Akiko. Nagamachi, et.al., A 5' untranslated region containing the IRES element in the Runx1 gene is required for angiogenesis, hematopoiesis and leukemogenesis in a knock-in mouse model., Developmental biology, 2010, 345

http://rdf.ncbi.nlm.nih.gov/pubmed/20647008

Akiko. Nagamachi, et.al., A 5' untranslated region containing the IRES element in the Runx1 gene is required for angiogenesis, hematopoiesis and leukemogenesis in a knock-in mouse model., Developmental biology, 2010, 345

rdfs:label

http://www.w3.org/2000/01/rdf-schema#label

• Akiko. Nagamachi, et.al., A 5' untranslated region containing the IRES element in the Runx1 gene is required for angiogenesis, hematopoiesis and leukemogenesis in a knock-in mouse model., Developmental biology, 2010, 345

article

http://www.w3.org/2000/01/rdf-schema#seeAlso

• [Blank]

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• no abnormal phenotype detected_Runx1<tm2.1(Runx1/Mecom)Homy>/Runx1<+>
  http://metadb.riken.jp/0002169B6129P2Runx1tm21Runx1MecomHomyRunx1tm21Runx1MecomHomyRunx1Runx1Runx1tm21Runx1MecomHomy
• abnormal common myeloid progenitor cell morphology_Runx1<tm1.1(RUNX1*)Homy>/Runx1<tm1.1(RUNX1*)Homy>
  http://metadb.riken.jp/0006410B6129P2Runx1tm11RUNX1HomyRunx1tm11RUNX1HomyRunx1tm11RUNX1HomyRunx1tm11RUNX1Homy
• abnormal megakaryocyte progenitor cell morphology_Runx1<tm1.1(RUNX1*)Homy>/Runx1<tm1.1(RUNX1*)Homy>
  http://metadb.riken.jp/0002413B6129P2Runx1tm11RUNX1HomyRunx1tm11RUNX1HomyRunx1tm11RUNX1HomyRunx1tm11RUNX1Homy
• lethality throughout fetal growth and development, complete penetrance_Runx1<tm1.1(RUNX1*)Homy>/Runx1<tm1.1(RUNX1*)Homy>
  http://metadb.riken.jp/0011099B6129P2Runx1tm11RUNX1HomyRunx1tm11RUNX1HomyRunx1tm11RUNX1HomyRunx1tm11RUNX1Homy
• pale liver_Runx1<tm1.1(RUNX1*)Homy>/Runx1<tm1.1(RUNX1*)Homy>
  http://metadb.riken.jp/0000603B6129P2Runx1tm11RUNX1HomyRunx1tm11RUNX1HomyRunx1tm11RUNX1HomyRunx1tm11RUNX1Homy
• impaired hematopoiesis_Runx1<tm1.1(RUNX1*)Homy>/Runx1<tm1.1(RUNX1*)Homy>
  http://metadb.riken.jp/0001606B6129P2Runx1tm11RUNX1HomyRunx1tm11RUNX1HomyRunx1tm11RUNX1HomyRunx1tm11RUNX1Homy
• hemorrhage_Runx1<tm1.1(RUNX1*)Homy>/Runx1<tm1.1(RUNX1*)Homy>
  http://metadb.riken.jp/0001914B6129P2Runx1tm11RUNX1HomyRunx1tm11RUNX1HomyRunx1tm11RUNX1HomyRunx1tm11RUNX1Homy
• abnormal pericyte morphology_Runx1<tm1.1(RUNX1*)Homy>/Runx1<tm1.1(RUNX1*)Homy>
  http://metadb.riken.jp/0003719B6129P2Runx1tm11RUNX1HomyRunx1tm11RUNX1HomyRunx1tm11RUNX1HomyRunx1tm11RUNX1Homy
• dilated vasculature_Runx1<tm1.1(RUNX1*)Homy>/Runx1<tm1.1(RUNX1*)Homy>
  http://metadb.riken.jp/0004938B6129P2Runx1tm11RUNX1HomyRunx1tm11RUNX1HomyRunx1tm11RUNX1HomyRunx1tm11RUNX1Homy
• decreased erythroid progenitor cell number_Runx1<tm1.1(RUNX1*)Homy>/Runx1<tm1.1(RUNX1*)Homy>
  http://metadb.riken.jp/0008973B6129P2Runx1tm11RUNX1HomyRunx1tm11RUNX1HomyRunx1tm11RUNX1HomyRunx1tm11RUNX1Homy
• aneurysm_Runx1<tm1.1(RUNX1*)Homy>/Runx1<tm1.1(RUNX1*)Homy>
  http://metadb.riken.jp/0003279B6129P2Runx1tm11RUNX1HomyRunx1tm11RUNX1HomyRunx1tm11RUNX1HomyRunx1tm11RUNX1Homy
• skin edema_Runx1<tm1.1(RUNX1*)Homy>/Runx1<tm1.1(RUNX1*)Homy>
  http://metadb.riken.jp/0001786B6129P2Runx1tm11RUNX1HomyRunx1tm11RUNX1HomyRunx1tm11RUNX1HomyRunx1tm11RUNX1Homy
• decreased hematopoietic cell number_Runx1<tm1.1(RUNX1*)Homy>/Runx1<tm1.1(RUNX1*)Homy>
  http://metadb.riken.jp/0011182B6129P2Runx1tm11RUNX1HomyRunx1tm11RUNX1HomyRunx1tm11RUNX1HomyRunx1tm11RUNX1Homy

Class

http://purl.org/net/cito/citesAsAuthority

• B6;129P2-Runx1<tm1Homy>
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC04608

class

http://purl.org/net/cito/citesAsAuthority

• Runx1<tm2.1(Runx1/Mecom)Homy>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4835664
• Runx1<tm1.1(RUNX1*)Homy>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4835663

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD16735
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD16735
• CD43132
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD43132
• CD15242
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD15242
• CD12792
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD12792
• CD05196
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD05196
• CD12328
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD12328
• CD13047
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD13047
• CD41633
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD41633
• CD00617
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD00617
• CD44202
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD44202

BRC マウスの系統

http://purl.org/net/cito/citesAsAuthority

• B6;129P2-Runx1<tm1Homy>
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC04608

allele

http://purl.org/net/cito/citesAsAuthority

• Runx1<tm2.1(Runx1/Mecom)Homy>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4835664
• Runx1<tm1.1(RUNX1*)Homy>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4835663