Luis C. Fernandez-Diaz, et.al., The absence of Prep1 causes p53-dependent apoptosis of mouse pluripotent epiblast cells., Development (Cambridge, England), 2010, 137

http://rdf.ncbi.nlm.nih.gov/pubmed/20826531

Luis C. Fernandez-Diaz, et.al., The absence of Prep1 causes p53-dependent apoptosis of mouse pluripotent epiblast cells., Development (Cambridge, England), 2010, 137

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Pknox1<tm1Fbla>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4839363

class

http://purl.org/net/cito/citesAsAuthority

• Pknox1<tm1Fbla>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4839363

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal embryonic tissue morphology_Pknox1<tm1Fbla>/Pknox1<tm1Fbla>
  http://metadb.riken.jp/0002085B6CgPknox1tm1FblaPknox1tm1FblaPknox1tm1FblaPknox1tm1Fbla
• abnormal pluripotent precursor cell morphology_Pknox1<tm1Fbla>/Pknox1<tm1Fbla>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0002399I129S2SvPasC57BL6Pknox1tm1FblaPknox1tm1FblaTrp53tm1TyjTrp53tm1TyjPknox1tm1FblaTrp53tm1Tyj
• absent anterior visceral endoderm_Pknox1<tm1Fbla>/Pknox1<tm1Fbla>
  http://metadb.riken.jp/0012159B6CgPknox1tm1FblaPknox1tm1FblaPknox1tm1FblaPknox1tm1Fbla
• abnormal extraembryonic endoderm formation_Pknox1<tm1Fbla>/Pknox1<tm1Fbla>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0001724I129S2SvPasC57BL6Pknox1tm1FblaPknox1tm1FblaTrp53tm1TyjTrp53tm1TyjPknox1tm1FblaTrp53tm1Tyj
• abnormal extraembryonic tissue morphology_Pknox1<tm1Fbla>/Pknox1<tm1Fbla>
  http://metadb.riken.jp/0002086B6CgPknox1tm1FblaPknox1tm1FblaPknox1tm1FblaPknox1tm1Fbla
• abnormal visceral endoderm morphology_Pknox1<tm1Fbla>/Pknox1<tm1Fbla>
  http://metadb.riken.jp/0011186B6CgPknox1tm1FblaPknox1tm1FblaPknox1tm1FblaPknox1tm1Fbla
• abnormal embryo development_Pknox1<tm1Fbla>/Pknox1<tm1Fbla>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0001672I129S2SvPasC57BL6Pknox1tm1FblaPknox1tm1FblaTrp53tm1TyjTrp53tm1TyjPknox1tm1FblaTrp53tm1Tyj
• absent mesoderm_Pknox1<tm1Fbla>/Pknox1<tm1Fbla>
  http://metadb.riken.jp/0001683B6CgPknox1tm1FblaPknox1tm1FblaPknox1tm1FblaPknox1tm1Fbla
• abnormal embryonic epiblast morphology_Pknox1<tm1Fbla>/Pknox1<tm1Fbla>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0003886I129S2SvPasC57BL6Pknox1tm1FblaPknox1tm1FblaTrp53tm1TyjTrp53tm1TyjPknox1tm1FblaTrp53tm1Tyj
• abnormal pluripotent precursor cell morphology_Pknox1<tm1Fbla>/Pknox1<tm1Fbla>
  http://metadb.riken.jp/0002399B6CgPknox1tm1FblaPknox1tm1FblaPknox1tm1FblaPknox1tm1Fbla
• failure of primitive streak formation_Pknox1<tm1Fbla>/Pknox1<tm1Fbla>
  http://metadb.riken.jp/0001693B6CgPknox1tm1FblaPknox1tm1FblaPknox1tm1FblaPknox1tm1Fbla
• embryonic lethality, complete penetrance_Pknox1<tm1Fbla>/Pknox1<tm1Fbla>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0011092I129S2SvPasC57BL6Pknox1tm1FblaPknox1tm1FblaTrp53tm1TyjTrp53tm1TyjPknox1tm1FblaTrp53tm1Tyj
• abnormal pluripotent precursor cell morphology_Atm<tm1Fwa>/Atm<tm1Fwa>,Pknox1<tm1Fbla>/Pknox1<tm1Fbla>
  http://metadb.riken.jp/0002399I129S4SvJaeC57BL6Atmtm1FwaAtmtm1FwaPknox1tm1FblaPknox1tm1FblaAtmtm1FwaPknox1tm1Fbla
• embryonic growth retardation_Pknox1<tm1Fbla>/Pknox1<tm1Fbla>
  http://metadb.riken.jp/0003984B6CgPknox1tm1FblaPknox1tm1FblaPknox1tm1FblaPknox1tm1Fbla
• abnormal pluripotent precursor cell morphology_Cdkn2a<tm1.1Brn>/Cdkn2a<tm1.1Brn>,Pknox1<tm1Fbla>/Pknox1<tm1Fbla>
  http://metadb.riken.jp/0002399I129Sv129P2OlaHsdC57BL6Cdkn2atm11BrnCdkn2atm11BrnPknox1tm1FblaPknox1tm1FblaCdkn2atm11BrnPknox1tm1Fbla
• embryonic growth retardation_Atm<tm1Fwa>/Atm<tm1Fwa>,Pknox1<tm1Fbla>/Pknox1<tm1Fbla>
  http://metadb.riken.jp/0003984I129S4SvJaeC57BL6Atmtm1FwaAtmtm1FwaPknox1tm1FblaPknox1tm1FblaAtmtm1FwaPknox1tm1Fbla
• embryonic growth retardation_Pknox1<tm1Fbla>/Pknox1<tm1Fbla>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0003984I129S2SvPasC57BL6Pknox1tm1FblaPknox1tm1FblaTrp53tm1TyjTrp53tm1TyjPknox1tm1FblaTrp53tm1Tyj
• decreased embryo size_Pknox1<tm1Fbla>/Pknox1<tm1Fbla>
  http://metadb.riken.jp/0001698B6CgPknox1tm1FblaPknox1tm1FblaPknox1tm1FblaPknox1tm1Fbla
• embryonic lethality between implantation and somite formation, complete penetrance_Pknox1<tm1Fbla>/Pknox1<tm1Fbla>
  http://metadb.riken.jp/0011096B6CgPknox1tm1FblaPknox1tm1FblaPknox1tm1FblaPknox1tm1Fbla
• preweaning lethality, complete penetrance_Cdkn2a<tm1.1Brn>/Cdkn2a<tm1.1Brn>,Pknox1<tm1Fbla>/Pknox1<tm1Fbla>,Trp53<tm1Tyj>/Trp53<tm1Tyj>
  http://metadb.riken.jp/0011100I129Sv129P2OlaHsd129S2SvPasC57BL6Cdkn2atm11BrnCdkn2atm11BrnPknox1tm1FblaPknox1tm1FblaTrp53tm1TyjTrp53tm1TyjTrp53tm1TyjPknox1tm1FblaCdkn2atm11Brn
• embryonic lethality between implantation and somite formation, incomplete penetrance_Atm<tm1Fwa>/Atm<tm1Fwa>,Pknox1<tm1Fbla>/Pknox1<tm1Fbla>
  http://metadb.riken.jp/0011106I129S4SvJaeC57BL6Atmtm1FwaAtmtm1FwaPknox1tm1FblaPknox1tm1FblaAtmtm1FwaPknox1tm1Fbla
• embryonic growth retardation_Atm<tm1Fwa>/Atm<tm1Fwa>,Pknox1<tm1Fbla>/Pknox1<+>
  http://metadb.riken.jp/0003984I129S4SvJaeC57BL6Atmtm1FwaAtmtm1FwaPknox1tm1FblaPknox1Pknox1tm1FblaPknox1Atmtm1Fwa

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD29092
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD29092
• CD04230
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD04230
• CD01670
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD01670
• CD10711
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD10711
• CD27748
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD27748
• CD10367
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD10367
• CD00958
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD00958
• CD40479
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD40479
• CD20066
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD20066