理研BRCマウスリソースカタログ
Toshiro. Moroishi, et.al., The FBXL5-IRP2 axis is integral to control of iron metabolism in vivo., Cell metabolism, 2011, 14
http://rdf.ncbi.nlm.nih.gov/pubmed/21907140
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Toshiro. Moroishi, et.al., The FBXL5-IRP2 axis is integral to control of iron metabolism in vivo., Cell metabolism, 2011, 14
rdfs:label
http://www.w3.org/2000/01/rdf-schema#label
Toshiro. Moroishi, et.al., The FBXL5-IRP2 axis is integral to control of iron metabolism in vivo., Cell metabolism, 2011, 14
article
http://www.w3.org/2000/01/rdf-schema#seeAlso
[Blank]
class
http://purl.org/net/cito/citesAsAuthority
Fbxl5<tm1Kei>
http://metadb.riken.jp/db/mgi_rdf/MGI:5295288
Fbxl5<tm2.1Kei>
http://metadb.riken.jp/db/mgi_rdf/MGI:5295289
表現型アノテーション
http://purl.org/net/cito/citesAsAuthority
liver hemorrhage_Fbxl5<tm2.1Kei>/Fbxl5<tm2.1Kei>,Tg(Alb-cre)21Mgn/0
http://metadb.riken.jp/0003888IC57BL6DBAFbxl5tm21KeiFbxl5tm21KeiTgAlbcre21Mgn0TgAlbcre21MgnFbxl5tm21Kei
abnormal iron level_Fbxl5<tm2.1Kei>/Fbxl5<tm2.1Kei>
http://metadb.riken.jp/0001770IC57BL6Fbxl5tm21KeiFbxl5tm21KeiFbxl5tm21Kei
hepatic steatosis_Fbxl5<tm2.1Kei>/Fbxl5<tm2.1Kei>,Tg(Alb-cre)21Mgn/0
http://metadb.riken.jp/0002628IC57BL6DBAFbxl5tm21KeiFbxl5tm21KeiTgAlbcre21Mgn0TgAlbcre21MgnFbxl5tm21Kei
increased liver iron level_Fbxl5<tm2.1Kei>/Fbxl5<tm2.1Kei>,Tg(Alb-cre)21Mgn/0
http://metadb.riken.jp/0008807IC57BL6DBAFbxl5tm21KeiFbxl5tm21KeiTgAlbcre21Mgn0TgAlbcre21MgnFbxl5tm21Kei
increased sensitivity to induced morbidity/mortality_Fbxl5<tm2.1Kei>/Fbxl5<tm2.1Kei>,Tg(Alb-cre)21Mgn/0
http://metadb.riken.jp/0009763IC57BL6DBAFbxl5tm21KeiFbxl5tm21KeiTgAlbcre21Mgn0TgAlbcre21MgnFbxl5tm21Kei
increased circulating aspartate transaminase level_Fbxl5<tm2.1Kei>/Fbxl5<tm2.1Kei>,Tg(Alb-cre)21Mgn/0
http://metadb.riken.jp/0005343IC57BL6DBAFbxl5tm21KeiFbxl5tm21KeiTgAlbcre21Mgn0TgAlbcre21MgnFbxl5tm21Kei
decreased mean corpuscular hemoglobin_Ireb2<tm1Roua>/Ireb2<tm1Roua>
http://metadb.riken.jp/0005562B6CgIreb2tm1RouaIreb2tm1RouaIreb2tm1RouaIreb2tm1Roua
hemorrhage_Fbxl5<tm1Kei>/Fbxl5<tm1Kei>
http://metadb.riken.jp/0001914B6CgFbxl5tm1KeiFbxl5tm1KeiFbxl5tm1KeiFbxl5tm1Kei
abnormal iron level_Fbxl5<tm1Kei>/Fbxl5<tm1Kei>
http://metadb.riken.jp/0001770B6CgFbxl5tm1KeiFbxl5tm1KeiFbxl5tm1KeiFbxl5tm1Kei
increased circulating iron level_Fbxl5<tm1Kei>/Fbxl5<tm1Kei>,Ireb2<tm1Roua>/Ireb2<tm1Roua>
http://metadb.riken.jp/0008810B6CgFbxl5tm1KeiIreb2tm1RouaFbxl5tm1KeiFbxl5tm1KeiIreb2tm1RouaIreb2tm1RouaFbxl5tm1KeiIreb2tm1Roua
liver failure_Fbxl5<tm2.1Kei>/Fbxl5<tm2.1Kei>,Tg(Alb-cre)21Mgn/0
http://metadb.riken.jp/0003326IC57BL6DBAFbxl5tm21KeiFbxl5tm21KeiTgAlbcre21Mgn0TgAlbcre21MgnFbxl5tm21Kei
increased circulating iron level_Fbxl5<tm2.1Kei>/Fbxl5<tm2.1Kei>,Tg(Alb-cre)21Mgn/0
http://metadb.riken.jp/0008810IC57BL6DBAFbxl5tm21KeiFbxl5tm21KeiTgAlbcre21Mgn0TgAlbcre21MgnFbxl5tm21Kei
decreased hematocrit_Ireb2<tm1Roua>/Ireb2<tm1Roua>
http://metadb.riken.jp/0000208B6CgIreb2tm1RouaIreb2tm1RouaIreb2tm1RouaIreb2tm1Roua
oxidative stress_Fbxl5<tm2.1Kei>/Fbxl5<tm2.1Kei>
http://metadb.riken.jp/0003674IC57BL6Fbxl5tm21KeiFbxl5tm21KeiFbxl5tm21Kei
decreased mean corpuscular volume_Ireb2<tm1Roua>/Ireb2<tm1Roua>
http://metadb.riken.jp/0002591B6CgIreb2tm1RouaIreb2tm1RouaIreb2tm1RouaIreb2tm1Roua
decreased mean corpuscular volume_Fbxl5<tm1Kei>/Fbxl5<tm1Kei>,Ireb2<tm1Roua>/Ireb2<tm1Roua>
http://metadb.riken.jp/0002591B6CgFbxl5tm1KeiIreb2tm1RouaFbxl5tm1KeiFbxl5tm1KeiIreb2tm1RouaIreb2tm1RouaFbxl5tm1KeiIreb2tm1Roua
decreased circulating unsaturated transferrin level_Fbxl5<tm2.1Kei>/Fbxl5<tm2.1Kei>,Tg(Alb-cre)21Mgn/0
http://metadb.riken.jp/0011897IC57BL6DBAFbxl5tm21KeiFbxl5tm21KeiTgAlbcre21Mgn0TgAlbcre21MgnFbxl5tm21Kei
abnormal circulating enzyme level_Fbxl5<tm2.1Kei>/Fbxl5<tm2.1Kei>,Tg(Alb-cre)21Mgn/0
http://metadb.riken.jp/0001570IC57BL6DBAFbxl5tm21KeiFbxl5tm21KeiTgAlbcre21Mgn0TgAlbcre21MgnFbxl5tm21Kei
decreased hematocrit_Fbxl5<tm1Kei>/Fbxl5<tm1Kei>,Ireb2<tm1Roua>/Ireb2<tm1Roua>
http://metadb.riken.jp/0000208B6CgFbxl5tm1KeiIreb2tm1RouaFbxl5tm1KeiFbxl5tm1KeiIreb2tm1RouaIreb2tm1RouaFbxl5tm1KeiIreb2tm1Roua
abnormal mitochondrial physiology_Fbxl5<tm2.1Kei>/Fbxl5<tm2.1Kei>
http://metadb.riken.jp/0006036IC57BL6Fbxl5tm21KeiFbxl5tm21KeiFbxl5tm21Kei
oxidative stress_Fbxl5<tm1Kei>/Fbxl5<tm1Kei>
http://metadb.riken.jp/0003674B6CgFbxl5tm1KeiFbxl5tm1KeiFbxl5tm1KeiFbxl5tm1Kei
liver inflammation_Fbxl5<tm2.1Kei>/Fbxl5<tm2.1Kei>,Tg(Alb-cre)21Mgn/0
http://metadb.riken.jp/0001860IC57BL6DBAFbxl5tm21KeiFbxl5tm21KeiTgAlbcre21Mgn0TgAlbcre21MgnFbxl5tm21Kei
internal hemorrhage_Fbxl5<tm1Kei>/Fbxl5<tm1Kei>
http://metadb.riken.jp/0001634B6CgFbxl5tm1KeiFbxl5tm1KeiFbxl5tm1KeiFbxl5tm1Kei
decreased mean corpuscular hemoglobin concentration_Ireb2<tm1Roua>/Ireb2<tm1Roua>
http://metadb.riken.jp/0005642B6CgIreb2tm1RouaIreb2tm1RouaIreb2tm1RouaIreb2tm1Roua
abnormal liver physiology_Fbxl5<tm2.1Kei>/Fbxl5<tm2.1Kei>,Tg(Alb-cre)21Mgn/0
http://metadb.riken.jp/0000609IC57BL6DBAFbxl5tm21KeiFbxl5tm21KeiTgAlbcre21Mgn0TgAlbcre21MgnFbxl5tm21Kei
microcytosis_Fbxl5<tm1Kei>/Fbxl5<tm1Kei>,Ireb2<tm1Roua>/Ireb2<tm1Roua>
http://metadb.riken.jp/0002813B6CgFbxl5tm1KeiIreb2tm1RouaFbxl5tm1KeiFbxl5tm1KeiIreb2tm1RouaIreb2tm1RouaFbxl5tm1KeiIreb2tm1Roua
embryonic growth retardation_Fbxl5<tm1Kei>/Fbxl5<tm1Kei>
http://metadb.riken.jp/0003984B6CgFbxl5tm1KeiFbxl5tm1KeiFbxl5tm1KeiFbxl5tm1Kei
decreased circulating unsaturated transferrin level_Fbxl5<tm1Kei>/Fbxl5<tm1Kei>,Ireb2<tm1Roua>/Ireb2<tm1Roua>
http://metadb.riken.jp/0011897B6CgFbxl5tm1KeiIreb2tm1RouaFbxl5tm1KeiFbxl5tm1KeiIreb2tm1RouaIreb2tm1RouaFbxl5tm1KeiIreb2tm1Roua
increased embryonic tissue cell apoptosis_Fbxl5<tm1Kei>/Fbxl5<tm1Kei>
http://metadb.riken.jp/0013504B6CgFbxl5tm1KeiFbxl5tm1KeiFbxl5tm1KeiFbxl5tm1Kei
abnormal extraembryonic tissue physiology_Fbxl5<tm1Kei>/Fbxl5<tm1Kei>
http://metadb.riken.jp/0004264B6CgFbxl5tm1KeiFbxl5tm1KeiFbxl5tm1KeiFbxl5tm1Kei
embryonic lethality between somite formation and embryo turning, complete penetrance_Fbxl5<tm1Kei>/Fbxl5<tm1Kei>
http://metadb.riken.jp/0011097B6CgFbxl5tm1KeiFbxl5tm1KeiFbxl5tm1KeiFbxl5tm1Kei
decreased hemoglobin content_Ireb2<tm1Roua>/Ireb2<tm1Roua>
http://metadb.riken.jp/0002874B6CgIreb2tm1RouaIreb2tm1RouaIreb2tm1RouaIreb2tm1Roua
microcytosis_Ireb2<tm1Roua>/Ireb2<tm1Roua>
http://metadb.riken.jp/0002813B6CgIreb2tm1RouaIreb2tm1RouaIreb2tm1RouaIreb2tm1Roua
pale liver_Fbxl5<tm2.1Kei>/Fbxl5<tm2.1Kei>,Tg(Alb-cre)21Mgn/0
http://metadb.riken.jp/0000603IC57BL6DBAFbxl5tm21KeiFbxl5tm21KeiTgAlbcre21Mgn0TgAlbcre21MgnFbxl5tm21Kei
abnormal hepatocyte morphology_Fbxl5<tm2.1Kei>/Fbxl5<tm2.1Kei>,Tg(Alb-cre)21Mgn/0
http://metadb.riken.jp/0000607IC57BL6DBAFbxl5tm21KeiFbxl5tm21KeiTgAlbcre21Mgn0TgAlbcre21MgnFbxl5tm21Kei
increased lactate dehydrogenase level_Fbxl5<tm2.1Kei>/Fbxl5<tm2.1Kei>,Tg(Alb-cre)21Mgn/0
http://metadb.riken.jp/0002944IC57BL6DBAFbxl5tm21KeiFbxl5tm21KeiTgAlbcre21Mgn0TgAlbcre21MgnFbxl5tm21Kei
increased partial thromboplastin time_Fbxl5<tm2.1Kei>/Fbxl5<tm2.1Kei>,Tg(Alb-cre)21Mgn/0
http://metadb.riken.jp/0012359IC57BL6DBAFbxl5tm21KeiFbxl5tm21KeiTgAlbcre21Mgn0TgAlbcre21MgnFbxl5tm21Kei
abnormal blood coagulation_Fbxl5<tm2.1Kei>/Fbxl5<tm2.1Kei>,Tg(Alb-cre)21Mgn/0
http://metadb.riken.jp/0002551IC57BL6DBAFbxl5tm21KeiFbxl5tm21KeiTgAlbcre21Mgn0TgAlbcre21MgnFbxl5tm21Kei
increased prothrombin time_Fbxl5<tm2.1Kei>/Fbxl5<tm2.1Kei>,Tg(Alb-cre)21Mgn/0
http://metadb.riken.jp/0012356IC57BL6DBAFbxl5tm21KeiFbxl5tm21KeiTgAlbcre21Mgn0TgAlbcre21MgnFbxl5tm21Kei
decreased mean corpuscular hemoglobin concentration_Fbxl5<tm1Kei>/Fbxl5<tm1Kei>,Ireb2<tm1Roua>/Ireb2<tm1Roua>
http://metadb.riken.jp/0005642B6CgFbxl5tm1KeiIreb2tm1RouaFbxl5tm1KeiFbxl5tm1KeiIreb2tm1RouaIreb2tm1RouaFbxl5tm1KeiIreb2tm1Roua
decreased liver iron level_Fbxl5<tm1Kei>/Fbxl5<tm1Kei>,Ireb2<tm1Roua>/Ireb2<tm1Roua>
http://metadb.riken.jp/0008743B6CgFbxl5tm1KeiIreb2tm1RouaFbxl5tm1KeiFbxl5tm1KeiIreb2tm1RouaIreb2tm1RouaFbxl5tm1KeiIreb2tm1Roua
abnormal embryo development_Fbxl5<tm1Kei>/Fbxl5<tm1Kei>
http://metadb.riken.jp/0001672B6CgFbxl5tm1KeiFbxl5tm1KeiFbxl5tm1KeiFbxl5tm1Kei
decreased hemoglobin content_Fbxl5<tm1Kei>/Fbxl5<tm1Kei>,Ireb2<tm1Roua>/Ireb2<tm1Roua>
http://metadb.riken.jp/0002874B6CgFbxl5tm1KeiIreb2tm1RouaFbxl5tm1KeiFbxl5tm1KeiIreb2tm1RouaIreb2tm1RouaFbxl5tm1KeiIreb2tm1Roua
abnormal ectoplacental cone morphology_Fbxl5<tm1Kei>/Fbxl5<tm1Kei>
http://metadb.riken.jp/0005032B6CgFbxl5tm1KeiFbxl5tm1KeiFbxl5tm1KeiFbxl5tm1Kei
decreased spleen iron level_Ireb2<tm1Roua>/Ireb2<tm1Roua>
http://metadb.riken.jp/0008808B6CgIreb2tm1RouaIreb2tm1RouaIreb2tm1RouaIreb2tm1Roua
increased circulating alanine transaminase level_Fbxl5<tm2.1Kei>/Fbxl5<tm2.1Kei>,Tg(Alb-cre)21Mgn/0
http://metadb.riken.jp/0002941IC57BL6DBAFbxl5tm21KeiFbxl5tm21KeiTgAlbcre21Mgn0TgAlbcre21MgnFbxl5tm21Kei
decreased mean corpuscular hemoglobin_Fbxl5<tm1Kei>/Fbxl5<tm1Kei>,Ireb2<tm1Roua>/Ireb2<tm1Roua>
http://metadb.riken.jp/0005562B6CgFbxl5tm1KeiIreb2tm1RouaFbxl5tm1KeiFbxl5tm1KeiIreb2tm1RouaIreb2tm1RouaFbxl5tm1KeiIreb2tm1Roua
increased liver iron level_Ireb2<tm1Roua>/Ireb2<tm1Roua>
http://metadb.riken.jp/0008807B6CgIreb2tm1RouaIreb2tm1RouaIreb2tm1RouaIreb2tm1Roua
表現型アノテーション
http://purl.org/net/cito/citesAsAuthority
hepatic steatosis in RBRC06390
http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1016085
abnormal iron level in RBRC06390
http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1016072
pale liver in RBRC06390
http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1016086
increased circulating alanine transaminase level in RBRC06390
http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1016075
abnormal liver physiology in RBRC06390
http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1016087
abnormal blood coagulation in RBRC06390
http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1016078
liver inflammation in RBRC06390
http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1016088
decreased circulating unsaturated transferrin level in RBRC06390
http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1016077
increased lactate dehydrogenase level in RBRC06390
http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1016081
increased liver iron level in RBRC06390
http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1016082
liver hemorrhage in RBRC06390
http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1016083
oxidative stress in RBRC06390
http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1016071
abnormal circulating enzyme level in RBRC06390
http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1016074
abnormal hepatocyte morphology in RBRC06390
http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1016084
liver failure in RBRC06390
http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1016089
increased circulating iron level in RBRC06390
http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1016073
increased circulating aspartate transaminase level in RBRC06390
http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1016076
increased partial thromboplastin time in RBRC06390
http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1016079
abnormal mitochondrial physiology in RBRC06390
http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1016070
increased prothrombin time in RBRC06390
http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1016080
Class
http://purl.org/net/cito/citesAsAuthority
B6;129P2-Fbxl5<tm2.1Kei>
http://metadb.riken.jp/db/rikenbrc_mouse/RBRC06390
allele
http://purl.org/net/cito/citesAsAuthority
Fbxl5<tm1Kei>
http://metadb.riken.jp/db/mgi_rdf/MGI:5295288
Fbxl5<tm2.1Kei>
http://metadb.riken.jp/db/mgi_rdf/MGI:5295289
BRC マウスの系統
http://purl.org/net/cito/citesAsAuthority
B6;129P2-Fbxl5<tm2.1Kei>
http://metadb.riken.jp/db/rikenbrc_mouse/RBRC06390
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