Jared J. Barrott, et.al., Deletion of mouse Porcn blocks Wnt ligand secretion and reveals an ectodermal etiology of human focal dermal hypoplasia/Goltz syndrome., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108

http://rdf.ncbi.nlm.nih.gov/pubmed/21768372

Jared J. Barrott, et.al., Deletion of mouse Porcn blocks Wnt ligand secretion and reveals an ectodermal etiology of human focal dermal hypoplasia/Goltz syndrome., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Porcn<tm1.1Lcm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4429133

class

http://purl.org/net/cito/citesAsAuthority

• Porcn<tm1.1Lcm>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4429133

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• lethality throughout fetal growth and development, complete penetrance_Porcn<tm1.1Lcm>/Y,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0011099I129S1Sv129X1SvJC57BL6CBAPorcntm11LcmYTgSox2cre1Amc0Porcntm11LcmTgSox2cre1Amc
• decreased body size_Porcn<tm1.1Lcm>/Porcn<+>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0001265I129S1Sv129X1SvJC57BL6CBAPorcntm11LcmPorcnTgSox2cre1Amc0Porcntm11LcmPorcnTgSox2cre1Amc
• abnormal hair follicle development_Porcn<tm1.1Lcm>/Porcn<+>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0003704I129S1Sv129X1SvJC57BL6CBAPorcntm11LcmPorcnTgSox2cre1Amc0Porcntm11LcmPorcnTgSox2cre1Amc
• short tail_Porcn<tm1.1Lcm>/Porcn<+>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0000592I129S1Sv129X1SvJC57BL6CBAPorcntm11LcmPorcnTgSox2cre1Amc0Porcntm11LcmPorcnTgSox2cre1Amc
• abnormal autopod morphology_Porcn<tm1.1Lcm>/Porcn<+>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0000572I129S1Sv129X1SvJC57BL6CBAPorcntm11LcmPorcnTgSox2cre1Amc0Porcntm11LcmPorcnTgSox2cre1Amc
• oligodactyly_Porcn<tm1.1Lcm>/Y,Tg(Prrx1-cre)1Cjt/0
  http://metadb.riken.jp/0000565I129S1Sv129X1SvJC57BL6SJLJPorcntm11LcmYTgPrrx1cre1Cjt0Porcntm11LcmTgPrrx1cre1Cjt
• hairless_Porcn<tm1.1Lcm>/Porcn<+>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0003815I129S1Sv129X1SvJC57BL6CBAPorcntm11LcmPorcnTgSox2cre1Amc0Porcntm11LcmPorcnTgSox2cre1Amc
• abnormal skin morphology_Porcn<tm1.1Lcm>/Y,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0002060I129S1Sv129X1SvJC57BL6Porcntm11LcmYTgMsx2cre5Rem0Porcntm11LcmTgMsx2cre5Rem
• perinatal lethality, complete penetrance_Porcn<tm1.1Lcm>/Porcn<+>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0011089I129S1Sv129X1SvJC57BL6CBAPorcntm11LcmPorcnTgSox2cre1Amc0Porcntm11LcmPorcnTgSox2cre1Amc
• syndactyly_Porcn<tm1.1Lcm>/Y,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0000564I129S1Sv129X1SvJC57BL6Porcntm11LcmYTgMsx2cre5Rem0Porcntm11LcmTgMsx2cre5Rem
• sternum hypoplasia_Porcn<tm1.1Lcm>/Porcn<+>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0004323I129S1Sv129X1SvJC57BL6CBAPorcntm11LcmPorcnTgSox2cre1Amc0Porcntm11LcmPorcnTgSox2cre1Amc
• abnormal mesoderm development_Porcn<tm1.1Lcm>/Y,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0001680I129S1Sv129X1SvJC57BL6CBAPorcntm11LcmYTgSox2cre1Amc0Porcntm11LcmTgSox2cre1Amc
• cleft palate_Porcn<tm1.1Lcm>/Porcn<+>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0000111I129S1Sv129X1SvJC57BL6CBAPorcntm11LcmPorcnTgSox2cre1Amc0Porcntm11LcmPorcnTgSox2cre1Amc
• abnormal tail morphology_Porcn<tm1.1Lcm>/Porcn<+>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0002111I129S1Sv129X1SvJC57BL6CBAPorcntm11LcmPorcnTgSox2cre1Amc0Porcntm11LcmPorcnTgSox2cre1Amc
• absent ulna_Porcn<tm1.1Lcm>/Porcn<+>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0004360I129S1Sv129X1SvJC57BL6CBAPorcntm11LcmPorcnTgSox2cre1Amc0Porcntm11LcmPorcnTgSox2cre1Amc
• thin dermal layer_Porcn<tm1.1Lcm>/Porcn<+>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0001244I129S1Sv129X1SvJC57BL6CBAPorcntm11LcmPorcnTgSox2cre1Amc0Porcntm11LcmPorcnTgSox2cre1Amc
• no abnormal phenotype detected_Porcn<tm1.1Lcm>/Porcn<tm1.1Lcm>
  http://metadb.riken.jp/0002169I129S1Sv129X1SvJC57BL6Porcntm11LcmPorcntm11LcmPorcntm11Lcm
• omphalocele_Porcn<tm1.1Lcm>/Porcn<+>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0003052I129S1Sv129X1SvJC57BL6CBAPorcntm11LcmPorcnTgSox2cre1Amc0Porcntm11LcmPorcnTgSox2cre1Amc
• abnormal autopod morphology_Porcn<tm1.1Lcm>/Y,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0000572I129S1Sv129X1SvJC57BL6Porcntm11LcmYTgMsx2cre5Rem0Porcntm11LcmTgMsx2cre5Rem
• abnormal dermal layer morphology_Porcn<tm1.1Lcm>/Y,Tg(Msx2-cre)5Rem/0
  http://metadb.riken.jp/0001243I129S1Sv129X1SvJC57BL6Porcntm11LcmYTgMsx2cre5Rem0Porcntm11LcmTgMsx2cre5Rem
• no abnormal phenotype detected_Porcn<tm1.1Lcm>/Y
  http://metadb.riken.jp/0002169I129S1Sv129X1SvJC57BL6Porcntm11LcmYPorcntm11Lcm
• short limbs_Porcn<tm1.1Lcm>/Y,Tg(Prrx1-cre)1Cjt/0
  http://metadb.riken.jp/0000547I129S1Sv129X1SvJC57BL6SJLJPorcntm11LcmYTgPrrx1cre1Cjt0Porcntm11LcmTgPrrx1cre1Cjt
• caudal body truncation_Porcn<tm1.1Lcm>/Porcn<+>,Tg(Sox2-cre)1Amc/0
  http://metadb.riken.jp/0004073I129S1Sv129X1SvJC57BL6CBAPorcntm11LcmPorcnTgSox2cre1Amc0Porcntm11LcmPorcnTgSox2cre1Amc