Erik D. Roberson, et.al., Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model., Science (New York, N.Y.), 2007, 316

http://rdf.ncbi.nlm.nih.gov/pubmed/17478722

Erik D. Roberson, et.al., Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model., Science (New York, N.Y.), 2007, 316

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal long term object recognition memory_Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0002801IC57BL6DBA2TgPDGFBAPPSwInd20Lms0TgPDGFBAPPSwInd20Lms
• premature death_Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0002083IC57BL6DBA2TgPDGFBAPPSwInd20Lms0TgPDGFBAPPSwInd20Lms
• hyperactivity_Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0001399IC57BL6DBA2TgPDGFBAPPSwInd20Lms0TgPDGFBAPPSwInd20Lms
• abnormal neuron differentiation_Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0009937IC57BL6DBA2TgPDGFBAPPSwInd20Lms0TgPDGFBAPPSwInd20Lms
• abnormal spatial learning_Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0001463IC57BL6DBA2TgPDGFBAPPSwInd20Lms0TgPDGFBAPPSwInd20Lms
• abnormal neuron differentiation_Mapt<tm1Hnd>/Mapt<tm1Hnd>,Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0009937I129X1SvJC57BL6DBA2Mapttm1HndMapttm1HndTgPDGFBAPPSwInd20Lms0Mapttm1HndTgPDGFBAPPSwInd20Lms
• abnormal neuron differentiation_Mapt<tm1Hnd>/Mapt<+>,Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0009937I129X1SvJC57BL6DBA2Mapttm1HndMaptTgPDGFBAPPSwInd20Lms0MaptTgPDGFBAPPSwInd20LmsMapttm1Hnd
• decreased susceptibility to pharmacologically induced seizures_Mapt<tm1Hnd>/Mapt<tm1Hnd>
  http://metadb.riken.jp/0002887I129X1SvJC57BL6Mapttm1HndMapttm1HndMapttm1Hnd
• amyloid beta deposits_Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0003329IC57BL6DBA2TgPDGFBAPPSwInd20Lms0TgPDGFBAPPSwInd20Lms
• decreased susceptibility to pharmacologically induced seizures_Mapt<tm1Hnd>/Mapt<+>,Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0002887I129X1SvJC57BL6DBA2Mapttm1HndMaptTgPDGFBAPPSwInd20Lms0MaptTgPDGFBAPPSwInd20LmsMapttm1Hnd
• decreased susceptibility to pharmacologically induced seizures_Mapt<tm1Hnd>/Mapt<tm1Hnd>,Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0002887I129X1SvJC57BL6DBA2Mapttm1HndMapttm1HndTgPDGFBAPPSwInd20Lms0Mapttm1HndTgPDGFBAPPSwInd20Lms
• abnormal neuron morphology_Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0002882IC57BL6DBA2TgPDGFBAPPSwInd20Lms0TgPDGFBAPPSwInd20Lms
• abnormal neuron morphology_Mapt<tm1Hnd>/Mapt<tm1Hnd>,Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0002882I129X1SvJC57BL6DBA2Mapttm1HndMapttm1HndTgPDGFBAPPSwInd20Lms0Mapttm1HndTgPDGFBAPPSwInd20Lms
• increased susceptibility to pharmacologically induced seizures_Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0002906IC57BL6DBA2TgPDGFBAPPSwInd20Lms0TgPDGFBAPPSwInd20Lms
• decreased susceptibility to pharmacologically induced seizures_Mapt<tm1Hnd>/Mapt<+>
  http://metadb.riken.jp/0002887I129X1SvJC57BL6Mapttm1HndMaptMapttm1HndMapt
• amyloid beta deposits_Mapt<tm1Hnd>/Mapt<tm1Hnd>,Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0003329I129X1SvJC57BL6DBA2Mapttm1HndMapttm1HndTgPDGFBAPPSwInd20Lms0Mapttm1HndTgPDGFBAPPSwInd20Lms
• amyloid beta deposits_Mapt<tm1Hnd>/Mapt<+>,Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0003329I129X1SvJC57BL6DBA2Mapttm1HndMaptTgPDGFBAPPSwInd20Lms0MaptTgPDGFBAPPSwInd20LmsMapttm1Hnd
• abnormal spatial learning_Mapt<tm1Hnd>/Mapt<+>,Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0001463I129X1SvJC57BL6DBA2Mapttm1HndMaptTgPDGFBAPPSwInd20Lms0MaptTgPDGFBAPPSwInd20LmsMapttm1Hnd
• abnormal neuron morphology_Mapt<tm1Hnd>/Mapt<+>,Tg(PDGFB-APPSwInd)20Lms/0
  http://metadb.riken.jp/0002882I129X1SvJC57BL6DBA2Mapttm1HndMaptTgPDGFBAPPSwInd20Lms0MaptTgPDGFBAPPSwInd20LmsMapttm1Hnd