Wanglong. Qiu, et.al., Disruption of p16 and activation of Kras in pancreas increase ductal adenocarcinoma formation and metastasis in vivo., Oncotarget, 2011, 2

http://rdf.ncbi.nlm.nih.gov/pubmed/22113502

Wanglong. Qiu, et.al., Disruption of p16 and activation of Kras in pancreas increase ductal adenocarcinoma formation and metastasis in vivo., Oncotarget, 2011, 2

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cdkn2a<tm1.1Gsu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5502377

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• jaundice_Cdkn2a<tm1.1Gsu>/Cdkn2a<tm1.1Gsu>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0000611I129S4SvJae129S4SvJaeSorC57BL6JFVBNCdkn2atm11GsuCdkn2atm11GsuKrastm4TyjKrasTgPdx1cre6Tuv0KrasKrastm4TyjTgPdx1cre6TuvCdkn2atm11Gsu
• jaundice_Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0000611I129S4SvJae129S6SvEvTacFVBNCdkn2atm21RdpCdkn2atm21RdpKrastm4TyjKrasTgPdx1cre6Tuv0KrasCdkn2atm21RdpTgPdx1cre6TuvKrastm4Tyj
• weight loss_Cdkn2a<tm1.1Gsu>/Cdkn2a<tm1.1Gsu>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0001263I129S4SvJae129S4SvJaeSorC57BL6JFVBNCdkn2atm11GsuCdkn2atm11GsuKrastm4TyjKrasTgPdx1cre6Tuv0KrasKrastm4TyjTgPdx1cre6TuvCdkn2atm11Gsu
• weight loss_Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0001263I129S4SvJae129S6SvEvTacFVBNCdkn2atm21RdpCdkn2atm21RdpKrastm4TyjKrasTgPdx1cre6Tuv0KrasCdkn2atm21RdpTgPdx1cre6TuvKrastm4Tyj
• distended abdomen_Cdkn2a<tm1.1Gsu>/Cdkn2a<tm1.1Gsu>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0001270I129S4SvJae129S4SvJaeSorC57BL6JFVBNCdkn2atm11GsuCdkn2atm11GsuKrastm4TyjKrasTgPdx1cre6Tuv0KrasKrastm4TyjTgPdx1cre6TuvCdkn2atm11Gsu
• distended abdomen_Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0001270I129S4SvJae129S6SvEvTacFVBNCdkn2atm21RdpCdkn2atm21RdpKrastm4TyjKrasTgPdx1cre6Tuv0KrasCdkn2atm21RdpTgPdx1cre6TuvKrastm4Tyj
他12件を見る
• premature death_Cdkn2a<tm1.1Gsu>/Cdkn2a<tm1.1Gsu>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0002083I129S4SvJae129S4SvJaeSorC57BL6JFVBNCdkn2atm11GsuCdkn2atm11GsuKrastm4TyjKrasTgPdx1cre6Tuv0KrasKrastm4TyjTgPdx1cre6TuvCdkn2atm11Gsu
• premature death_Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0002083I129S4SvJae129S6SvEvTacFVBNCdkn2atm21RdpCdkn2atm21RdpKrastm4TyjKrasTgPdx1cre6Tuv0KrasCdkn2atm21RdpTgPdx1cre6TuvKrastm4Tyj
• ascites_Cdkn2a<tm1.1Gsu>/Cdkn2a<tm1.1Gsu>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0005324I129S4SvJae129S4SvJaeSorC57BL6JFVBNCdkn2atm11GsuCdkn2atm11GsuKrastm4TyjKrasTgPdx1cre6Tuv0KrasKrastm4TyjTgPdx1cre6TuvCdkn2atm11Gsu
• ascites_Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0005324I129S4SvJae129S6SvEvTacFVBNCdkn2atm21RdpCdkn2atm21RdpKrastm4TyjKrasTgPdx1cre6Tuv0KrasCdkn2atm21RdpTgPdx1cre6TuvKrastm4Tyj
• increased pancreas adenoma incidence_Cdkn2a<tm1.1Gsu>/Cdkn2a<tm1.1Gsu>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0009043I129S4SvJae129S4SvJaeSorC57BL6JFVBNCdkn2atm11GsuCdkn2atm11GsuKrastm4TyjKrasTgPdx1cre6Tuv0KrasKrastm4TyjTgPdx1cre6TuvCdkn2atm11Gsu
• increased pancreas adenoma incidence_Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0009043I129S4SvJae129S6SvEvTacFVBNCdkn2atm21RdpCdkn2atm21RdpKrastm4TyjKrasTgPdx1cre6Tuv0KrasCdkn2atm21RdpTgPdx1cre6TuvKrastm4Tyj
• increased pancreatic intraepithelial neoplasia incidence_Cdkn2a<tm1.1Gsu>/Cdkn2a<tm1.1Gsu>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0009152I129S4SvJae129S4SvJaeSorC57BL6JFVBNCdkn2atm11GsuCdkn2atm11GsuKrastm4TyjKrasTgPdx1cre6Tuv0KrasKrastm4TyjTgPdx1cre6TuvCdkn2atm11Gsu
• increased pancreatic intraepithelial neoplasia incidence_Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0009152I129S4SvJae129S6SvEvTacFVBNCdkn2atm21RdpCdkn2atm21RdpKrastm4TyjKrasTgPdx1cre6Tuv0KrasCdkn2atm21RdpTgPdx1cre6TuvKrastm4Tyj
• increased pancreas tumor incidence_Cdkn2a<tm1.1Gsu>/Cdkn2a<tm1.1Gsu>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0009153I129S4SvJae129S4SvJaeSorC57BL6JFVBNCdkn2atm11GsuCdkn2atm11GsuKrastm4TyjKrasTgPdx1cre6Tuv0KrasKrastm4TyjTgPdx1cre6TuvCdkn2atm11Gsu
• increased pancreas tumor incidence_Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0009153I129S4SvJae129S6SvEvTacFVBNCdkn2atm21RdpCdkn2atm21RdpKrastm4TyjKrasTgPdx1cre6Tuv0KrasCdkn2atm21RdpTgPdx1cre6TuvKrastm4Tyj
• increased adenocarcinoma incidence_Cdkn2a<tm1.1Gsu>/Cdkn2a<tm1.1Gsu>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0009308I129S4SvJae129S4SvJaeSorC57BL6JFVBNCdkn2atm11GsuCdkn2atm11GsuKrastm4TyjKrasTgPdx1cre6Tuv0KrasKrastm4TyjTgPdx1cre6TuvCdkn2atm11Gsu
• increased adenocarcinoma incidence_Cdkn2a<tm2.1Rdp>/Cdkn2a<tm2.1Rdp>,Kras<tm4Tyj>/Kras<+>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0009308I129S4SvJae129S6SvEvTacFVBNCdkn2atm21RdpCdkn2atm21RdpKrastm4TyjKrasTgPdx1cre6Tuv0KrasCdkn2atm21RdpTgPdx1cre6TuvKrastm4Tyj

class

http://purl.org/net/cito/citesAsAuthority

• Cdkn2a<tm1.1Gsu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5502377