C. Sirard, et.al., The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo., Genes & development, 1998, 12

http://rdf.ncbi.nlm.nih.gov/pubmed/9420335

C. Sirard, et.al., The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo., Genes & development, 1998, 12

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Smad4<tm1Mak>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1858049

class

http://purl.org/net/cito/citesAsAuthority

• Smad4<tm1Mak>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1858049

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• failure of primitive streak formation_Smad4<tm1Mak>/Smad4<tm1Mak>
  http://metadb.riken.jp/0001693EI129P2OlaHsdC57BL6JorI129P2OlaHsdC57BL6JCD1Smad4tm1MakSmad4tm1MakSmad4tm1Mak
• failure to gastrulate_Smad4<tm1Mak>/Smad4<tm1Mak>
  http://metadb.riken.jp/0001696EI129P2OlaHsdC57BL6JorI129P2OlaHsdC57BL6JCD1Smad4tm1MakSmad4tm1MakSmad4tm1Mak
• abnormal embryonic tissue morphology_Smad4<tm1Mak>/Smad4<tm1Mak>
  http://metadb.riken.jp/0002085EI129P2OlaHsdC57BL6JorI129P2OlaHsdC57BL6JCD1Smad4tm1MakSmad4tm1MakSmad4tm1Mak
• embryonic lethality between implantation and somite formation, complete penetrance_Smad4<tm1Mak>/Smad4<tm1Mak>
  http://metadb.riken.jp/0011096EI129P2OlaHsdC57BL6JorI129P2OlaHsdC57BL6JCD1Smad4tm1MakSmad4tm1MakSmad4tm1Mak
• rostral body truncation_Smad4<tm1Mak>/Smad4<tm1Mak>
  http://metadb.riken.jp/0012157EI129P2OlaHsdC57BL6JorI129P2OlaHsdC57BL6JCD1Smad4tm1MakSmad4tm1MakSmad4tm1Mak
• abnormal mesoderm development_Smad4<tm1Mak>/Smad4<tm1Mak>
  http://metadb.riken.jp/0001680EI129P2OlaHsdC57BL6JorI129P2OlaHsdC57BL6JCD1Smad4tm1MakSmad4tm1MakSmad4tm1Mak
• embryonic growth arrest_Smad4<tm1Mak>/Smad4<tm1Mak>
  http://metadb.riken.jp/0001730EI129P2OlaHsdC57BL6JorI129P2OlaHsdC57BL6JCD1Smad4tm1MakSmad4tm1MakSmad4tm1Mak
• abnormal ectoderm development_Smad4<tm1Mak>/Smad4<tm1Mak>
  http://metadb.riken.jp/0001675EI129P2OlaHsdC57BL6JorI129P2OlaHsdC57BL6JCD1Smad4tm1MakSmad4tm1MakSmad4tm1Mak
• decreased embryo size_Smad4<tm1Mak>/Smad4<tm1Mak>
  http://metadb.riken.jp/0001698EI129P2OlaHsdC57BL6JorI129P2OlaHsdC57BL6JCD1Smad4tm1MakSmad4tm1MakSmad4tm1Mak
• abnormal visceral endoderm morphology_Smad4<tm1Mak>/Smad4<tm1Mak>
  http://metadb.riken.jp/0011186EI129P2OlaHsdC57BL6JorI129P2OlaHsdC57BL6JCD1Smad4tm1MakSmad4tm1MakSmad4tm1Mak
• disorganized extraembryonic tissue_Smad4<tm1Mak>/Smad4<tm1Mak>
  http://metadb.riken.jp/0002582EI129P2OlaHsdC57BL6JorI129P2OlaHsdC57BL6JCD1Smad4tm1MakSmad4tm1MakSmad4tm1Mak
• abnormal embryonic-extraembryonic boundary morphology_Smad4<tm1Mak>/Smad4<tm1Mak>
  http://metadb.riken.jp/0003890EI129P2OlaHsdC57BL6JorI129P2OlaHsdC57BL6JCD1Smad4tm1MakSmad4tm1MakSmad4tm1Mak
• decreased cell proliferation_Smad4<tm1Mak>/Smad4<tm1Mak>
  http://metadb.riken.jp/0000352EI129P2OlaHsdC57BL6JorI129P2OlaHsdC57BL6JCD1Smad4tm1MakSmad4tm1MakSmad4tm1Mak
• absent mesoderm_Smad4<tm1Mak>/Smad4<tm1Mak>
  http://metadb.riken.jp/0001683EI129P2OlaHsdC57BL6JorI129P2OlaHsdC57BL6JCD1Smad4tm1MakSmad4tm1MakSmad4tm1Mak

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD05729
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD05729