Leonardo. Salmena, et.al., Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity., Genes & development, 2003, 17

http://rdf.ncbi.nlm.nih.gov/pubmed/12654726

Leonardo. Salmena, et.al., Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity., Genes & development, 2003, 17

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Casp8<tm1Raz>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2655730
• Casp8<tm1.1Raz>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5546196

class

http://purl.org/net/cito/citesAsAuthority

• Casp8<tm1Raz>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2655730
• Casp8<tm1.1Raz>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5546196

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• embryonic lethality, complete penetrance_Casp8<tm1.1Raz>/Casp8<tm1.1Raz>
  http://metadb.riken.jp/0011092I129P2OlaHsdCasp8tm11RazCasp8tm11RazCasp8tm11Raz
• decreased T cell apoptosis_Casp8<tm1Raz>/Casp8<tm1Raz>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0006414I129P2OlaHsdC57BL6CBACasp8tm1RazCasp8tm1RazTgLckcre548Jxm0Casp8tm1RazTgLckcre548Jxm
• abnormal CD8-positive, alpha-beta T cell physiology_Casp8<tm1Raz>/Casp8<tm1Raz>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0004392I129P2OlaHsdC57BL6CBACasp8tm1RazCasp8tm1RazTgLckcre548Jxm0Casp8tm1RazTgLckcre548Jxm
• abnormal T cell morphology_Casp8<tm1Raz>/Casp8<tm1Raz>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0008037I129P2OlaHsdC57BL6CBACasp8tm1RazCasp8tm1RazTgLckcre548Jxm0Casp8tm1RazTgLckcre548Jxm
• decreased CD8-positive, alpha-beta T cell number_Casp8<tm1Raz>/Casp8<tm1Raz>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0008079I129P2OlaHsdC57BL6CBACasp8tm1RazCasp8tm1RazTgLckcre548Jxm0Casp8tm1RazTgLckcre548Jxm
• decreased T cell proliferation_Casp8<tm1Raz>/Casp8<tm1Raz>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0005095I129P2OlaHsdC57BL6CBACasp8tm1RazCasp8tm1RazTgLckcre548Jxm0Casp8tm1RazTgLckcre548Jxm
• decreased CD4-positive, alpha beta T cell number_Casp8<tm1Raz>/Casp8<tm1Raz>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0008075I129P2OlaHsdC57BL6CBACasp8tm1RazCasp8tm1RazTgLckcre548Jxm0Casp8tm1RazTgLckcre548Jxm
• abnormal T cell subpopulation ratio_Casp8<tm1Raz>/Casp8<tm1Raz>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0003944I129P2OlaHsdC57BL6CBACasp8tm1RazCasp8tm1RazTgLckcre548Jxm0Casp8tm1RazTgLckcre548Jxm
• decreased T cell number_Casp8<tm1Raz>/Casp8<tm1Raz>,Tg(Lck-cre)548Jxm/0
  http://metadb.riken.jp/0005018I129P2OlaHsdC57BL6CBACasp8tm1RazCasp8tm1RazTgLckcre548Jxm0Casp8tm1RazTgLckcre548Jxm