Jun Won. Park, et.al., Cooperativity of E-cadherin and Smad4 loss to promote diffuse-type gastric adenocarcinoma and metastasis., Molecular cancer research : MCR, 2014, 12

http://rdf.ncbi.nlm.nih.gov/pubmed/24784840

Jun Won. Park, et.al., Cooperativity of E-cadherin and Smad4 loss to promote diffuse-type gastric adenocarcinoma and metastasis., Molecular cancer research : MCR, 2014, 12

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased mammary adenocarcinoma incidence_Smad4<tm2.1Cxd>/Smad4<tm2.1Cxd>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(MMTV-cre)7Mul/0
  http://metadb.riken.jp/0001883I129P2OlaHsd129S6SvEvTacFVBNSmad4tm21CxdSmad4tm21CxdTrp53tm1BrnTrp53tm1BrnTgMMTVcre7Mul0TgMMTVcre7MulTrp53tm1BrnSmad4tm21Cxd
• increased intestinal adenocarcinoma incidence_Cdh1<tm2Kem>/Cdh1<+>,Smad4<tm2.1Cxd>/Smad4<tm2.1Cxd>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Vil-cre)20Syr/0
  http://metadb.riken.jp/0002957I129C57BL6DBA2Cdh1tm2KemCdh1Smad4tm21CxdSmad4tm21CxdTrp53tm1BrnTrp53tm1BrnTgVilcre20Syr0Smad4tm21CxdTrp53tm1BrnTgVilcre20SyrCdh1tm2KemCdh1
• increased metastatic potential_Smad4<tm2.1Cxd>/Smad4<tm2.1Cxd>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(MMTV-cre)7Mul/0
  http://metadb.riken.jp/0001272I129P2OlaHsd129S6SvEvTacFVBNSmad4tm21CxdSmad4tm21CxdTrp53tm1BrnTrp53tm1BrnTgMMTVcre7Mul0TgMMTVcre7MulTrp53tm1BrnSmad4tm21Cxd
• premature death_Cdh1<tm2Kem>/Cdh1<+>,Smad4<tm2.1Cxd>/Smad4<tm2.1Cxd>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0002083I129C57BL6FVBNCdh1tm2KemCdh1Smad4tm21CxdSmad4tm21CxdTrp53tm1BrnTrp53tm1BrnTgPdx1cre6Tuv0Smad4tm21CxdTgPdx1cre6TuvCdh1tm2KemCdh1Trp53tm1Brn
• increased metastatic potential_Cdh1<tm2Kem>/Cdh1<+>,Smad4<tm2.1Cxd>/Smad4<tm2.1Cxd>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0001272I129C57BL6FVBNCdh1tm2KemCdh1Smad4tm21CxdSmad4tm21CxdTrp53tm1BrnTrp53tm1BrnTgPdx1cre6Tuv0Smad4tm21CxdTgPdx1cre6TuvCdh1tm2KemCdh1Trp53tm1Brn
• increased duodenum adenocarcinoma incidence_Cdh1<tm2Kem>/Cdh1<+>,Smad4<tm2.1Cxd>/Smad4<tm2.1Cxd>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0009311I129C57BL6FVBNCdh1tm2KemCdh1Smad4tm21CxdSmad4tm21CxdTrp53tm1BrnTrp53tm1BrnTgPdx1cre6Tuv0Smad4tm21CxdTgPdx1cre6TuvCdh1tm2KemCdh1Trp53tm1Brn
• increased metastatic potential_Cdh1<tm2Kem>/Cdh1<+>,Smad4<tm2.1Cxd>/Smad4<tm2.1Cxd>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(MMTV-cre)7Mul/0
  http://metadb.riken.jp/0001272I129C57BL6FVBNCdh1tm2KemCdh1Smad4tm21CxdSmad4tm21CxdTrp53tm1BrnTrp53tm1BrnTgMMTVcre7Mul0Trp53tm1BrnTgMMTVcre7MulCdh1tm2KemCdh1Smad4tm21Cxd
• increased gastric adenocarcinoma incidence_Cdh1<tm2Kem>/Cdh1<+>,Smad4<tm2.1Cxd>/Smad4<tm2.1Cxd>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0008010I129C57BL6FVBNCdh1tm2KemCdh1Smad4tm21CxdSmad4tm21CxdTrp53tm1BrnTrp53tm1BrnTgPdx1cre6Tuv0Smad4tm21CxdTgPdx1cre6TuvCdh1tm2KemCdh1Trp53tm1Brn
• increased squamous cell carcinoma incidence_Cdh1<tm2Kem>/Cdh1<+>,Smad4<tm2.1Cxd>/Smad4<tm2.1Cxd>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0004207I129C57BL6FVBNCdh1tm2KemCdh1Smad4tm21CxdSmad4tm21CxdTrp53tm1BrnTrp53tm1BrnTgPdx1cre6Tuv0Smad4tm21CxdTgPdx1cre6TuvCdh1tm2KemCdh1Trp53tm1Brn
• increased intestinal adenocarcinoma incidence_Smad4<tm2.1Cxd>/Smad4<tm2.1Cxd>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Vil-cre)20Syr/0
  http://metadb.riken.jp/0002957I129P2OlaHsd129S6SvEvTacC57BL6DBA2Smad4tm21CxdSmad4tm21CxdTrp53tm1BrnTrp53tm1BrnTgVilcre20Syr0TgVilcre20SyrTrp53tm1BrnSmad4tm21Cxd
• increased mammary adenocarcinoma incidence_Cdh1<tm2Kem>/Cdh1<+>,Smad4<tm2.1Cxd>/Smad4<tm2.1Cxd>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(MMTV-cre)7Mul/0
  http://metadb.riken.jp/0001883I129C57BL6FVBNCdh1tm2KemCdh1Smad4tm21CxdSmad4tm21CxdTrp53tm1BrnTrp53tm1BrnTgMMTVcre7Mul0Trp53tm1BrnTgMMTVcre7MulCdh1tm2KemCdh1Smad4tm21Cxd
• increased gastric adenocarcinoma incidence_Cdh1<tm2Kem>/Cdh1<tm2Kem>,Smad4<tm2.1Cxd>/Smad4<tm2.1Cxd>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Pdx1-cre)6Tuv/0
  http://metadb.riken.jp/0008010I129C57BL6FVBNCdh1tm2KemCdh1tm2KemSmad4tm21CxdSmad4tm21CxdTrp53tm1BrnTrp53tm1BrnTgPdx1cre6Tuv0Trp53tm1BrnCdh1tm2KemTgPdx1cre6TuvSmad4tm21Cxd