Christophe. Lachaud, et.al., Karyomegalic interstitial nephritis and DNA damage-induced polyploidy in Fan1 nuclease-defective knock-in mice., Genes & development, 2016, 30

http://rdf.ncbi.nlm.nih.gov/pubmed/26980188

Christophe. Lachaud, et.al., Karyomegalic interstitial nephritis and DNA damage-induced polyploidy in Fan1 nuclease-defective knock-in mice., Genes & development, 2016, 30

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal renal tubule morphology_Fan1<tm1.1Jrou>/Fan1<tm1.1Jrou>
  http://metadb.riken.jp/0002703I129P2OlaHsdFan1tm11JrouFan1tm11JrouFan1tm11Jrou
• increased physiological sensitivity to xenobiotic_Fan1<tm1.1Jrou>/Fan1<tm1.1Jrou>,Slx4<tm1.2Jrou>/Slx4<tm1.2Jrou>
  http://metadb.riken.jp/0008873I129P2OlaHsdFan1tm11JrouFan1tm11JrouSlx4tm12JrouSlx4tm12JrouSlx4tm12JrouFan1tm11Jrou
• increased physiological sensitivity to xenobiotic_Fan1<tm1.1Jrou>/Fan1<tm1.1Jrou>
  http://metadb.riken.jp/0008873I129P2OlaHsdFan1tm11JrouFan1tm11JrouFan1tm11Jrou
• increased physiological sensitivity to xenobiotic_Fan1<tm1.1Jrou>/Fan1<tm1.1Jrou>,Slx1b<tm1.1Jrou>/Slx1b<tm1.1Jrou>
  http://metadb.riken.jp/0008873I129P2OlaHsdFan1tm11JrouFan1tm11JrouSlx1btm11JrouSlx1btm11JrouFan1tm11JrouSlx1btm11Jrou
• dilated renal tubules_Fan1<tm1.1Jrou>/Fan1<tm1.1Jrou>
  http://metadb.riken.jp/0002705I129P2OlaHsdFan1tm11JrouFan1tm11JrouFan1tm11Jrou
• increased physiological sensitivity to xenobiotic_Fan1<tm1.1Jrou>/Fan1<tm1.1Jrou>,Fancd2<Gt(OST57859)Lex>/Fancd2<Gt(OST57859)Lex>
  http://metadb.riken.jp/0008873I129P2OlaHsd129S5SvEvBrdFan1tm11JrouFan1tm11JrouFancd2GtOST57859LexFancd2GtOST57859LexFancd2GtOST57859LexFan1tm11Jrou
• polyploidy_Fan1<tm1.1Jrou>/Fan1<tm1.1Jrou>
  http://metadb.riken.jp/0004025I129P2OlaHsdFan1tm11JrouFan1tm11JrouFan1tm11Jrou
• renal tubule atrophy_Fan1<tm1.1Jrou>/Fan1<tm1.1Jrou>
  http://metadb.riken.jp/0011346I129P2OlaHsdFan1tm11JrouFan1tm11JrouFan1tm11Jrou
• abnormal renal tubule epithelium morphology_Fan1<tm1.1Jrou>/Fan1<tm1.1Jrou>
  http://metadb.riken.jp/0009640I129P2OlaHsdFan1tm11JrouFan1tm11JrouFan1tm11Jrou
• abnormal DNA repair_Fan1<tm1.1Jrou>/Fan1<tm1.1Jrou>
  http://metadb.riken.jp/0008058I129P2OlaHsdFan1tm11JrouFan1tm11JrouFan1tm11Jrou