt>/Ifnar1<tm1Agt>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ifnar1<tm1Agt>|Dnase2a<tm1Osa>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating tumor necrosis factor level
  http://purl.obolibrary.org/obo/MP_0008553

文献

http://purl.org/net/cito/citesAsAuthority

• Christopher. Jakobs, et.al., AIM2 Drives Joint Inflammation in a Self-DNA Triggered Model of Chronic Polyarthritis., PloS one, 2015, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/26114879
• Kohki. Kawane, et.al., Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages., Nature, 2006, 443
  http://rdf.ncbi.nlm.nih.gov/pubmed/17066036