Toru. Atsumi, et.al., A point mutation of Tyr-759 in interleukin 6 family cytokine receptor subunit gp130 causes autoimmune arthritis., The Journal of experimental medicine, 2002, 196

http://rdf.ncbi.nlm.nih.gov/pubmed/12370259

Toru. Atsumi, et.al., A point mutation of Tyr-759 in interleukin 6 family cytokine receptor subunit gp130 causes autoimmune arthritis., The Journal of experimental medicine, 2002, 196

pubmed

BRC マウスの系統

http://purl.org/net/cito/citesAsAuthority

• C57BL/6gp130FxxQ/FxxQ
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC01531
• C57BL(N8)759F759
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC01532
• C57BL/6 gp130WH/WH
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC01530

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased IgG1 level in RBRC01530
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1018110
• increased IgA level in RBRC01530
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1018109
• rheumatoid arthritis in RBRC01532
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002912
• decreased double-positive T cell number in RBRC01530
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1018105
• increased neutrophil cell number in RBRC01530
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1018106
• increased activated T cell number in RBRC01532
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002907
• increased anti-double stranded DNA antibody level in RBRC01530
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1018117
• increased IgG2b level in RBRC01530
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1018112
• increased autoantibody level in RBRC01532
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002913
• increased activated T cell number in RBRC01530
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1018107
• decreased double-positive T cell number in RBRC01532
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002924
• increased single-positive T cell number in RBRC01530
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1018108
• increased neutrophil cell number in RBRC01532
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002904
• abnormal thymocyte activation in RBRC01530
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1018114
• abnormal thymocyte activation in RBRC01532
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002915
• increased IgG2a level in RBRC01532
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010487
• abnormal T cell clonal deletion in RBRC01532
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002920
• increased IgG1 level in RBRC01532
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002931
• abnormal T cell activation in RBRC01532
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002906
• increased anti-nuclear antigen antibody level in RBRC01530
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1018116
• increased anti-double stranded DNA antibody level in RBRC01532
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002917
• increased IgG2a level in RBRC01530
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1018111
• increased IgG2b level in RBRC01532
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1010488
• increased anti-single stranded DNA antibody level in RBRC01532
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002918
• increased single-positive T cell number in RBRC01532
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002928
• increased double-negative T cell number in RBRC01532
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002923
• increased IgA level in RBRC01532
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002910
• rheumatoid arthritis in RBRC01530
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1018101
• increased anti-single stranded DNA antibody level in RBRC01530
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1018118
• increased anti-nuclear antigen antibody level in RBRC01532
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002919
• osteoporosis in RBRC01530
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1018102
• osteoporosis in RBRC01532
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1002903
• abnormal T cell activation in RBRC01530
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1018113
• abnormal T cell clonal deletion in RBRC01530
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1018103
• increased double-negative T cell number in RBRC01530
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1018104
• increased autoantibody level in RBRC01530
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1018115

Class

http://purl.org/net/cito/citesAsAuthority

• C57BL/6gp130FxxQ/FxxQ
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC01531
• C57BL(N8)759F759
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC01532
• C57BL/6 gp130WH/WH
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC01530

article

http://www.w3.org/2000/01/rdf-schema#seeAlso

• [Blank]
• [Blank]
• [Blank]

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased anti-double stranded DNA antibody level_Il6st<tm1Thir>/Il6st<tm1Thir>
  http://metadb.riken.jp/0004762I129C57BL6Il6sttm1ThirIl6sttm1ThirIl6sttm1Thir
• abnormal thymocyte activation_Il6st<tm1Thir>/Il6st<tm1Thir>
  http://metadb.riken.jp/0003850I129C57BL6Il6sttm1ThirIl6sttm1ThirIl6sttm1Thir
• increased double-negative T cell number_Il6st<tm1Thir>/Il6st<tm1Thir>
  http://metadb.riken.jp/0005090I129C57BL6Il6sttm1ThirIl6sttm1ThirIl6sttm1Thir
• increased anti-nuclear antigen antibody level_Il6st<tm1Thir>/Il6st<tm1Thir>
  http://metadb.riken.jp/0004794I129C57BL6Il6sttm1ThirIl6sttm1ThirIl6sttm1Thir
• rheumatoid arthritis_Il6st<tm1Thir>/Il6st<tm1Thir>
  http://metadb.riken.jp/0003561I129C57BL6Il6sttm1ThirIl6sttm1ThirIl6sttm1Thir
• abnormal T cell clonal deletion_Il6st<tm1Thir>/Il6st<tm1Thir>
  http://metadb.riken.jp/0005002I129C57BL6Il6sttm1ThirIl6sttm1ThirIl6sttm1Thir
• osteoporosis_Il6st<tm1Thir>/Il6st<tm1Thir>
  http://metadb.riken.jp/0000066I129C57BL6Il6sttm1ThirIl6sttm1ThirIl6sttm1Thir
• increased anti-single stranded DNA antibody level_Il6st<tm1Thir>/Il6st<tm1Thir>
  http://metadb.riken.jp/0004771I129C57BL6Il6sttm1ThirIl6sttm1ThirIl6sttm1Thir
• abnormal negative T cell selection_Il6st<tm1Thir>/Il6st<tm1Thir>,Tg(TcraH-Y,TcrbH-Y)71Vbo/?
  http://metadb.riken.jp/0004918I129C57BL6DBAIl6sttm1ThirIl6sttm1ThirTgTcraHYTcrbHY71VboIl6sttm1ThirTgTcraHYTcrbHY71Vbo
• increased autoantibody level_Il6st<tm1Thir>/Il6st<tm1Thir>
  http://metadb.riken.jp/0003725I129C57BL6Il6sttm1ThirIl6sttm1ThirIl6sttm1Thir
• increased neutrophil cell number_Il6st<tm1Thir>/Il6st<tm1Thir>
  http://metadb.riken.jp/0000219I129C57BL6Il6sttm1ThirIl6sttm1ThirIl6sttm1Thir
• decreased double-positive T cell number_Il6st<tm1Thir>/Il6st<tm1Thir>
  http://metadb.riken.jp/0005092I129C57BL6Il6sttm1ThirIl6sttm1ThirIl6sttm1Thir
• increased IgG2b level_Il6st<tm1Thir>/Il6st<tm1Thir>
  http://metadb.riken.jp/0008501I129C57BL6Il6sttm1ThirIl6sttm1ThirIl6sttm1Thir
• increased IgA level_Il6st<tm1Thir>/Il6st<tm1Thir>
  http://metadb.riken.jp/0002495I129C57BL6Il6sttm1ThirIl6sttm1ThirIl6sttm1Thir
• increased IgG2a level_Il6st<tm1Thir>/Il6st<tm1Thir>
  http://metadb.riken.jp/0008500I129C57BL6Il6sttm1ThirIl6sttm1ThirIl6sttm1Thir
• increased single-positive T cell number_Il6st<tm1Thir>/Il6st<tm1Thir>
  http://metadb.riken.jp/0008082I129C57BL6Il6sttm1ThirIl6sttm1ThirIl6sttm1Thir
• abnormal T cell activation_Il6st<tm1Thir>/Il6st<tm1Thir>
  http://metadb.riken.jp/0001828I129C57BL6Il6sttm1ThirIl6sttm1ThirIl6sttm1Thir
• increased IgG1 level_Il6st<tm1Thir>/Il6st<tm1Thir>
  http://metadb.riken.jp/0008499I129C57BL6Il6sttm1ThirIl6sttm1ThirIl6sttm1Thir
• increased activated T cell number_Il6st<tm1Thir>/Il6st<tm1Thir>
  http://metadb.riken.jp/0001829I129C57BL6Il6sttm1ThirIl6sttm1ThirIl6sttm1Thir

article

http://www.w3.org/2000/01/rdf-schema#seeAlso

• [Blank]
• [Blank]
• [Blank]