Zhenyue. Hao, et.al., T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis., The Journal of experimental medicine, 2004, 199

http://rdf.ncbi.nlm.nih.gov/pubmed/15148335

Zhenyue. Hao, et.al., T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis., The Journal of experimental medicine, 2004, 199

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal immune system morphology in RBRC06464
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014653
• abnormal immune system morphology in RBRC02886
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014508
• abnormal immune system morphology in RBRC03105
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014535
• abnormal immune system morphology in RBRC02885
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014507
• abnormal immune system morphology in RBRC02442
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1014485

allele

http://purl.org/net/cito/citesAsAuthority

• Fas<tm1.1Cgn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3690544
• Fas<tm1Cgn>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3690464

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased B cell number_Fas<tm1Cgn>/Fas<tm1Cgn>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0005017B6CgFastm1CgnTgCd4cre1CwiFastm1CgnFastm1CgnTgCd4cre1Cwi0TgCd4cre1CwiFastm1Cgn
• increased anti-single stranded DNA antibody level_Cd19<tm1(cre)Cgn>/Cd19<+>,Fas<tm1Cgn>/Fas<tm1Cgn>
  http://metadb.riken.jp/0004771B6CgCd19tm1creCgnFastm1CgnCd19tm1creCgnCd19Fastm1CgnFastm1CgnCd19Fastm1CgnCd19tm1creCgn
• enlarged spleen_Fas<tm1Cgn>/Fas<tm1Cgn>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0000691B6CgFastm1CgnTgCd4cre1CwiFastm1CgnFastm1CgnTgCd4cre1Cwi0TgCd4cre1CwiFastm1Cgn
• kidney inflammation_Fas<tm1Cgn>/Fas<tm1Cgn>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0001859B6CgFastm1CgnTgCd4cre1CwiFastm1CgnFastm1CgnTgCd4cre1Cwi0TgCd4cre1CwiFastm1Cgn
• lung inflammation_Fas<tm1Cgn>/Fas<tm1Cgn>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0001861B6CgFastm1CgnTgCd4cre1CwiFastm1CgnFastm1CgnTgCd4cre1Cwi0TgCd4cre1CwiFastm1Cgn
• abnormal immune system morphology_Fas<lpr>/Fas<tm1.1Cgn>
  http://metadb.riken.jp/0000685IC57BL6MRLFaslprFastm11CgnFaslprFastm11Cgn
• enlarged lymph nodes_Cd19<tm1(cre)Cgn>/Cd19<+>,Fas<lpr>/Fas<tm1Cgn>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0000702I129P2OlaHsdC57BL6DBA2MRLCd19tm1creCgnCd19FaslprFastm1CgnTgCd4cre1Cwi0TgCd4cre1CwiCd19tm1creCgnFaslprFastm1CgnCd19
• lymph node hypoplasia_Fas<tm1Cgn>/Fas<tm1Cgn>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008101B6CgFastm1CgnTgCd4cre1CwiFastm1CgnFastm1CgnTgCd4cre1Cwi0TgCd4cre1CwiFastm1Cgn
• enlarged spleen_Fas<tm1.1Cgn>/Fas<tm1.1Cgn>
  http://metadb.riken.jp/0000691IC57BL6Fastm11CgnFastm11CgnFastm11Cgn
• increased anti-single stranded DNA antibody level_Cd19<tm1(cre)Cgn>/Cd19<+>,Fas<tm1Cgn>/Fas<tm1Cgn>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0004771B6CgCd19tm1creCgnFastm1CgnTgCd4cre1CwiCd19tm1creCgnCd19Fastm1CgnFastm1CgnTgCd4cre1Cwi0Fastm1CgnCd19TgCd4cre1CwiCd19tm1creCgn
• abnormal immune system organ morphology_Fas<tm1Cgn>/Fas<tm1Cgn>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0002722B6CgFastm1CgnTgCd4cre1CwiFastm1CgnFastm1CgnTgCd4cre1Cwi0TgCd4cre1CwiFastm1Cgn
• enlarged spleen_Cd19<tm1(cre)Cgn>/Cd19<+>,Fas<lpr>/Fas<tm1Cgn>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0000691I129P2OlaHsdC57BL6DBA2MRLCd19tm1creCgnCd19FaslprFastm1CgnTgCd4cre1Cwi0TgCd4cre1CwiCd19tm1creCgnFaslprFastm1CgnCd19
• enlarged spleen_Fas<tm1Cgn>/Fas<tm1Cgn>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000691B6CgFastm1CgnTgMx1cre1CgnFastm1CgnFastm1CgnTgMx1cre1Cgn0TgMx1cre1CgnFastm1Cgn
• increased double-negative T cell number_Fas<lpr>/Fas<tm1Cgn>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0005090IC57BL6DBA2MRLFaslprFastm1CgnTgCd4cre1Cwi0FaslprFastm1CgnTgCd4cre1Cwi
• liver inflammation_Fas<tm1Cgn>/Fas<tm1Cgn>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0001860B6CgFastm1CgnTgCd4cre1CwiFastm1CgnFastm1CgnTgCd4cre1Cwi0TgCd4cre1CwiFastm1Cgn
• abnormal immune system morphology_Fas<tm1.1Cgn>/Fas<tm1.1Cgn>
  http://metadb.riken.jp/0000685IC57BL6Fastm11CgnFastm11CgnFastm11Cgn
• increased memory T cell number_Fas<tm1Cgn>/Fas<tm1Cgn>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008049B6CgFastm1CgnTgCd4cre1CwiFastm1CgnFastm1CgnTgCd4cre1Cwi0TgCd4cre1CwiFastm1Cgn
• increased activated T cell number_Fas<tm1Cgn>/Fas<tm1Cgn>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0001829B6CgFastm1CgnTgCd4cre1CwiFastm1CgnFastm1CgnTgCd4cre1Cwi0TgCd4cre1CwiFastm1Cgn
• pulmonary fibrosis_Fas<tm1Cgn>/Fas<tm1Cgn>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0006050B6CgFastm1CgnTgCd4cre1CwiFastm1CgnFastm1CgnTgCd4cre1Cwi0TgCd4cre1CwiFastm1Cgn
• enlarged lymph nodes_Fas<lpr>/Fas<tm1Cgn>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0000702IC57BL6DBA2MRLFaslprFastm1CgnTgCd4cre1Cwi0FaslprFastm1CgnTgCd4cre1Cwi
• abnormal thymus involution_Fas<tm1Cgn>/Fas<tm1Cgn>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0001824B6CgFastm1CgnTgCd4cre1CwiFastm1CgnFastm1CgnTgCd4cre1Cwi0TgCd4cre1CwiFastm1Cgn
• weight loss_Fas<tm1Cgn>/Fas<tm1Cgn>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0001263B6CgFastm1CgnTgCd4cre1CwiFastm1CgnFastm1CgnTgCd4cre1Cwi0TgCd4cre1CwiFastm1Cgn
• enlarged lymph nodes_Fas<tm1.1Cgn>/Fas<tm1.1Cgn>
  http://metadb.riken.jp/0000702IC57BL6Fastm11CgnFastm11CgnFastm11Cgn
• increased double-negative T cell number_Fas<tm1Cgn>/Fas<tm1Cgn>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0005090B6CgFastm1CgnTgCd4cre1CwiFastm1CgnFastm1CgnTgCd4cre1Cwi0TgCd4cre1CwiFastm1Cgn
• increased T cell apoptosis_Fas<tm1Cgn>/Fas<tm1Cgn>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0006413B6CgFastm1CgnTgCd4cre1CwiFastm1CgnFastm1CgnTgCd4cre1Cwi0TgCd4cre1CwiFastm1Cgn
• abnormal immune system cell morphology_Fas<tm1Cgn>/Fas<tm1Cgn>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0000716B6CgFastm1CgnTgCd4cre1CwiFastm1CgnFastm1CgnTgCd4cre1Cwi0TgCd4cre1CwiFastm1Cgn
• enlarged spleen_Cd19<tm1(cre)Cgn>/Cd19<+>,Fas<lpr>/Fas<tm1Cgn>
  http://metadb.riken.jp/0000691I129P2OlaHsdC57BL6MRLCd19tm1creCgnCd19FaslprFastm1CgnCd19tm1creCgnFaslprFastm1CgnCd19
• lymph node hypoplasia_Fas<tm1Cgn>/Fas<tm1Cgn>,Tg(Lck-cre)I57Jxm/0
  http://metadb.riken.jp/0008101B6CgFastm1CgnTgLckcreI57JxmFastm1CgnFastm1CgnTgLckcreI57Jxm0TgLckcreI57JxmFastm1Cgn
• enlarged lymph nodes_Cd19<tm1(cre)Cgn>/Cd19<+>,Fas<lpr>/Fas<tm1Cgn>
  http://metadb.riken.jp/0000702I129P2OlaHsdC57BL6MRLCd19tm1creCgnCd19FaslprFastm1CgnCd19tm1creCgnFaslprFastm1CgnCd19
• enlarged spleen_Fas<lpr>/Fas<tm1.1Cgn>
  http://metadb.riken.jp/0000691IC57BL6MRLFaslprFastm11CgnFaslprFastm11Cgn
• increased anti-single stranded DNA antibody level_Fas<tm1Cgn>/Fas<tm1Cgn>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0004771B6CgFastm1CgnTgCd4cre1CwiFastm1CgnFastm1CgnTgCd4cre1Cwi0TgCd4cre1CwiFastm1Cgn
• enlarged lymph nodes_Fas<lpr>/Fas<tm1.1Cgn>
  http://metadb.riken.jp/0000702IC57BL6MRLFaslprFastm11CgnFaslprFastm11Cgn
• enlarged spleen_Fas<lpr>/Fas<tm1Cgn>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0000691IC57BL6DBA2MRLFaslprFastm1CgnTgCd4cre1Cwi0FaslprFastm1CgnTgCd4cre1Cwi
• increased inflammatory response_Fas<tm1Cgn>/Fas<tm1Cgn>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0001846B6CgFastm1CgnTgCd4cre1CwiFastm1CgnFastm1CgnTgCd4cre1Cwi0TgCd4cre1CwiFastm1Cgn
• enlarged lymph nodes_Fas<tm1Cgn>/Fas<tm1Cgn>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000702B6CgFastm1CgnTgMx1cre1CgnFastm1CgnFastm1CgnTgMx1cre1Cgn0TgMx1cre1CgnFastm1Cgn
• increased double-negative T cell number_Cd19<tm1(cre)Cgn>/Cd19<+>,Fas<lpr>/Fas<tm1Cgn>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0005090I129P2OlaHsdC57BL6DBA2MRLCd19tm1creCgnCd19FaslprFastm1CgnTgCd4cre1Cwi0TgCd4cre1CwiCd19tm1creCgnFaslprFastm1CgnCd19
• spleen hypoplasia_Fas<tm1Cgn>/Fas<tm1Cgn>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0000694B6CgFastm1CgnTgCd4cre1CwiFastm1CgnFastm1CgnTgCd4cre1Cwi0TgCd4cre1CwiFastm1Cgn
• alveolitis_Fas<tm1Cgn>/Fas<tm1Cgn>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0010922B6CgFastm1CgnTgCd4cre1CwiFastm1CgnFastm1CgnTgCd4cre1Cwi0TgCd4cre1CwiFastm1Cgn
• decreased T cell number_Fas<tm1Cgn>/Fas<tm1Cgn>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0005018B6CgFastm1CgnTgCd4cre1CwiFastm1CgnFastm1CgnTgCd4cre1Cwi0TgCd4cre1CwiFastm1Cgn
• premature death_Fas<tm1Cgn>/Fas<tm1Cgn>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0002083B6CgFastm1CgnTgCd4cre1CwiFastm1CgnFastm1CgnTgCd4cre1Cwi0TgCd4cre1CwiFastm1Cgn
• abnormal immune system morphology_Fas<tm1Cgn>/Fas<tm1Cgn>,Tg(Mx1-cre)1Cgn/0
  http://metadb.riken.jp/0000685B6CgFastm1CgnTgMx1cre1CgnFastm1CgnFastm1CgnTgMx1cre1Cgn0TgMx1cre1CgnFastm1Cgn