Ichiro. Onoyama, et.al., Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis., The Journal of experimental medicine, 2007, 204

http://rdf.ncbi.nlm.nih.gov/pubmed/17984302

Ichiro. Onoyama, et.al., Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis., The Journal of experimental medicine, 2007, 204

rdfs:label

http://www.w3.org/2000/01/rdf-schema#label

• Ichiro. Onoyama, et.al., Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis., The Journal of experimental medicine, 2007, 204

article

http://www.w3.org/2000/01/rdf-schema#seeAlso

• [Blank]

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• prenatal lethality, complete penetrance_Fbxw7<tm1.1Kei>/Fbxw7<tm1.1Kei>
  http://metadb.riken.jp/0011091IC57BL6Fbxw7tm11KeiFbxw7tm11KeiFbxw7tm11Kei
• increased lymphoma incidence_Fbxw7<tm1Kei>/Fbxw7<tm1Kei>,Tg(Lck-cre)1Cwi/?
  http://metadb.riken.jp/0012431IC57BL6Fbxw7tm1KeiFbxw7tm1KeiTgLckcre1CwiFbxw7tm1KeiTgLckcre1Cwi
• increased T cell apoptosis_Fbxw7<tm1Kei>/Fbxw7<tm1Kei>,Tg(Lck-cre)1Cwi/?
  http://metadb.riken.jp/0006413IC57BL6Fbxw7tm1KeiFbxw7tm1KeiTgLckcre1CwiFbxw7tm1KeiTgLckcre1Cwi
• no abnormal phenotype detected_Fbxw7<tm1Kei>/Fbxw7<tm1Kei>
  http://metadb.riken.jp/0002169IC57BL6Fbxw7tm1KeiFbxw7tm1KeiFbxw7tm1Kei
• abnormal vascular development_Fbxw7<tm1.1Kei>/Fbxw7<tm1.1Kei>
  http://metadb.riken.jp/0000259IC57BL6Fbxw7tm11KeiFbxw7tm11KeiFbxw7tm11Kei
• increased T cell derived lymphoma incidence_Fbxw7<tm1Kei>/Fbxw7<tm1Kei>,Trp53<tm1Tyj>/Trp53<tm1Tyj>,Tg(Lck-cre)1Cwi/?
  http://metadb.riken.jp/0002024I129S2SvPasC57BL6Fbxw7tm1KeiFbxw7tm1KeiTrp53tm1TyjTrp53tm1TyjTgLckcre1CwiFbxw7tm1KeiTrp53tm1TyjTgLckcre1Cwi
• arrested T cell differentiation_Fbxw7<tm1Kei>/Fbxw7<tm1Kei>,Tg(Lck-cre)1Cwi/?
  http://metadb.riken.jp/0001825IC57BL6Fbxw7tm1KeiFbxw7tm1KeiTgLckcre1CwiFbxw7tm1KeiTgLckcre1Cwi
• increased double-positive T cell number_Fbxw7<tm1Kei>/Fbxw7<tm1Kei>,Rbpj<tm1Hon>/Rbpj<tm1Hon>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0005091I129P2OlaHsdC57BL6DBA2Fbxw7tm1KeiFbxw7tm1KeiRbpjtm1HonRbpjtm1HonTgCd4cre1CwiRbpjtm1HonTgCd4cre1CwiFbxw7tm1Kei
• increased double-positive T cell number_Fbxw7<tm1Kei>/Fbxw7<tm1Kei>,Tg(Lck-cre)1Cwi/?
  http://metadb.riken.jp/0005091IC57BL6Fbxw7tm1KeiFbxw7tm1KeiTgLckcre1CwiFbxw7tm1KeiTgLckcre1Cwi
• enlarged thymus_Fbxw7<tm1Kei>/Fbxw7<tm1Kei>,Tg(Lck-cre)1Cwi/?
  http://metadb.riken.jp/0000709IC57BL6Fbxw7tm1KeiFbxw7tm1KeiTgLckcre1CwiFbxw7tm1KeiTgLckcre1Cwi
• increased lymphoma incidence_Fbxw7<tm1Kei>/Fbxw7<tm1Kei>,Trp53<tm1Tyj>/Trp53<tm1Tyj>,Tg(Lck-cre)1Cwi/?
  http://metadb.riken.jp/0012431I129S2SvPasC57BL6Fbxw7tm1KeiFbxw7tm1KeiTrp53tm1TyjTrp53tm1TyjTgLckcre1CwiFbxw7tm1KeiTrp53tm1TyjTgLckcre1Cwi
• decreased single-positive T cell number_Fbxw7<tm1Kei>/Fbxw7<tm1Kei>,Tg(Lck-cre)1Cwi/?
  http://metadb.riken.jp/0008083IC57BL6Fbxw7tm1KeiFbxw7tm1KeiTgLckcre1CwiFbxw7tm1KeiTgLckcre1Cwi
• increased double-positive T cell number_Fbxw7<tm1Kei>/Fbxw7<tm1Kei>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0005091IC57BL6DBA2Fbxw7tm1KeiFbxw7tm1KeiTgCd4cre1CwiFbxw7tm1KeiTgCd4cre1Cwi
• abnormal T cell activation_Fbxw7<tm1Kei>/Fbxw7<tm1Kei>,Tg(Lck-cre)1Cwi/?
  http://metadb.riken.jp/0001828IC57BL6Fbxw7tm1KeiFbxw7tm1KeiTgLckcre1CwiFbxw7tm1KeiTgLckcre1Cwi
• premature death_Fbxw7<tm1Kei>/Fbxw7<tm1Kei>,Tg(Lck-cre)1Cwi/?
  http://metadb.riken.jp/0002083IC57BL6Fbxw7tm1KeiFbxw7tm1KeiTgLckcre1CwiFbxw7tm1KeiTgLckcre1Cwi

class

http://purl.org/net/cito/citesAsAuthority

• Fbxw7<tm1Kei>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3767577
• Fbxw7<tm1.1Kei>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3767578

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• no abnormal phenotype detected in RBRC06393
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1009907

Class

http://purl.org/net/cito/citesAsAuthority

• B6;129P2-Fbxw7<tm1Kei>
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC06393

allele

http://purl.org/net/cito/citesAsAuthority

• Fbxw7<tm1Kei>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3767577
• Fbxw7<tm1.1Kei>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3767578

BRC マウスの系統

http://purl.org/net/cito/citesAsAuthority

• B6;129P2-Fbxw7<tm1Kei>
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC06393