Mark M W. Chong, et.al., Epigenetic propagation of CD4 expression is established by the Cd4 proximal enhancer in helper T cells., Genes & development, 2010, 24

http://rdf.ncbi.nlm.nih.gov/pubmed/20360383

Mark M W. Chong, et.al., Epigenetic propagation of CD4 expression is established by the Cd4 proximal enhancer in helper T cells., Genes & development, 2010, 24

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD01594
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD01594

allele

http://purl.org/net/cito/citesAsAuthority

• Cd4<tm4.1Litt>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4452055
• Cd4<tm3.2Litt>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4452053
• Cd4<tm3.1Litt>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4452050

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased CD8-positive, alpha-beta T cell number_Cbfb<tm1Itan>/Cbfb<tm1Itan>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008079I129P2OlaHsdC57BL6DBA2Cbfbtm1ItanCbfbtm1ItanTgCd4cre1Cwi0TgCd4cre1CwiCbfbtm1Itan
• abnormal CD8-positive, alpha beta T cell morphology_Cbfb<tm1Itan>/Cbfb<tm1Itan>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0005010I129P2OlaHsdC57BL6DBA2Cbfbtm1ItanCbfbtm1ItanTgCd4cre1Cwi0TgCd4cre1CwiCbfbtm1Itan
• abnormal T cell subpopulation ratio_Cd4<tm3.2Litt>/Cd4<tm3.2Litt>
  http://metadb.riken.jp/0003944I129P2OlaHsdFVBNCd4tm32LittCd4tm32LittCd4tm32Litt
• abnormal CD4-positive, alpha beta T cell morphology_Cd4<tm3.2Litt>/Cd4<tm3.2Litt>
  http://metadb.riken.jp/0002432I129P2OlaHsdFVBNCd4tm32LittCd4tm32LittCd4tm32Litt
• abnormal T cell subpopulation ratio_Cd4<tm3.2Litt>/Cd4<tm3.2Litt>,H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>
  http://metadb.riken.jp/0003944I129P2OlaHsd129S2SvPasFVBNCd4tm32LittCd4tm32LittH2Ab1tm1GruH2Ab1tm1GruH2Ab1tm1GruCd4tm32Litt
• abnormal T cell differentiation_Cd4<tm3.1Litt>/Cd4<tm4.1Litt>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0002145I129P2OlaHsd129S4SvJaeSorFVBNCd4tm31LittCd4tm41LittTgCd4cre1Cwi0Cd4tm41LittCd4tm31LittTgCd4cre1Cwi
• decreased double-positive T cell number_Cd4<tm3.1Litt>/Cd4<tm3.1Litt>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0005092I129P2OlaHsdC57BL6DBA2FVBNCd4tm31LittCd4tm31LittTgCd4cre1Cwi0TgCd4cre1CwiCd4tm31Litt
• abnormal T cell subpopulation ratio_Cd4<tm3.1Litt>/Cd4<tm3.1Litt>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0003944I129P2OlaHsdC57BL6DBA2FVBNCd4tm31LittCd4tm31LittTgCd4cre1Cwi0TgCd4cre1CwiCd4tm31Litt
• increased CD8-positive, alpha-beta T cell number_Cd4<tm3.2Litt>/Cd4<tm3.2Litt>,H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>
  http://metadb.riken.jp/0008078I129P2OlaHsd129S2SvPasFVBNCd4tm32LittCd4tm32LittH2Ab1tm1GruH2Ab1tm1GruH2Ab1tm1GruCd4tm32Litt
• abnormal T cell differentiation_Cd4<tm3.1Litt>/Cd4<tm3.1Litt>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0002145I129P2OlaHsdC57BL6DBA2FVBNCd4tm31LittCd4tm31LittTgCd4cre1Cwi0TgCd4cre1CwiCd4tm31Litt
• increased CD8-positive, alpha-beta T cell number_Cd4<tm1Litt>/Cd4<tm1Litt>
  http://metadb.riken.jp/0008078I129S2SvPasCd4tm1LittCd4tm1LittCd4tm1Litt
• abnormal double-positive T cell morphology_Cd4<tm3.2Litt>/Cd4<tm3.2Litt>
  http://metadb.riken.jp/0002408I129P2OlaHsdFVBNCd4tm32LittCd4tm32LittCd4tm32Litt
• decreased CD4-positive, alpha beta T cell number_B2m<tm1Jae>/B2m<tm1Jae>,Cd4<tm3.2Litt>/Cd4<tm3.2Litt>
  http://metadb.riken.jp/0008075I129P2OlaHsd129S2SvPasFVBNB2mtm1JaeB2mtm1JaeCd4tm32LittCd4tm32LittCd4tm32LittB2mtm1Jae
• abnormal T cell subpopulation ratio_Cd4<tm3.2Litt>/Cd4<tm4.1Litt>
  http://metadb.riken.jp/0003944I129P2OlaHsd129S4SvJaeSorFVBNCd4tm32LittCd4tm41LittCd4tm41LittCd4tm32Litt
• increased double-positive T cell number_Cbfb<tm1Itan>/Cbfb<tm1Itan>,Cd4<tm3.1Litt>/Cd4<tm3.1Litt>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0005091I129P2OlaHsdC57BL6DBA2FVBNCbfbtm1ItanCbfbtm1ItanCd4tm31LittCd4tm31LittTgCd4cre1Cwi0Cd4tm31LittTgCd4cre1CwiCbfbtm1Itan
• decreased CD4-positive, alpha beta T cell number_Cd4<tm3.1Litt>/Cd4<tm3.1Litt>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008075I129P2OlaHsdC57BL6DBA2FVBNCd4tm31LittCd4tm31LittTgCd4cre1Cwi0TgCd4cre1CwiCd4tm31Litt
• abnormal T cell subpopulation ratio_Cbfb<tm1Itan>/Cbfb<tm1Itan>,Cd4<tm3.1Litt>/Cd4<tm3.1Litt>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0003944I129P2OlaHsdC57BL6DBA2FVBNCbfbtm1ItanCbfbtm1ItanCd4tm31LittCd4tm31LittTgCd4cre1Cwi0Cd4tm31LittTgCd4cre1CwiCbfbtm1Itan
• abnormal T cell differentiation_Cd4<tm3.2Litt>/Cd4<tm4.1Litt>
  http://metadb.riken.jp/0002145I129P2OlaHsd129S4SvJaeSorFVBNCd4tm32LittCd4tm41LittCd4tm41LittCd4tm32Litt
• decreased double-positive T cell number_Cbfb<tm1Itan>/Cbfb<tm1Itan>,Cd4<tm3.1Litt>/Cd4<tm3.1Litt>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0005092I129P2OlaHsdC57BL6DBA2FVBNCbfbtm1ItanCbfbtm1ItanCd4tm31LittCd4tm31LittTgCd4cre1Cwi0Cd4tm31LittTgCd4cre1CwiCbfbtm1Itan
• abnormal T cell differentiation_B2m<tm1Jae>/B2m<tm1Jae>,Cd4<tm3.2Litt>/Cd4<tm3.2Litt>
  http://metadb.riken.jp/0002145I129P2OlaHsd129S2SvPasFVBNB2mtm1JaeB2mtm1JaeCd4tm32LittCd4tm32LittCd4tm32LittB2mtm1Jae
• decreased CD4-positive, alpha beta T cell number_Cbfb<tm1Itan>/Cbfb<tm1Itan>,Cd4<tm3.1Litt>/Cd4<tm3.1Litt>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008075I129P2OlaHsdC57BL6DBA2FVBNCbfbtm1ItanCbfbtm1ItanCd4tm31LittCd4tm31LittTgCd4cre1Cwi0Cd4tm31LittTgCd4cre1CwiCbfbtm1Itan
• increased CD8-positive, alpha-beta T cell number_Cd4<tm3.1Litt>/Cd4<tm3.1Litt>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008078I129P2OlaHsdC57BL6DBA2FVBNCd4tm31LittCd4tm31LittTgCd4cre1Cwi0TgCd4cre1CwiCd4tm31Litt
• increased T cell proliferation_B2m<tm1Jae>/B2m<tm1Jae>,Cd4<tm3.2Litt>/Cd4<tm3.2Litt>
  http://metadb.riken.jp/0005348I129P2OlaHsd129S2SvPasFVBNB2mtm1JaeB2mtm1JaeCd4tm32LittCd4tm32LittCd4tm32LittB2mtm1Jae
• abnormal T cell differentiation_Cd4<tm3.2Litt>/Cd4<tm3.2Litt>
  http://metadb.riken.jp/0002145I129P2OlaHsdFVBNCd4tm32LittCd4tm32LittCd4tm32Litt
• abnormal T cell subpopulation ratio_B2m<tm1Jae>/B2m<tm1Jae>,Cd4<tm3.2Litt>/Cd4<tm3.2Litt>
  http://metadb.riken.jp/0003944I129P2OlaHsd129S2SvPasFVBNB2mtm1JaeB2mtm1JaeCd4tm32LittCd4tm32LittCd4tm32LittB2mtm1Jae
• decreased CD4-positive, alpha beta T cell number_Cd4<tm3.2Litt>/Cd4<tm4.1Litt>
  http://metadb.riken.jp/0008075I129P2OlaHsd129S4SvJaeSorFVBNCd4tm32LittCd4tm41LittCd4tm41LittCd4tm32Litt
• abnormal T cell subpopulation ratio_Cd4<tm3.1Litt>/Cd4<tm4.1Litt>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0003944I129P2OlaHsd129S4SvJaeSorFVBNCd4tm31LittCd4tm41LittTgCd4cre1Cwi0Cd4tm41LittCd4tm31LittTgCd4cre1Cwi
• abnormal double-positive T cell morphology_Cbfb<tm1Itan>/Cbfb<tm1Itan>,Cd4<tm3.1Litt>/Cd4<tm3.1Litt>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0002408I129P2OlaHsdC57BL6DBA2FVBNCbfbtm1ItanCbfbtm1ItanCd4tm31LittCd4tm31LittTgCd4cre1Cwi0Cd4tm31LittTgCd4cre1CwiCbfbtm1Itan
• decreased CD4-positive, alpha beta T cell number_Cd4<tm1Litt>/Cd4<tm1Litt>
  http://metadb.riken.jp/0008075I129S2SvPasCd4tm1LittCd4tm1LittCd4tm1Litt
• increased CD8-positive, alpha-beta T cell number_Cbfb<tm1Itan>/Cbfb<tm1Itan>,Cd4<tm3.1Litt>/Cd4<tm3.1Litt>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008078I129P2OlaHsdC57BL6DBA2FVBNCbfbtm1ItanCbfbtm1ItanCd4tm31LittCd4tm31LittTgCd4cre1Cwi0Cd4tm31LittTgCd4cre1CwiCbfbtm1Itan
• increased CD8-positive, alpha-beta T cell number_B2m<tm1Jae>/B2m<tm1Jae>,Cd4<tm3.2Litt>/Cd4<tm3.2Litt>
  http://metadb.riken.jp/0008078I129P2OlaHsd129S2SvPasFVBNB2mtm1JaeB2mtm1JaeCd4tm32LittCd4tm32LittCd4tm32LittB2mtm1Jae
• increased CD8-positive, alpha-beta T cell number_Cd4<tm3.2Litt>/Cd4<tm4.1Litt>
  http://metadb.riken.jp/0008078I129P2OlaHsd129S4SvJaeSorFVBNCd4tm32LittCd4tm41LittCd4tm41LittCd4tm32Litt
• increased CD8-positive, alpha-beta T cell number_Cd4<tm3.2Litt>/Cd4<tm3.2Litt>
  http://metadb.riken.jp/0008078I129P2OlaHsdFVBNCd4tm32LittCd4tm32LittCd4tm32Litt
• increased double-positive T cell number_Cbfb<tm1Itan>/Cbfb<tm1Itan>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0005091I129P2OlaHsdC57BL6DBA2Cbfbtm1ItanCbfbtm1ItanTgCd4cre1Cwi0TgCd4cre1CwiCbfbtm1Itan
• decreased CD4-positive, alpha beta T cell number_Cd4<tm3.1Litt>/Cd4<tm4.1Litt>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008075I129P2OlaHsd129S4SvJaeSorFVBNCd4tm31LittCd4tm41LittTgCd4cre1Cwi0Cd4tm41LittCd4tm31LittTgCd4cre1Cwi
• decreased double-positive T cell number_Cd4<tm3.2Litt>/Cd4<tm3.2Litt>
  http://metadb.riken.jp/0005092I129P2OlaHsdFVBNCd4tm32LittCd4tm32LittCd4tm32Litt
• decreased CD4-positive, alpha beta T cell number_Cd4<tm3.2Litt>/Cd4<tm3.2Litt>,H2-Ab1<tm1Gru>/H2-Ab1<tm1Gru>
  http://metadb.riken.jp/0008075I129P2OlaHsd129S2SvPasFVBNCd4tm32LittCd4tm32LittH2Ab1tm1GruH2Ab1tm1GruH2Ab1tm1GruCd4tm32Litt
• increased CD8-positive, alpha-beta T cell number_Cd4<tm3.1Litt>/Cd4<tm4.1Litt>,Tg(Cd4-cre)1Cwi/0
  http://metadb.riken.jp/0008078I129P2OlaHsd129S4SvJaeSorFVBNCd4tm31LittCd4tm41LittTgCd4cre1Cwi0Cd4tm41LittCd4tm31LittTgCd4cre1Cwi
• decreased CD4-positive, alpha beta T cell number_Cd4<tm3.2Litt>/Cd4<tm3.2Litt>
  http://metadb.riken.jp/0008075I129P2OlaHsdFVBNCd4tm32LittCd4tm32LittCd4tm32Litt