increased sarcoma incidence_Trp53<tm1Tyj>/Trp53<tm1Tyj>

http://metadb.riken.jp/0002032I129S2SvPasC57BL6Trp53tm1TyjTrp53tm1TyjTrp53tm1Tyj

increased sarcoma incidence_Trp53<tm1Tyj>/Trp53<tm1Tyj>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trp53<tm1Tyj>/Trp53<tm1Tyj>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Tyj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased sarcoma incidence
  http://purl.obolibrary.org/obo/MP_0002032

文献

http://purl.org/net/cito/citesAsAuthority

• J. Lawler, et.al., Thrombospondin-1 gene expression affects survival and tumor spectrum of p53-deficient mice., The American journal of pathology, 2001, 159
  http://rdf.ncbi.nlm.nih.gov/pubmed/11696456
• T. Jacks, et.al., Tumor spectrum analysis in p53-mutant mice., Current biology : CB, 1994, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/7922305
• Gene A. Lang, et.al., Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome., Cell, 2004, 119
  http://rdf.ncbi.nlm.nih.gov/pubmed/15607981