H. Shimano, et.al., Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene., The Journal of clinical investigation, 1997, 100

http://rdf.ncbi.nlm.nih.gov/pubmed/9329978

H. Shimano, et.al., Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene., The Journal of clinical investigation, 1997, 100

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Srebf1<tm2Jdh>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177958
• Srebf1<tm1Jdh>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177773

class

http://purl.org/net/cito/citesAsAuthority

• Srebf1<tm2Jdh>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177958
• Srebf1<tm1Jdh>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177773

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased liver cholesterol level_Srebf1<tm1Jdh>/Srebf1<tm1Jdh>
  http://metadb.riken.jp/0010027I129SSvEvBrdC57BL6Srebf1tm1JdhSrebf1tm1JdhSrebf1tm1Jdh
• decreased circulating cholesterol level_Srebf1<tm2Jdh>/Srebf1<tm2Jdh>
  http://metadb.riken.jp/0005179I129SSvEvBrdC57BL6Srebf1tm2JdhSrebf1tm2JdhSrebf1tm2Jdh
• embryonic lethality during organogenesis, incomplete penetrance_Srebf1<tm1Jdh>/Srebf1<tm1Jdh>
  http://metadb.riken.jp/0011108I129SSvEvBrdC57BL6Srebf1tm1JdhSrebf1tm1JdhSrebf1tm1Jdh
• decreased survivor rate_Srebf1<tm1Jdh>/Srebf1<tm1Jdh>
  http://metadb.riken.jp/0008770I129SSvEvBrdC57BL6Srebf1tm1JdhSrebf1tm1JdhSrebf1tm1Jdh
• increased liver cholesterol level_Srebf1<tm2Jdh>/Srebf1<tm2Jdh>
  http://metadb.riken.jp/0010027I129SSvEvBrdC57BL6Srebf1tm2JdhSrebf1tm2JdhSrebf1tm2Jdh
• lethality throughout fetal growth and development, incomplete penetrance_Srebf1<tm1Jdh>/Srebf1<tm1Jdh>
  http://metadb.riken.jp/0011109I129SSvEvBrdC57BL6Srebf1tm1JdhSrebf1tm1JdhSrebf1tm1Jdh
• postnatal lethality, incomplete penetrance_Srebf1<tm2Jdh>/Srebf1<tm2Jdh>
  http://metadb.riken.jp/0011086I129SSvEvBrdC57BL6Srebf1tm2JdhSrebf1tm2JdhSrebf1tm2Jdh
• decreased circulating triglyceride level_Srebf1<tm2Jdh>/Srebf1<tm2Jdh>
  http://metadb.riken.jp/0002644I129SSvEvBrdC57BL6Srebf1tm2JdhSrebf1tm2JdhSrebf1tm2Jdh

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD02600
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD02600