I. Lyons, et.al., Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5., Genes & development, 1995, 9

http://rdf.ncbi.nlm.nih.gov/pubmed/7628699

I. Lyons, et.al., Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5., Genes & development, 1995, 9

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Nkx2-5<tm1Wehi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1927227

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal fetal atrioventricular canal morphology_Nkx2-5<tm1Wehi>/Nkx2-5<tm1Wehi>
  http://metadb.riken.jp/0006107I129P2OlaHsdC57BL6JC57BL10Nkx25tm1WehiNkx25tm1WehiNkx25tm1Wehi
• incomplete somite formation_Nkx2-5<tm1Wehi>/Nkx2-5<tm1Wehi>
  http://metadb.riken.jp/0001689I129P2OlaHsdC57BL6JC57BL10Nkx25tm1WehiNkx25tm1WehiNkx25tm1Wehi
• disorganized myocardium_Nkx2-5<tm1Wehi>/Nkx2-5<tm1Wehi>
  http://metadb.riken.jp/0002190I129P2OlaHsdC57BL6JC57BL10Nkx25tm1WehiNkx25tm1WehiNkx25tm1Wehi
• edema_Nkx2-5<tm1Wehi>/Nkx2-5<tm1Wehi>
  http://metadb.riken.jp/0001785I129P2OlaHsdC57BL6JC57BL10Nkx25tm1WehiNkx25tm1WehiNkx25tm1Wehi
• failure of heart looping_Nkx2-5<tm1Wehi>/Nkx2-5<tm1Wehi>
  http://metadb.riken.jp/0004251I129P2OlaHsdC57BL6JC57BL10Nkx25tm1WehiNkx25tm1WehiNkx25tm1Wehi
• abnormal somite development_Nkx2-5<tm1Wehi>/Nkx2-5<tm1Wehi>
  http://metadb.riken.jp/0001688I129P2OlaHsdC57BL6JC57BL10Nkx25tm1WehiNkx25tm1WehiNkx25tm1Wehi
• abnormal myocardium layer morphology_Nkx2-5<tm1Wehi>/Nkx2-5<tm1Wehi>
  http://metadb.riken.jp/0005329I129P2OlaHsdC57BL6JC57BL10Nkx25tm1WehiNkx25tm1WehiNkx25tm1Wehi
• abnormal sinus venosus morphology_Nkx2-5<tm1Wehi>/Nkx2-5<tm1Wehi>
  http://metadb.riken.jp/0003228I129P2OlaHsdC57BL6JC57BL10Nkx25tm1WehiNkx25tm1WehiNkx25tm1Wehi
• absent trabeculae carneae_Nkx2-5<tm1Wehi>/Nkx2-5<tm1Wehi>
  http://metadb.riken.jp/0000296I129P2OlaHsdC57BL6JC57BL10Nkx25tm1WehiNkx25tm1WehiNkx25tm1Wehi
• embryonic growth retardation_Nkx2-5<tm1Wehi>/Nkx2-5<tm1Wehi>
  http://metadb.riken.jp/0003984I129P2OlaHsdC57BL6JC57BL10Nkx25tm1WehiNkx25tm1WehiNkx25tm1Wehi
• absent atrioventricular cushions_Nkx2-5<tm1Wehi>/Nkx2-5<tm1Wehi>
  http://metadb.riken.jp/0000298I129P2OlaHsdC57BL6JC57BL10Nkx25tm1WehiNkx25tm1WehiNkx25tm1Wehi
• decreased embryo size_Nkx2-5<tm1Wehi>/Nkx2-5<tm1Wehi>
  http://metadb.riken.jp/0001698I129P2OlaHsdC57BL6JC57BL10Nkx25tm1WehiNkx25tm1WehiNkx25tm1Wehi
• abnormal heart tube morphology_Nkx2-5<tm1Wehi>/Nkx2-5<tm1Wehi>
  http://metadb.riken.jp/0000270I129P2OlaHsdC57BL6JC57BL10Nkx25tm1WehiNkx25tm1WehiNkx25tm1Wehi
• poor circulation_Nkx2-5<tm1Wehi>/Nkx2-5<tm1Wehi>
  http://metadb.riken.jp/0001633I129P2OlaHsdC57BL6JC57BL10Nkx25tm1WehiNkx25tm1WehiNkx25tm1Wehi
• embryonic lethality during organogenesis, complete penetrance_Nkx2-5<tm1Wehi>/Nkx2-5<tm1Wehi>
  http://metadb.riken.jp/0011098I129P2OlaHsdC57BL6JC57BL10Nkx25tm1WehiNkx25tm1WehiNkx25tm1Wehi
• pericardial edema_Nkx2-5<tm1Wehi>/Nkx2-5<tm1Wehi>
  http://metadb.riken.jp/0001787I129P2OlaHsdC57BL6JC57BL10Nkx25tm1WehiNkx25tm1WehiNkx25tm1Wehi
• abnormal heart shape_Nkx2-5<tm1Wehi>/Nkx2-5<tm1Wehi>
  http://metadb.riken.jp/0000277I129P2OlaHsdC57BL6JC57BL10Nkx25tm1WehiNkx25tm1WehiNkx25tm1Wehi
• abnormal heart ventricle morphology_Nkx2-5<tm1Wehi>/Nkx2-5<tm1Wehi>
  http://metadb.riken.jp/0005294I129P2OlaHsdC57BL6JC57BL10Nkx25tm1WehiNkx25tm1WehiNkx25tm1Wehi
• abnormal myogenesis_Nkx2-5<tm1Wehi>/Nkx2-5<tm1Wehi>
  http://metadb.riken.jp/0000729I129P2OlaHsdC57BL6JC57BL10Nkx25tm1WehiNkx25tm1WehiNkx25tm1Wehi
• abnormal cardiac outflow tract development_Nkx2-5<tm1Wehi>/Nkx2-5<tm1Wehi>
  http://metadb.riken.jp/0006126I129P2OlaHsdC57BL6JC57BL10Nkx25tm1WehiNkx25tm1WehiNkx25tm1Wehi

class

http://purl.org/net/cito/citesAsAuthority

• Nkx2-5<tm1Wehi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1927227

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD20854
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD20854
• CD39963
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD39963
• CD39266
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD39266
• CD19550
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD19550
• CD39631
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD39631