tau protein deposits_Tg(Prnp-MAPT*P301S)PS19Vle/0

http://metadb.riken.jp/0004250IC3HC57BL6TgPrnpMAPTP301SPS19Vle0TgPrnpMAPTP301SPS19Vle

tau protein deposits_Tg(Prnp-MAPT*P301S)PS19Vle/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion PS19, Virginia M Y Lee
  http://metadb.riken.jp/db/mgi_rdf/MGI:3768406

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Prnp-MAPT*P301S)PS19Vle/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Prnp-MAPT*P301S)PS19Vle

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C3H * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• tau protein deposits
  http://purl.obolibrary.org/obo/MP_0004250

文献

http://purl.org/net/cito/citesAsAuthority

• Yasumasa. Yoshiyama, et.al., Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model., Neuron, 2007, 53
  http://rdf.ncbi.nlm.nih.gov/pubmed/17270732
• David E. Hurtado, et.al., A{beta} accelerates the spatiotemporal progression of tau pathology and augments tau amyloidosis in an Alzheimer mouse model., The American journal of pathology, 2010, 177
  http://rdf.ncbi.nlm.nih.gov/pubmed/20802182
• Sumihiro. Maeda, et.al., Expression of A152T human tau causes age-dependent neuronal dysfunction and loss in transgenic mice., EMBO reports, 2016, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/26931567