Seiichi. Nagano, et.al., A cysteine residue affects the conformational state and neuronal toxicity of mutant SOD1 in mice: relevance to the pathogenesis of ALS., Human molecular genetics, 2015, 24

http://rdf.ncbi.nlm.nih.gov/pubmed/25762155

Seiichi. Nagano, et.al., A cysteine residue affects the conformational state and neuronal toxicity of mutant SOD1 in mice: relevance to the pathogenesis of ALS., Human molecular genetics, 2015, 24

rdfs:label

http://www.w3.org/2000/01/rdf-schema#label

• Seiichi. Nagano, et.al., A cysteine residue affects the conformational state and neuronal toxicity of mutant SOD1 in mice: relevance to the pathogenesis of ALS., Human molecular genetics, 2015, 24

article

http://www.w3.org/2000/01/rdf-schema#seeAlso

• [Blank]
• [Blank]
• [Blank]

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• microgliosis_Tg(SOD1*H46R*C111S)PAra/Tg(SOD1*H46R*C111S)PAra
  http://metadb.riken.jp/0008918IC57BL6DBA2TgSOD1H46RC111SPAraTgSOD1H46RC111SPAraTgSOD1H46RC111SPAra
• paralysis_Tg(SOD1*H46R)LAra/0
  http://metadb.riken.jp/0000753IC57BL6DBA2TgSOD1H46RLAra0TgSOD1H46RLAra
• premature death_Tg(SOD1*H46R*C111S)PAra/Tg(SOD1*H46R*C111S)PAra
  http://metadb.riken.jp/0002083IC57BL6DBA2TgSOD1H46RC111SPAraTgSOD1H46RC111SPAraTgSOD1H46RC111SPAra
• astrocytosis_Tg(SOD1*H46R*C111S)PAra/Tg(SOD1*H46R*C111S)PAra
  http://metadb.riken.jp/0003354IC57BL6DBA2TgSOD1H46RC111SPAraTgSOD1H46RC111SPAraTgSOD1H46RC111SPAra
• muscular atrophy_Tg(SOD1*H46R)LAra/0
  http://metadb.riken.jp/0002269IC57BL6DBA2TgSOD1H46RLAra0TgSOD1H46RLAra
• astrocytosis_Tg(SOD1*H46R*C111S)QAra/0
  http://metadb.riken.jp/0003354IC57BL6DBA2TgSOD1H46RC111SQAra0TgSOD1H46RC111SQAra
• microgliosis_Tg(SOD1*H46R*C111S)QAra/0
  http://metadb.riken.jp/0008918IC57BL6DBA2TgSOD1H46RC111SQAra0TgSOD1H46RC111SQAra
• paralysis_Tg(SOD1*H46R)IAra/0
  http://metadb.riken.jp/0000753IC57BL6DBA2TgSOD1H46RIAra0TgSOD1H46RIAra
• paralysis_Tg(SOD1*H46R*C111S)PAra/0
  http://metadb.riken.jp/0000753IC57BL6DBA2TgSOD1H46RC111SPAra0TgSOD1H46RC111SPAra
• decreased tibialis anterior weight_Tg(SOD1*H46R)LAra/0
  http://metadb.riken.jp/0009428IC57BL6DBA2TgSOD1H46RLAra0TgSOD1H46RLAra
• premature death_Tg(SOD1*H46R*C111S)QAra/0
  http://metadb.riken.jp/0002083IC57BL6DBA2TgSOD1H46RC111SQAra0TgSOD1H46RC111SQAra
• decreased motor neuron number_Tg(SOD1*H46R)LAra/0
  http://metadb.riken.jp/0000939IC57BL6DBA2TgSOD1H46RLAra0TgSOD1H46RLAra
• premature death_Tg(SOD1*H46R)LAra/0
  http://metadb.riken.jp/0002083IC57BL6DBA2TgSOD1H46RLAra0TgSOD1H46RLAra
• paralysis_Tg(SOD1*H46R*C111S)PAra/Tg(SOD1*H46R*C111S)PAra
  http://metadb.riken.jp/0000753IC57BL6DBA2TgSOD1H46RC111SPAraTgSOD1H46RC111SPAraTgSOD1H46RC111SPAra
• impaired coordination_Tg(SOD1*H46R)IAra/0
  http://metadb.riken.jp/0001405IC57BL6DBA2TgSOD1H46RIAra0TgSOD1H46RIAra
• motor neuron degeneration_Tg(SOD1*H46R*C111S)PAra/Tg(SOD1*H46R*C111S)PAra
  http://metadb.riken.jp/0000938IC57BL6DBA2TgSOD1H46RC111SPAraTgSOD1H46RC111SPAraTgSOD1H46RC111SPAra
• abnormal tibialis anterior morphology_Tg(SOD1*H46R)LAra/0
  http://metadb.riken.jp/0003083IC57BL6DBA2TgSOD1H46RLAra0TgSOD1H46RLAra
• impaired coordination_Tg(SOD1*H46R)LAra/0
  http://metadb.riken.jp/0001405IC57BL6DBA2TgSOD1H46RLAra0TgSOD1H46RLAra
• microgliosis_Tg(SOD1*H46R*C111S)PAra/0
  http://metadb.riken.jp/0008918IC57BL6DBA2TgSOD1H46RC111SPAra0TgSOD1H46RC111SPAra
• microgliosis_Tg(SOD1*H46R)LAra/0
  http://metadb.riken.jp/0008918IC57BL6DBA2TgSOD1H46RLAra0TgSOD1H46RLAra
• astrocytosis_Tg(SOD1*H46R)LAra/0
  http://metadb.riken.jp/0003354IC57BL6DBA2TgSOD1H46RLAra0TgSOD1H46RLAra
• premature death_Tg(SOD1*H46R)IAra/0
  http://metadb.riken.jp/0002083IC57BL6DBA2TgSOD1H46RIAra0TgSOD1H46RIAra
• motor neuron degeneration_Tg(SOD1*H46R)LAra/0
  http://metadb.riken.jp/0000938IC57BL6DBA2TgSOD1H46RLAra0TgSOD1H46RLAra
• abnormal spinal cord morphology_Tg(SOD1*H46R)LAra/0
  http://metadb.riken.jp/0000955IC57BL6DBA2TgSOD1H46RLAra0TgSOD1H46RLAra
• weight loss_Tg(SOD1*H46R)LAra/0
  http://metadb.riken.jp/0001263IC57BL6DBA2TgSOD1H46RLAra0TgSOD1H46RLAra
• paralysis_Tg(SOD1*H46R*C111S)QAra/0
  http://metadb.riken.jp/0000753IC57BL6DBA2TgSOD1H46RC111SQAra0TgSOD1H46RC111SQAra
• weight loss_Tg(SOD1*H46R)IAra/0
  http://metadb.riken.jp/0001263IC57BL6DBA2TgSOD1H46RIAra0TgSOD1H46RIAra
• astrocytosis_Tg(SOD1*H46R*C111S)PAra/0
  http://metadb.riken.jp/0003354IC57BL6DBA2TgSOD1H46RC111SPAra0TgSOD1H46RC111SPAra

class

http://purl.org/net/cito/citesAsAuthority

• Tg(SOD1*H46R)LAra
  http://metadb.riken.jp/db/mgi_rdf/MGI:5699326
• Tg(SOD1*H46R*C111S)QAra
  http://metadb.riken.jp/db/mgi_rdf/MGI:5699327
• Tg(SOD1*H46R)IAra
  http://metadb.riken.jp/db/mgi_rdf/MGI:5699320
• Tg(SOD1*H46R*C111S)PAra
  http://metadb.riken.jp/db/mgi_rdf/MGI:5699338

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• motor neuron degeneration in RBRC09643
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020349
• impaired coordination in RBRC09642
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020334
• paralysis in RBRC09644
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020350
• premature death in RBRC09644
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020353
• paralysis in RBRC09643
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020339
• weight loss in RBRC09643
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020340
• impaired coordination in RBRC09643
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020338
• muscular atrophy in RBRC09643
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020345
• astrocytosis in RBRC09643
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020346
• abnormal spinal cord morphology in RBRC09643
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020347
• premature death in RBRC09642
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020337
• nervous system phenotype in RBRC09644
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020354
• paralysis in RBRC09642
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020335
• growth/size/body region phenotype in RBRC09644
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020351
• decreased tibialis anterior weight in RBRC09643
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020344
• weight loss in RBRC09642
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020336
• abnormal tibialis anterior morphology in RBRC09643
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020343
• microgliosis in RBRC09644
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020352
• decreased motor neuron number in RBRC09643
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020348
• astrocytosis in RBRC09644
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020355
• premature death in RBRC09643
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020342
• microgliosis in RBRC09643
  http://metadb.riken.jp/db/rikenbrc_mouse/Phenotype_1020341

Class

http://purl.org/net/cito/citesAsAuthority

• Tg(SOD1*H46R*C111S)QAra
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC09644
• Tg(SOD1*H46R)IAra
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC09642
• Tg(SOD1*H46R)LAra
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC09643

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(SOD1*H46R)LAra
  http://metadb.riken.jp/db/mgi_rdf/MGI:5699326
• Tg(SOD1*H46R*C111S)QAra
  http://metadb.riken.jp/db/mgi_rdf/MGI:5699327
• Tg(SOD1*H46R)IAra
  http://metadb.riken.jp/db/mgi_rdf/MGI:5699320
• Tg(SOD1*H46R*C111S)PAra
  http://metadb.riken.jp/db/mgi_rdf/MGI:5699338

BRC マウスの系統

http://purl.org/net/cito/citesAsAuthority

• Tg(SOD1*H46R*C111S)QAra
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC09644
• Tg(SOD1*H46R)IAra
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC09642
• Tg(SOD1*H46R)LAra
  http://metadb.riken.jp/db/rikenbrc_mouse/RBRC09643