Seiichi. Nagano, et.al., A cysteine residue affects the conformational state and neuronal toxicity of mutant SOD1 in mice: relevance to the pathogenesis of ALS., Human molecular genetics, 2015, 24

http://rdf.ncbi.nlm.nih.gov/pubmed/25762155

Seiichi. Nagano, et.al., A cysteine residue affects the conformational state and neuronal toxicity of mutant SOD1 in mice: relevance to the pathogenesis of ALS., Human molecular genetics, 2015, 24

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(SOD1*H46R)IAra
  http://metadb.riken.jp/db/mgi_rdf/MGI:5699320
• Tg(SOD1*H46R)LAra
  http://metadb.riken.jp/db/mgi_rdf/MGI:5699326
• Tg(SOD1*H46R*C111S)QAra
  http://metadb.riken.jp/db/mgi_rdf/MGI:5699327
• Tg(SOD1*H46R*C111S)PAra
  http://metadb.riken.jp/db/mgi_rdf/MGI:5699338

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• paralysis_Tg(SOD1*H46R*C111S)PAra/0
  http://metadb.riken.jp/0000753IC57BL6DBA2TgSOD1H46RC111SPAra0TgSOD1H46RC111SPAra
• paralysis_Tg(SOD1*H46R*C111S)PAra/Tg(SOD1*H46R*C111S)PAra
  http://metadb.riken.jp/0000753IC57BL6DBA2TgSOD1H46RC111SPAraTgSOD1H46RC111SPAraTgSOD1H46RC111SPAra
• paralysis_Tg(SOD1*H46R*C111S)QAra/0
  http://metadb.riken.jp/0000753IC57BL6DBA2TgSOD1H46RC111SQAra0TgSOD1H46RC111SQAra
• paralysis_Tg(SOD1*H46R)IAra/0
  http://metadb.riken.jp/0000753IC57BL6DBA2TgSOD1H46RIAra0TgSOD1H46RIAra
• paralysis_Tg(SOD1*H46R)LAra/0
  http://metadb.riken.jp/0000753IC57BL6DBA2TgSOD1H46RLAra0TgSOD1H46RLAra
• motor neuron degeneration_Tg(SOD1*H46R*C111S)PAra/Tg(SOD1*H46R*C111S)PAra
  http://metadb.riken.jp/0000938IC57BL6DBA2TgSOD1H46RC111SPAraTgSOD1H46RC111SPAraTgSOD1H46RC111SPAra
他22件を見る
• motor neuron degeneration_Tg(SOD1*H46R)LAra/0
  http://metadb.riken.jp/0000938IC57BL6DBA2TgSOD1H46RLAra0TgSOD1H46RLAra
• decreased motor neuron number_Tg(SOD1*H46R)LAra/0
  http://metadb.riken.jp/0000939IC57BL6DBA2TgSOD1H46RLAra0TgSOD1H46RLAra
• abnormal spinal cord morphology_Tg(SOD1*H46R)LAra/0
  http://metadb.riken.jp/0000955IC57BL6DBA2TgSOD1H46RLAra0TgSOD1H46RLAra
• weight loss_Tg(SOD1*H46R)IAra/0
  http://metadb.riken.jp/0001263IC57BL6DBA2TgSOD1H46RIAra0TgSOD1H46RIAra
• weight loss_Tg(SOD1*H46R)LAra/0
  http://metadb.riken.jp/0001263IC57BL6DBA2TgSOD1H46RLAra0TgSOD1H46RLAra
• impaired coordination_Tg(SOD1*H46R)IAra/0
  http://metadb.riken.jp/0001405IC57BL6DBA2TgSOD1H46RIAra0TgSOD1H46RIAra
• impaired coordination_Tg(SOD1*H46R)LAra/0
  http://metadb.riken.jp/0001405IC57BL6DBA2TgSOD1H46RLAra0TgSOD1H46RLAra
• premature death_Tg(SOD1*H46R*C111S)PAra/Tg(SOD1*H46R*C111S)PAra
  http://metadb.riken.jp/0002083IC57BL6DBA2TgSOD1H46RC111SPAraTgSOD1H46RC111SPAraTgSOD1H46RC111SPAra
• premature death_Tg(SOD1*H46R*C111S)QAra/0
  http://metadb.riken.jp/0002083IC57BL6DBA2TgSOD1H46RC111SQAra0TgSOD1H46RC111SQAra
• premature death_Tg(SOD1*H46R)IAra/0
  http://metadb.riken.jp/0002083IC57BL6DBA2TgSOD1H46RIAra0TgSOD1H46RIAra
• premature death_Tg(SOD1*H46R)LAra/0
  http://metadb.riken.jp/0002083IC57BL6DBA2TgSOD1H46RLAra0TgSOD1H46RLAra
• muscular atrophy_Tg(SOD1*H46R)LAra/0
  http://metadb.riken.jp/0002269IC57BL6DBA2TgSOD1H46RLAra0TgSOD1H46RLAra
• abnormal tibialis anterior morphology_Tg(SOD1*H46R)LAra/0
  http://metadb.riken.jp/0003083IC57BL6DBA2TgSOD1H46RLAra0TgSOD1H46RLAra
• astrocytosis_Tg(SOD1*H46R*C111S)PAra/0
  http://metadb.riken.jp/0003354IC57BL6DBA2TgSOD1H46RC111SPAra0TgSOD1H46RC111SPAra
• astrocytosis_Tg(SOD1*H46R*C111S)PAra/Tg(SOD1*H46R*C111S)PAra
  http://metadb.riken.jp/0003354IC57BL6DBA2TgSOD1H46RC111SPAraTgSOD1H46RC111SPAraTgSOD1H46RC111SPAra
• astrocytosis_Tg(SOD1*H46R*C111S)QAra/0
  http://metadb.riken.jp/0003354IC57BL6DBA2TgSOD1H46RC111SQAra0TgSOD1H46RC111SQAra
• astrocytosis_Tg(SOD1*H46R)LAra/0
  http://metadb.riken.jp/0003354IC57BL6DBA2TgSOD1H46RLAra0TgSOD1H46RLAra
• microgliosis_Tg(SOD1*H46R*C111S)PAra/0
  http://metadb.riken.jp/0008918IC57BL6DBA2TgSOD1H46RC111SPAra0TgSOD1H46RC111SPAra
• microgliosis_Tg(SOD1*H46R*C111S)PAra/Tg(SOD1*H46R*C111S)PAra
  http://metadb.riken.jp/0008918IC57BL6DBA2TgSOD1H46RC111SPAraTgSOD1H46RC111SPAraTgSOD1H46RC111SPAra
• microgliosis_Tg(SOD1*H46R*C111S)QAra/0
  http://metadb.riken.jp/0008918IC57BL6DBA2TgSOD1H46RC111SQAra0TgSOD1H46RC111SQAra
• microgliosis_Tg(SOD1*H46R)LAra/0
  http://metadb.riken.jp/0008918IC57BL6DBA2TgSOD1H46RLAra0TgSOD1H46RLAra
• decreased tibialis anterior weight_Tg(SOD1*H46R)LAra/0
  http://metadb.riken.jp/0009428IC57BL6DBA2TgSOD1H46RLAra0TgSOD1H46RLAra

class

http://purl.org/net/cito/citesAsAuthority

• Tg(SOD1*H46R)IAra
  http://metadb.riken.jp/db/mgi_rdf/MGI:5699320
• Tg(SOD1*H46R)LAra
  http://metadb.riken.jp/db/mgi_rdf/MGI:5699326
• Tg(SOD1*H46R*C111S)QAra
  http://metadb.riken.jp/db/mgi_rdf/MGI:5699327
• Tg(SOD1*H46R*C111S)PAra
  http://metadb.riken.jp/db/mgi_rdf/MGI:5699338

article

http://www.w3.org/2000/01/rdf-schema#seeAlso

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BRC マウスの系統

http://purl.org/net/cito/citesAsAuthority

• Tg(SOD1*H46R)IAra
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC09642
• Tg(SOD1*H46R)LAra
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC09643
• Tg(SOD1*H46R*C111S)QAra
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC09644

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• impaired coordination in RBRC09642
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020334
• paralysis in RBRC09642
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020335
• weight loss in RBRC09642
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020336
• premature death in RBRC09642
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020337
• impaired coordination in RBRC09643
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020338
• paralysis in RBRC09643
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020339
他16件を見る
• weight loss in RBRC09643
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020340
• microgliosis in RBRC09643
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020341
• premature death in RBRC09643
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020342
• abnormal tibialis anterior morphology in RBRC09643
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020343
• decreased tibialis anterior weight in RBRC09643
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020344
• muscular atrophy in RBRC09643
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020345
• astrocytosis in RBRC09643
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020346
• abnormal spinal cord morphology in RBRC09643
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020347
• decreased motor neuron number in RBRC09643
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020348
• motor neuron degeneration in RBRC09643
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020349
• paralysis in RBRC09644
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020350
• growth/size/body region phenotype in RBRC09644
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020351
• microgliosis in RBRC09644
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020352
• premature death in RBRC09644
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020353
• nervous system phenotype in RBRC09644
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020354
• astrocytosis in RBRC09644
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020355

article

http://www.w3.org/2000/01/rdf-schema#seeAlso

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