T. Groves, et.al., Fyn can partially substitute for Lck in T lymphocyte development., Immunity, 1996, 5

http://rdf.ncbi.nlm.nih.gov/pubmed/8934569

T. Groves, et.al., Fyn can partially substitute for Lck in T lymphocyte development., Immunity, 1996, 5

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Lck-Fyn*Y528F)5525Cjg
  http://metadb.riken.jp/db/mgi_rdf/MGI:4360310

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal single-positive T cell number_Lck<tm1Mak>/Lck<tm1Mak>
  http://metadb.riken.jp/0008081I129S2SvPasLcktm1MakLcktm1MakLcktm1Mak
• decreased T cell number_Lck<tm1Mak>/Lck<tm1Mak>
  http://metadb.riken.jp/0005018I129S2SvPasLcktm1MakLcktm1MakLcktm1Mak
• thymus hypoplasia_Fyn<tm1Rmp>/Fyn<tm1Rmp>,Lck<tm1Mak>/Lck<tm1Mak>
  http://metadb.riken.jp/0001823I129S2SvPasFyntm1RmpFyntm1RmpLcktm1MakLcktm1MakLcktm1MakFyntm1Rmp
• absent T cells_Fyn<tm1Rmp>/Fyn<tm1Rmp>,Lck<tm1Mak>/Lck<tm1Mak>
  http://metadb.riken.jp/0008070I129S2SvPasFyntm1RmpFyntm1RmpLcktm1MakLcktm1MakLcktm1MakFyntm1Rmp
• decreased gamma-delta T cell number_Lck<tm1Mak>/Lck<tm1Mak>
  http://metadb.riken.jp/0008347I129S2SvPasLcktm1MakLcktm1MakLcktm1Mak
• decreased gamma-delta T cell number_Fyn<tm1Rmp>/Fyn<tm1Rmp>
  http://metadb.riken.jp/0008347I129S2SvPasFyntm1RmpFyntm1RmpFyntm1Rmp
• decreased T cell number_Lck<tm1Mak>/Lck<tm1Mak>,Rag1<tm1Mom>/Rag1<+>,Tg(Lck-Fyn*Y528F)5525Cjg/0
  http://metadb.riken.jp/0005018I129S2SvPas129S7SvEvBrdC57BL6Lcktm1MakLcktm1MakRag1tm1MomRag1TgLckFynY528F5525Cjg0Rag1TgLckFynY528F5525CjgRag1tm1MomLcktm1Mak
• arrested T cell differentiation_Fyn<tm1Rmp>/Fyn<tm1Rmp>,Lck<tm1Mak>/Lck<tm1Mak>
  http://metadb.riken.jp/0001825I129S2SvPasFyntm1RmpFyntm1RmpLcktm1MakLcktm1MakLcktm1MakFyntm1Rmp
• abnormal T cell differentiation_Lck<tm1Mak>/Lck<tm1Mak>,Rag1<tm1Mom>/Rag1<+>,Tg(Lck-Fyn*Y528F)5525Cjg/0
  http://metadb.riken.jp/0002145I129S2SvPas129S7SvEvBrdC57BL6Lcktm1MakLcktm1MakRag1tm1MomRag1TgLckFynY528F5525Cjg0Rag1TgLckFynY528F5525CjgRag1tm1MomLcktm1Mak
• thymus hypoplasia_Lck<tm1Mak>/Lck<tm1Mak>
  http://metadb.riken.jp/0001823I129S2SvPasLcktm1MakLcktm1MakLcktm1Mak
• decreased T cell number_Fyn<tm1Rmp>/Fyn<tm1Rmp>
  http://metadb.riken.jp/0005018I129S2SvPasFyntm1RmpFyntm1RmpFyntm1Rmp

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Lck-Fyn*Y528F)5525Cjg
  http://metadb.riken.jp/db/mgi_rdf/MGI:4360310