embryonic lethality, complete penetrance_Casp8<tm1.1Raz>/Casp8<tm1.1Raz>

http://metadb.riken.jp/0011092I129P2OlaHsdCasp8tm11RazCasp8tm11RazCasp8tm11Raz

embryonic lethality, complete penetrance_Casp8<tm1.1Raz>/Casp8<tm1.1Raz>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• caspase 8
  http://metadb.riken.jp/db/mgi_rdf/MGI:1261423

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Casp8<tm1.1Raz>/Casp8<tm1.1Raz>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Casp8<tm1.1Raz>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality
  http://purl.obolibrary.org/obo/MP_0011092

文献

http://purl.org/net/cito/citesAsAuthority

• William J. Kaiser, et.al., RIP3 mediates the embryonic lethality of caspase-8-deficient mice., Nature, 2011, 471
  http://rdf.ncbi.nlm.nih.gov/pubmed/21368762
• Leonardo. Salmena, et.al., Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity., Genes & development, 2003, 17
  http://rdf.ncbi.nlm.nih.gov/pubmed/12654726