Michela. Di Salvio, et.al., Otx2 controls neuron subtype identity in ventral tegmental area and antagonizes vulnerability to MPTP., Nature neuroscience, 2010, 13

http://rdf.ncbi.nlm.nih.gov/pubmed/21057506

Michela. Di Salvio, et.al., Otx2 controls neuron subtype identity in ventral tegmental area and antagonizes vulnerability to MPTP., Nature neuroscience, 2010, 13

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1.1(Otx2)Daac>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4887449

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased susceptibility to dopaminergic neuron neurotoxicity_Gt(ROSA)26Sor<tm1.1(Otx2)Daac>/Gt(ROSA)26Sor<tm1.1(Otx2)Daac>,Slc6a3<tm1.1(cre)Bkmn>/Slc6a3<+>
  http://metadb.riken.jp/0011452I129P2OlaHsdC57BL6DBA2GtROSA26Sortm11Otx2DaacGtROSA26Sortm11Otx2DaacSlc6a3tm11creBkmnSlc6a3GtROSA26Sortm11Otx2DaacSlc6a3Slc6a3tm11creBkmn
• decreased susceptibility to dopaminergic neuron neurotoxicity_Gt(ROSA)26Sor<tm1.1(Otx2)Daac>/Gt(ROSA)26Sor<tm1.1(Otx2)Daac>,Slc6a3<tm1.1(cre)Bkmn>/Slc6a3<+>,Tg(CAG-Otx2,-GFP)21Asim/0
  http://metadb.riken.jp/0011452I129P2OlaHsdC57BL6DBA2GtROSA26Sortm11Otx2DaacGtROSA26Sortm11Otx2DaacSlc6a3tm11creBkmnSlc6a3TgCAGOtx2GFP21Asim0Slc6a3tm11creBkmnSlc6a3GtROSA26Sortm11Otx2DaacTgCAGOtx2GFP21Asim
• decreased dopaminergic neuron number_Gt(ROSA)26Sor<tm1.1(Otx2)Daac>/Gt(ROSA)26Sor<tm1.1(Otx2)Daac>,Slc6a3<tm1.1(cre)Bkmn>/Slc6a3<+>,Tg(CAG-Otx2,-GFP)21Asim/0
  http://metadb.riken.jp/0011448I129P2OlaHsdC57BL6DBA2GtROSA26Sortm11Otx2DaacGtROSA26Sortm11Otx2DaacSlc6a3tm11creBkmnSlc6a3TgCAGOtx2GFP21Asim0Slc6a3tm11creBkmnSlc6a3GtROSA26Sortm11Otx2DaacTgCAGOtx2GFP21Asim
• abnormal neuron differentiation_Otx2<tm6Asim>/Otx2<tm11Asim>,Slc6a3<tm1.1(cre)Bkmn>/Slc6a3<+>
  http://metadb.riken.jp/0009937I129P2OlaHsd129S1Sv129X1SvJOtx2tm6AsimOtx2tm11AsimSlc6a3tm11creBkmnSlc6a3Slc6a3Otx2tm11AsimSlc6a3tm11creBkmnOtx2tm6Asim
• decreased susceptibility to dopaminergic neuron neurotoxicity_Gt(ROSA)26Sor<tm1.1(Otx2)Daac>/Gt(ROSA)26Sor<+>,Slc6a3<tm1.1(cre)Bkmn>/Slc6a3<+>
  http://metadb.riken.jp/0011452I129P2OlaHsdC57BL6DBA2GtROSA26Sortm11Otx2DaacGtROSA26SorSlc6a3tm11creBkmnSlc6a3GtROSA26Sortm11Otx2DaacSlc6a3GtROSA26SorSlc6a3tm11creBkmn
• decreased dopaminergic neuron number_Gt(ROSA)26Sor<tm1.1(Otx2)Daac>/Gt(ROSA)26Sor<tm1.1(Otx2)Daac>,Slc6a3<tm1.1(cre)Bkmn>/Slc6a3<+>
  http://metadb.riken.jp/0011448I129P2OlaHsdC57BL6DBA2GtROSA26Sortm11Otx2DaacGtROSA26Sortm11Otx2DaacSlc6a3tm11creBkmnSlc6a3GtROSA26Sortm11Otx2DaacSlc6a3Slc6a3tm11creBkmn
• increased susceptibility to dopaminergic neuron neurotoxicity_Otx2<tm6Asim>/Otx2<tm11Asim>,Slc6a3<tm1.1(cre)Bkmn>/Slc6a3<+>
  http://metadb.riken.jp/0011451I129P2OlaHsd129S1Sv129X1SvJOtx2tm6AsimOtx2tm11AsimSlc6a3tm11creBkmnSlc6a3Slc6a3Otx2tm11AsimSlc6a3tm11creBkmnOtx2tm6Asim

class

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1.1(Otx2)Daac>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4887449

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD03264
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03264
• CD03051
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03051
• CD03196
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03196
• CD03178
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD03178
• CD40247
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD40247
• CD11691
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD11691