Brian T. Fife, et.al., Inhibition of T cell activation and autoimmune diabetes using a B cell surface-linked CTLA-4 agonist., The Journal of clinical investigation, 2006, 116

http://rdf.ncbi.nlm.nih.gov/pubmed/16886063

Brian T. Fife, et.al., Inhibition of T cell activation and autoimmune diabetes using a B cell surface-linked CTLA-4 agonist., The Journal of clinical investigation, 2006, 116

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Ighm-Ctla4Ig/Cd80)1Jbs
  http://metadb.riken.jp/db/mgi_rdf/MGI:3711772

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased susceptibility to autoimmune diabetes_Tg(Ighm-Ctla4Ig/Cd80)1Jbs/0
  http://metadb.riken.jp/0004804NODFVBTgIghmCtla4IgCd801JbsTgIghmCtla4IgCd801Jbs0TgIghmCtla4IgCd801Jbs
• decreased regulatory T cell number_Cd80<tm1Shr>/Cd80<tm1Shr>,Cd86<tm2Shr>/Cd86<tm2Shr>,Tg(Ighm-Ctla4Ig/Cd80)1Jbs/0
  http://metadb.riken.jp/0004974I129S4SvJaeFVBNNODCd80tm1ShrCd80tm1ShrCd86tm2ShrCd86tm2ShrTgIghmCtla4IgCd801Jbs0Cd86tm2ShrCd80tm1ShrTgIghmCtla4IgCd801Jbs
• decreased regulatory T cell number_Cd80<tm1Shr>/Cd80<tm1Shr>,Cd86<tm2Shr>/Cd86<tm2Shr>
  http://metadb.riken.jp/0004974I129S4SvJaeCd80tm1ShrCd80tm1ShrCd86tm2ShrCd86tm2ShrCd80tm1ShrCd86tm2Shr
• decreased susceptibility to autoimmune diabetes_Cd80<tm1Shr>/Cd80<tm1Shr>,Cd86<tm2Shr>/Cd86<tm2Shr>,Tg(Ighm-Ctla4Ig/Cd80)1Jbs/0
  http://metadb.riken.jp/0004804I129S4SvJaeFVBNNODCd80tm1ShrCd80tm1ShrCd86tm2ShrCd86tm2ShrTgIghmCtla4IgCd801Jbs0Cd86tm2ShrCd80tm1ShrTgIghmCtla4IgCd801Jbs
• insulitis_Cd80<tm1Shr>/Cd80<tm1Shr>,Cd86<tm2Shr>/Cd86<tm2Shr>,Tg(Ighm-Ctla4Ig/Cd80)1Jbs/0
  http://metadb.riken.jp/0004031I129S4SvJaeFVBNNODCd80tm1ShrCd80tm1ShrCd86tm2ShrCd86tm2ShrTgIghmCtla4IgCd801Jbs0Cd86tm2ShrCd80tm1ShrTgIghmCtla4IgCd801Jbs
• abnormal B cell physiology_Tg(Ighm-Ctla4Ig/Cd80)1Jbs/0
  http://metadb.riken.jp/0002459IFVBNTgIghmCtla4IgCd801Jbs0TgIghmCtla4IgCd801Jbs
• increased susceptibility to autoimmune diabetes_Cd80<tm1Shr>/Cd80<tm1Shr>,Cd86<tm2Shr>/Cd86<tm2Shr>
  http://metadb.riken.jp/0004803I129S4SvJaeCd80tm1ShrCd80tm1ShrCd86tm2ShrCd86tm2ShrCd80tm1ShrCd86tm2Shr

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Ighm-Ctla4Ig/Cd80)1Jbs
  http://metadb.riken.jp/db/mgi_rdf/MGI:3711772