Zhaozhu. Qiu, et.al., Abl family tyrosine kinases are essential for basement membrane integrity and cortical lamination in the cerebellum., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, 30

http://rdf.ncbi.nlm.nih.gov/pubmed/20980600

Zhaozhu. Qiu, et.al., Abl family tyrosine kinases are essential for basement membrane integrity and cortical lamination in the cerebellum., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, 30

http://rdf.ncbi.nlm.nih.gov/pubmed/

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD03310
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03310
• CD12549
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD12549
• CD02710
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD02710
• CD12601
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD12601
• CD33353
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD33353
• CD14146
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD14146
• CD39199
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD39199
• CD03217
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03217

allele

http://purl.org/net/cito/citesAsAuthority

• Abl1<tm2.1Goff>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4850040
• Abl1<tm2.2Goff>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4850041

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• absent cerebellar lobules_Abl1<tm2.1Goff>/Abl1<tm2.1Goff>,Abl2<tm1Ajk>/Abl2<tm1Ajk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0006098I129C57BL6C57BL6JSJLAbl1tm21GoffAbl1tm21GoffAbl2tm1AjkAbl2tm1AjkTgNescre1Kln0Abl2tm1AjkAbl1tm21GoffTgNescre1Kln
• abnormal cerebellar layer morphology_Abl1<tm2.1Goff>/Abl1<tm2.1Goff>,Abl2<tm1Ajk>/Abl2<tm1Ajk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0009956I129C57BL6C57BL6JSJLAbl1tm21GoffAbl1tm21GoffAbl2tm1AjkAbl2tm1AjkTgNescre1Kln0Abl2tm1AjkAbl1tm21GoffTgNescre1Kln
• small cerebellum_Abl1<tm2.1Goff>/Abl1<tm2.1Goff>,Abl2<tm1Ajk>/Abl2<tm1Ajk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000852I129C57BL6C57BL6JSJLAbl1tm21GoffAbl1tm21GoffAbl2tm1AjkAbl2tm1AjkTgNescre1Kln0Abl2tm1AjkAbl1tm21GoffTgNescre1Kln
• abnormal brain morphology_Abl1<tm2.1Goff>/Abl1<tm2.1Goff>,Abl2<tm1Ajk>/Abl2<tm1Ajk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002152I129C57BL6C57BL6JSJLAbl1tm21GoffAbl1tm21GoffAbl2tm1AjkAbl2tm1AjkTgNescre1Kln0Abl2tm1AjkAbl1tm21GoffTgNescre1Kln
• thymus atrophy_Abl1<tm2.2Goff>/Abl1<tm2.2Goff>
  http://metadb.riken.jp/0003644I129P2OlaHsdC57BL6JFVBNAbl1tm22GoffAbl1tm22GoffAbl1tm22Goff
• decreased cerebellar granule cell precursor proliferation_Abl1<tm2.1Goff>/Abl1<tm2.1Goff>,Abl2<tm1Ajk>/Abl2<tm1Ajk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0013551I129C57BL6C57BL6JSJLAbl1tm21GoffAbl1tm21GoffAbl2tm1AjkAbl2tm1AjkTgNescre1Kln0Abl2tm1AjkAbl1tm21GoffTgNescre1Kln
• ectopic cerebellar granule cells_Abl1<tm2.2Goff>/Abl1<tm2.2Goff>
  http://metadb.riken.jp/0002762I129P2OlaHsdC57BL6JFVBNAbl1tm22GoffAbl1tm22GoffAbl1tm22Goff
• spleen atrophy_Abl1<tm2.2Goff>/Abl1<tm2.2Goff>
  http://metadb.riken.jp/0003643I129P2OlaHsdC57BL6JFVBNAbl1tm22GoffAbl1tm22GoffAbl1tm22Goff
• ectopic cerebellar granule cells_Abl1<tm2.1Goff>/Abl1<tm2.1Goff>,Abl2<tm1Ajk>/Abl2<tm1Ajk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002762I129C57BL6C57BL6JSJLAbl1tm21GoffAbl1tm21GoffAbl2tm1AjkAbl2tm1AjkTgNescre1Kln0Abl2tm1AjkAbl1tm21GoffTgNescre1Kln
• abnormal cerebellum fissure morphology_Abl1<tm2.1Goff>/Abl1<tm2.1Goff>,Abl2<tm1Ajk>/Abl2<tm1Ajk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0009267I129C57BL6C57BL6JSJLAbl1tm21GoffAbl1tm21GoffAbl2tm1AjkAbl2tm1AjkTgNescre1Kln0Abl2tm1AjkAbl1tm21GoffTgNescre1Kln
• abnormal cerebellum morphology_Abl1<tm2.1Goff>/Abl1<tm2.1Goff>,Abl2<tm1Ajk>/Abl2<tm1Ajk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000849I129C57BL6C57BL6JSJLAbl1tm21GoffAbl1tm21GoffAbl2tm1AjkAbl2tm1AjkTgNescre1Kln0Abl2tm1AjkAbl1tm21GoffTgNescre1Kln
• abnormal cerebellum white matter morphology_Abl1<tm2.1Goff>/Abl1<tm2.1Goff>,Abl2<tm1Ajk>/Abl2<tm1Ajk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0009978I129C57BL6C57BL6JSJLAbl1tm21GoffAbl1tm21GoffAbl2tm1AjkAbl2tm1AjkTgNescre1Kln0Abl2tm1AjkAbl1tm21GoffTgNescre1Kln
• reduced cerebellar foliation_Abl1<tm2.1Goff>/Abl1<tm2.1Goff>,Abl2<tm1Ajk>/Abl2<tm1Ajk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0009719I129C57BL6C57BL6JSJLAbl1tm21GoffAbl1tm21GoffAbl2tm1AjkAbl2tm1AjkTgNescre1Kln0Abl2tm1AjkAbl1tm21GoffTgNescre1Kln
• decreased body size_Abl1<tm2.2Goff>/Abl1<tm2.2Goff>
  http://metadb.riken.jp/0001265I129P2OlaHsdC57BL6JFVBNAbl1tm22GoffAbl1tm22GoffAbl1tm22Goff
• ectopic Purkinje cell_Abl1<tm2.1Goff>/Abl1<tm2.1Goff>,Abl2<tm1Ajk>/Abl2<tm1Ajk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0000885I129C57BL6C57BL6JSJLAbl1tm21GoffAbl1tm21GoffAbl2tm1AjkAbl2tm1AjkTgNescre1Kln0Abl2tm1AjkAbl1tm21GoffTgNescre1Kln
• abnormal cerebellar lobule formation_Abl1<tm2.1Goff>/Abl1<tm2.1Goff>,Abl2<tm1Ajk>/Abl2<tm1Ajk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0006097I129C57BL6C57BL6JSJLAbl1tm21GoffAbl1tm21GoffAbl2tm1AjkAbl2tm1AjkTgNescre1Kln0Abl2tm1AjkAbl1tm21GoffTgNescre1Kln
• neonatal lethality, incomplete penetrance_Abl1<tm2.2Goff>/Abl1<tm2.2Goff>
  http://metadb.riken.jp/0011088I129P2OlaHsdC57BL6JFVBNAbl1tm22GoffAbl1tm22GoffAbl1tm22Goff
• abnormal cerebellum development_Abl1<tm2.2Goff>/Abl1<tm2.2Goff>
  http://metadb.riken.jp/0000854I129P2OlaHsdC57BL6JFVBNAbl1tm22GoffAbl1tm22GoffAbl1tm22Goff
• absent cerebellum fissure_Abl1<tm2.1Goff>/Abl1<tm2.1Goff>,Abl2<tm1Ajk>/Abl2<tm1Ajk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0009268I129C57BL6C57BL6JSJLAbl1tm21GoffAbl1tm21GoffAbl2tm1AjkAbl2tm1AjkTgNescre1Kln0Abl2tm1AjkAbl1tm21GoffTgNescre1Kln
• postnatal lethality, incomplete penetrance_Abl1<tm2.1Goff>/Abl1<tm2.1Goff>,Abl2<tm1Ajk>/Abl2<tm1Ajk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0011086I129C57BL6C57BL6JSJLAbl1tm21GoffAbl1tm21GoffAbl2tm1AjkAbl2tm1AjkTgNescre1Kln0Abl2tm1AjkAbl1tm21GoffTgNescre1Kln
• impaired coordination_Abl1<tm2.1Goff>/Abl1<tm2.1Goff>,Abl2<tm1Ajk>/Abl2<tm1Ajk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0001405I129C57BL6C57BL6JSJLAbl1tm21GoffAbl1tm21GoffAbl2tm1AjkAbl2tm1AjkTgNescre1Kln0Abl2tm1AjkAbl1tm21GoffTgNescre1Kln
• ectopic Bergmann glia cells_Abl1<tm2.1Goff>/Abl1<tm2.1Goff>,Abl2<tm1Ajk>/Abl2<tm1Ajk>,Tg(Nes-cre)1Kln/0
  http://metadb.riken.jp/0002763I129C57BL6C57BL6JSJLAbl1tm21GoffAbl1tm21GoffAbl2tm1AjkAbl2tm1AjkTgNescre1Kln0Abl2tm1AjkAbl1tm21GoffTgNescre1Kln
• abnormal cerebellar foliation_Abl1<tm2.2Goff>/Abl1<tm2.2Goff>
  http://metadb.riken.jp/0000857I129P2OlaHsdC57BL6JFVBNAbl1tm22GoffAbl1tm22GoffAbl1tm22Goff